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Search Results for " ostenol "

15

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21224	(+)-Fluprostenol Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	(+)-Fluprostenol (AL-5848) 是前列腺素 F2 α 的类似物，是一种前列腺素 F2α 受体 PTGFR 激动剂，可降低输卵管糖蛋白 1 (OVGP1) 的表达。
T5847	Cloprostenol sodium salt ICI 80996 sodium salt,DL-Cloprostenol sodium,氯前列烯醇钠,氯前列烯醇纳,Cloprostenol sodium	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Cloprostenol sodium salt (ICI 80996 sodium salt) 是一种合成的前列腺素类似物，是 PGF2α受体的激动剂，具有黄体溶解性。
T37231	(+)-Cloprostenol methyl ester
	(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprosteno...
T29246	Cloprostenol isopropyl ester (+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester,(+)-Cloprostenol isopropyl ester
	Cloprostenol isopropyl ester is a PGF2α agonist and a similar synthetic prostaglandin F2α (PGF2α), which can induce luteal dissolution in mares during the luteal phase without causing clinical side effects or stress responses.
T32977	Luprostenol
	Luprostenol is a bioactive chemical.
T35321	Zymostenol delta(8)-Cholestenol,5a-Cholest-8-en-3b-ol,Δ8-Cholesterol	Endogenous Metabolite; ROR	Metabolism
	Zymostenol (5a-Cholest-8-en-3b-ol) 是一种 RORγ 激动剂，EC50为1 μM。Zymostenol 是胆固醇生物合成的后期前体。
T15238	Epoprostenol sodium Prostaglandin I2 sodium salt,Prostacyclin sodium salt,Flolan	Others	Others
	Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation.
T13461	(+)-Cloprostenol D-Cloprostenol	Others	Others
	(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.
T20778	Epoprostenol U 53217,U 53,217,U-53,217
	Epoprostenol, a prostaglandin, is a powerful vasodilator. It inhibits platelet aggregation.
T37230	(+)-5-trans Cloprostenol
	Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster.
T37813	Fluprostenol methyl ester
	Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. CAY10532 is a methyl ester analog of fluprostenol.
T20592	Cloprostenol Estrofan,Oestrophan
	Cloprostenol is a synthetic analogue of prostaglandin.
T38115	Fluprostenol serinol amide
	2-arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to form PG 2-glyceryl esters. Fluprostenol serinol amide (Flu-SA) is a stable analog of PGF2α 2-glyceryl ester that has much greater stability. The biological activity of Flu-SA has not yet...
T37929	14-dehydro Zymostenol
	14-dehydro Zymostenol is a precursor to cholesterol .1It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 μM.2 1.Lutsky, B.N., and Schroepfer, G.J., Jr.Studies on the enzymic conversion of 5α-cholesta-8,14-dien-3β-ol to cholesterolJ. Biol. Chem.245(23)6449-6455(1970) 2.Hubler, Z., Allimuthu, D., Bederman, I., et al.Accumulation of 8,9-unsaturated sterols drives oligodendrocyte f...
T29245	(+)-Cloprostenol sodium D-Cloprostenol,D-Cloprostenol sodium salt
	(+) - cloprostenol sodium is a kind of water-soluble prostaglandin F2 α ( PGF2 α) Analogues. It is an FP receptor agonist and a potent luteinizing agent in rats and hamsters.

化合物

(+)-Fluprostenol

Cat.No: T21224

Synonym: Fluprostenol, (+)-,Travoprost acid,AL-5848,曲伏前列素酸

Target: Prostaglandin Receptor

Cloprostenol sodium salt

Cat.No: T5847

Synonym: ICI 80996 sodium salt,DL-Cloprostenol sodium,氯前列烯醇钠,氯前列烯醇纳,Cloprostenol sodium

Target: Prostaglandin Receptor

(+)-Cloprostenol methyl ester

Cat.No: T37231

Cloprostenol isopropyl ester

Cat.No: T29246

Synonym: (+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester,(+)-Cloprostenol isopropyl ester

Cat.No: T32977

Cat.No: T35321

Synonym: delta(8)-Cholestenol,5a-Cholest-8-en-3b-ol,Δ8-Cholesterol

Target: Endogenous Metabolite, ROR

Epoprostenol sodium

Cat.No: T15238

Synonym: Prostaglandin I2 sodium salt,Prostacyclin sodium salt,Flolan

Target: Others

(+)-Cloprostenol

Cat.No: T13461

Synonym: D-Cloprostenol

Target: Others

Cat.No: T20778

Synonym: U 53217,U 53,217,U-53,217

(+)-5-trans Cloprostenol

Cat.No: T37230

Fluprostenol methyl ester

Cat.No: T37813

Cat.No: T20592

Synonym: Estrofan,Oestrophan

Fluprostenol serinol amide

Cat.No: T38115

14-dehydro Zymostenol

Cat.No: T37929

(+)-Cloprostenol sodium

Cat.No: T29245

Synonym: D-Cloprostenol,D-Cloprostenol sodium salt

Cat. No.	Product Name	Target	Signaling Pathways
TN1120	Osthenol	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Osthenol 是一种前酰化香豆素，从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用，IC50=0.74 µM，对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
TN7070	Ergostenol delta8(14)-Ergostenol,alpha-Ergostenol,菜油甾醇,Ergost-8(14)-en-3beta-ol	Others	Others
	Ergostenol (Ergost-8(14)-en-3beta-ol) 是一种生物前体和维生素 D2 的维生素原。
T13503	31-Norlanostenol	Others	Others
	31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor.

天然产物

Cat.No: TN1120

Target: MAO, Monoamine Oxidase

Cat.No: TN7070

Synonym: delta8(14)-Ergostenol,alpha-Ergostenol,菜油甾醇,Ergost-8(14)-en-3beta-ol

Target: Others

31-Norlanostenol

Cat.No: T13503

Target: Others

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