3
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77631 |
Enpp/Carbonic anhydrase-IN-2
|
Apoptosis; PDE; Carbonic Anhydrase | Apoptosis; Metabolism |
Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells. | |||
T67775 |
Enpp/Carbonic anhydrase-IN-1
|
PDE; Carbonic Anhydrase | Metabolism |
Enpp/Carbonic anhydrase-IN-1 (compound 1e) 是有效的 Enpp 和 carbonic anhydrase 抑制剂。Enpp/Carbonic anhydrase-IN-1抑制 NPP1、NPP2、NPP3、CA-II、CA-IX 的 IC50 值分别 1.36、1.35、3.00、0.88、1.02 µM。Enpp/Carbonic anhydrase-IN-1 选择性抑制癌细胞的增殖,对正常细胞毒性较低。 | |||
T72164 | Enpp/Carbonic anhydrase-IN-2 | ||
Enpp/Carbonic anhydrase-IN-2 是一种有效的 Enpp 和 carbonic anhydrase 抑制剂,对 NPP1、NPP2、NPP3、CA-IX, CA-XII 的 IC50值分别 1.13、 1.07、 0.74、 0.33、 0.68。Enpp/Carbonic anhydrase-IN-2 对癌细胞具有抗增殖活性,对正常细胞具有低细胞毒性。Enpp/Carbonic anhydrase-IN-2 诱导细胞凋亡 (Apoptosis)。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02778 |
ENPP2 Protein, Human, Recombinant (His)
ATX,ectonucleotide pyrophosphatase/phosphodiesterase 2 |
Human | HEK293 Cells |
ENPP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is AAH34961.1. | |||
TMPY-00463 |
ENPP2 Protein, Cynomolgus, Recombinant (His)
ENPP2,ectonucleotide pyrophosphatase/phosp... |
Cynomolgus | HEK293 Cells |
ENPP2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is XP_005564040.1. | |||
TMPY-02055 |
ENPP2 Protein, Mouse, Recombinant (His)
PD-Ialpha,Pdnp2,ectonucleotide pyrophosphatase/phos... |
Mouse | HEK293 Cells |
ENPP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is Q9R1E6-1. |