Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1308 |
Orphenadrine hydrochloride
Mebedrol,Mephenamin,盐酸邻甲苯海拉明 |
Sodium Channel; NMDAR; Norepinephrine; iGluR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience |
Orphenadrine hydrochloride (Mephenamin) 是一种非竞争性的NMDA 受体拮抗剂, Ki=6.0 ± 0.7 μM。 | |||
T71537 | Tofenacin hydrochloride | ||
Tofenacin hydrochloride is an antidepressant drug with a tricyclic-like structure. It acts as a serotonin-norepinephrine reuptake inhibitor, and based on its close relation to orphenadrine, may also possess anticholinergic and antihistamine properties. Tofenacin is also the major active metabolite of orphenadrine and likely plays a role in its beneficial effects against depressive symptoms seen in Parkinson's disease patients. |