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Search Results for " p-19 "

Targets Recommended: Neurotensin Receptor

11

抑制剂 & 化合物

3

天然产物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1819L	Substance P 1-9 aceate	Neurotensin Receptor	GPCR/G Protein
	Substance P 1-9 aceate 是九肽，可减少豚鼠回肠和膀胱对 P 物质的失活。
TP1819	Substance P (1-9)
	Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
T8533	ML318	Others; Antibiotic	Microbiology/Virology; Others
	ML318 是 PvdQ 酰基转移酶的联芳基腈抑制剂，可以结合在酰基结合位点上，IC50为 20 nM。它抑制铜绿假单胞菌的 IC50为 19 μM。它可防止嘧啶的产生并限制了铜绿假单胞菌在铁限制条件下的生长。
T80285	KAMP-19
	KAMP-19，一款角蛋白衍生的抗菌肽，展示出对铜绿假单胞菌 (P. aeruginosa) 的有效抗菌作用。
T63267	P-gp/BCRP-IN-1
	P-gp/BCRP-IN-1 (compound 19) 是一种潜在的、相对安全的、口服有效的外排转运蛋白(P-gp 和 BCRP) 抑制剂。P-gp/BCRP-IN-1 通过抑制 P-gp 和BCRP 的外排功能产生耐药性逆转，P-gp/BCRP-IN-1可克服紫杉醇的耐药性，提高紫杉醇的口服生物利用度。
T75067	Antimalarial agent 19	Parasite	Microbiology/Virology
	Antimalarial agent 19（compound 6e）是一种活性抗疟疾化合物，对K1型恶性疟原虫和伯氏疟原虫展现出较强的抑制效果，其EC50值分别为0.3 µM和15.3 µM。相较于γ-肝硫平，该化合物具有更好的水溶性、肠道渗透性以及微粒体稳定性。
T62737	KRAS inhibitor-15
	KRAS inhibitor-15 (compound 3-19) 是一种 KRAS G12C 的有效抑制剂 (IC50: 0.954 μM)。KRAS inhibitor-15 在 MIA PaCA-2，A549 细胞中表现出 p-ERK 抑制作用，IC50s 分别为 2.03，>33.3 μM。KRAS inhibitor-15 具有潜力进行胰腺癌、结直肠癌和肺癌的研究。
T38276	Benzomalvin C
	Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/ml in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It was isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E.
T61643	Vonoprazan hydrochloride
	Vonoprazan hydrochloride 是一种高效且具口服活性的质子泵抑制剂 (PPI) 和钾竞争性酸阻断剂 (potassium-competitive acid blocker, P-CAB)，展示出优秀的抗分泌活性。在 pH 为 6.5 的条件下，该化合物可抑制猪胃微粒体内 H+,K+-ATPase 的酶活性，呈现出 19 nM 的 IC50 值。Vonoprazan hydrochloride 主要应用于胃酸相关疾病的研究，包括胃食管反流病和消化性溃疡，并可用于根除幽门螺杆菌。
TP1052	Protein Kinase C (19-31) (TFA)(121545-65-1,free) PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)
	Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate p
T36666	Dehydro Warfarin
	Dehydro warfarin is a metabolite of (±)-warfarin .1It is formed from (±)-warfarin by rat liver microsomes. 1.Kaminsky, L.S., Fasco, M.J., and Guengerich, F.P.Comparison of different forms of liver, kidney, and lung microsomal cytochrome P-450 by immunological inhibition of regio- and stereoselective metabolism of warfarinJ. Biol. Chem.254(19)9657-9662(1979)

化合物

Substance P 1-9 aceate

Cat.No: TP1819L

Target: Neurotensin Receptor

Substance P (1-9)

Cat.No: TP1819

Cat.No: T8533

Target: Others, Antibiotic

Cat.No: T80285

Cat.No: T63267

Antimalarial agent 19

Cat.No: T75067

Target: Parasite

KRAS inhibitor-15

Cat.No: T62737

Cat.No: T38276

Vonoprazan hydrochloride

Cat.No: T61643

Protein Kinase C (19-31) (TFA)(121545-65-1,free)

