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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T72678 P-gp inhibitor 4

P-gp inhibitor 4 是一种选择性的 P-glycoprotein 调节剂,EC50值为 94 nM。P-gp inhibitor 4 增加药物通过胃肠道屏障的能力,恢复 doxorubicin 在耐药癌细胞中的毒性。
T19649 PF-06273340

PF 6273340,PF 06273340,PF6273340,PF-6273340

Trk receptor Tyrosine Kinase/Adaptors
PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。
TMIH-0399 Norverapamil-d7 HCl

Norverapamil-d7 HCl 是 Norverapamil HCl 的氘代化合物。Norverapamil HCl 的 CAS 号为 67812-42-4。Norverapamil hydrochloride是 Verapamil 的 N-去甲基代谢物,是L型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T35568 BODIPY-aminoacetaldehyde diethyl acetal

BODIPY-aminoacetaldehyde diethyl acetal (BAAA-DA) is a stable precursor to BODIPY-aminoacetaldehyde, a cell-permeable fluorescent substrate for aldehyde dehydrogenase (ALDH).1,2BODIPY-aminoacetaldehyde diethyl acetal is converted under acidic conditions to BODIPY-aminoacetaldehyde (BAAA).2BAAA is cell-permeant and is converted intracellularly by ALDH to BODIPY aminoacetate (BAA), which is retained by cells and can be used to identify cells with high ALDH activity.1BAA is a substrate for the effl...

化合物

P-gp inhibitor 4
Cat.No: T72678
Synonym:
Target:
PF-06273340
Cat.No: T19649
Synonym: PF 6273340,PF 06273340,PF6273340,PF-6273340
Target: Trk receptor
Norverapamil-d7 HCl
Cat.No: TMIH-0399
Synonym:
Target:
BODIPY-aminoacetaldehyde diethyl acetal
Cat.No: T35568
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1757 Hypophyllanthin

叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂

Potassium Channel; Calcium Channel; P-gp Membrane transporter/Ion channel; Metabolism; Neuroscience
Hypophyllanthin 是珠子草中的一种木脂素,能直接抑制 P-gp 的活性,具有很强的抗炎活性。

天然产物

Hypophyllanthin
Cat.No: TN1757
Synonym: 叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂
Target: Potassium Channel, Calcium Channel, P-gp
TargetMol Loading
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