Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19930 |
Nitrosoglutathione
S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO |
RAAS; NO Synthase | Endocrinology/Hormones; Immunology/Inflammation |
Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体,是大鼠酒精脱氢酶III 类同工酶的底物,能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。 | |||
T6901 |
N6022
|
GSNOR | Metabolism |
N6022 是选择性可逆的S-Nitrosoglutathione reductase 抑制剂,IC50=8 nM。 | |||
T26955 |
Cavosonstat
N91115,N 91115,N-91115 |
GSNOR; CFTR | Membrane transporter/Ion channel; Metabolism |
Cavosonstat (N91115) 是一种口服活性 S-亚硝基谷胱甘肽还原酶(GSNOR)抑制剂,可促进囊性纤维化跨膜传导调节器(CFTR)成熟和质膜稳定。 | |||
T28837 |
SPL-334
SPL334 |
||
SPL-334 is an inhibitor of S-nitrosoglutathione reductase. | |||
T35988 |
CAY10564
|
||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10564 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.0, ... | |||
T35989 |
CAY10565
|
||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0,... | |||
T35987 |
CAY10563
CAY10563 |
||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10563 is a member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.... |