Cat.No: TP1052

Synonym: PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)

Dehydro Warfarin

Cat.No: T36666

Cat. No.	Product Name	Target	Signaling Pathways
TN3283	8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate	Others	Others
	8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3283，CAS号为 117254-98-5。
TN6287	Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside Anisofolin B
	Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6287，CAS号为 1448779-19-8。
T38262	Sphingosine (d14:1)
	Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).

天然产物

8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate

Cat.No: TN3283

Target: Others

Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside

Cat.No: TN6287

Synonym: Anisofolin B

Sphingosine (d14:1)

Cat.No: T38262

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00406	IL-23 Protein, Human, Recombinant (His) IL23P19,P19,SGRF,IL-23,I...	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-05247	IL-23 Protein, Human, Recombinant (His), Biotinylated IL23P19,IL23,P19,IL-23A,...	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-05648	IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated IL23,IL-23,白细胞介素,白介素,P19,IL23P	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.6 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-02215	Coagulation factor IX/F9 Protein, Human, Recombinant (His) FIX,PTC,Coagulation factor 9,coagulation factor IX,...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is AAB59620.1.
TMPY-04874	IL-23 P19/IL23A Protein, Human, Recombinant (hFc) IL-23A,IL-23,interleukin 23, alpha subunit p	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7.
TMPY-05355	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) P19,Coagulation factor 9,HEMB,FIX,THP<...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.5 kDa and the accession number is P00740-1.
TMPY-04987	IL-23 P19/IL23A Protein, Human, Recombinant (mFc) IL-23,interleukin 23, alpha subunit p1...	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9NPF7.
TMPJ-01100	UBE2V1 Protein, Human, Recombinant (His) TRAF6-Regulated IKK Activator 1 Beta Uev1A,P/OKcl.<...	Human	E. coli
	Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Ly...
TMPY-01335	REG1A Protein, Human, Recombinant (His) regenerating family member 1 alpha,P19...	Human	HEK293 Cells
	REG1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451.
TMPY-05474	REG1A Protein, Human, Recombinant (His), Biotinylated PSPS,R EG,PSPS1,MGC12447...	Human	HEK293 Cells
	REG1A Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P05451.
TMPK-01169	IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated Interleukin-23 subunit α,Interleukin-23 subunit alp...	Mouse	HEK293 Cells
	The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma.
TMPJ-01277	CRT2 Protein, Human, Recombinant CALR3,Calreticulin-3,calreticulin-2,calsperin,CRT2	Human	E. coli
	Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. During spermatogenesis process, Calreticulin-3 may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Defects in CALR3 are the cause of familial hypertrophic cardiomyopathy t...

重组蛋白

IL-23 Protein, Human, Recombinant (His)

Cat.No: TMPY-00406

Species: Human

Expression System: HEK293 Cells

IL-23 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05247

Species: Human

Expression System: HEK293 Cells

IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05648

Species: Human

Expression System: HEK293 Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (His)

Cat.No: TMPY-02215

Species: Human

Expression System: HEK293 Cells

IL-23 P19/IL23A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04874

Species: Human

Expression System: HEK293 Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05355

Species: Human

Expression System: HEK293 Cells

IL-23 P19/IL23A Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04987

Species: Human

Expression System: HEK293 Cells

UBE2V1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01100

Species: Human

Expression System: E. coli

REG1A Protein, Human, Recombinant (His)

Cat.No: TMPY-01335

Species: Human

Expression System: HEK293 Cells

REG1A Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05474

Species: Human

Expression System: HEK293 Cells

IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01169

Species: Mouse

Expression System: HEK293 Cells

CRT2 Protein, Human, Recombinant

Cat.No: TMPJ-01277

Species: Human

Expression System: E. coli

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