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Cat. No. Product Name Target Signaling Pathways
T11205 ent-Ezetimibe

ent-SCH 58235,ENT-依折麦布

Others Others
ent-Ezetimibe (ent-SCH 58235) 是 Ezetimibe 的 RRS 型对映体。其中Ezetimibe 是一种胆固醇吸收 (cholesterol-absorption) 抑制剂,是NPC1L1抑制剂,也是有效的Nrf2激活剂。
T1593 Ezetimibe

依泽替米贝,SCH 58235

Others; Nrf2; NPC1L1; Autophagy Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
Ezetimibe (SCH 58235) 是一种膳食胆固醇吸收抑制剂。它是一种NPC1L1抑制剂,是有效的Nrf2激活剂。
T11250 Ezetimibe-d4

SCH 58235 D4

Others Others
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
T70849 AZD-4121

AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.
T70848 AZD-4121 tert-butylammonium

AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.
T11003 Desfluoro-ezetimibe

Others Others
Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective Nrf2 activator.
T11251 Ezetimibe ketone

EZM-K

Nrf2; NPC1L1 Immunology/Inflammation; Membrane transporter/Ion channel
Ezetimibe, a compound known as a Niemann-Pick C1-like1 (NPC1L1) inhibitor and a potent Nrf2 activator, effectively inhibits cholesterol absorption. Additionally, Ezetimibe ketone (EZM-K) represents a phase-I metabolite of Ezetimibe.
T16322 Nicodicosapent

Others Others
Nicodicosapent is a fatty acid niacin conjugate. It is also an inhibitor of the sterol regulatory element-binding protein (SREBP). The sterol regulatory element-binding protein (SREBP) is a key regulator of cholesterol metabolism proteins such as PCSK9, H

化合物

ent-Ezetimibe
Cat.No: T11205
Synonym: ent-SCH 58235,ENT-依折麦布
Target: Others
Ezetimibe
Cat.No: T1593
Synonym: 依泽替米贝,SCH 58235
Target: Others, Nrf2, NPC1L1, Autophagy
Ezetimibe-d4
Cat.No: T11250
Synonym: SCH 58235 D4
Target: Others
AZD-4121
Cat.No: T70849
Synonym:
Target:
AZD-4121 tert-butylammonium
Cat.No: T70848
Synonym:
Target:
Desfluoro-ezetimibe
Cat.No: T11003
Synonym:
Target: Others
Ezetimibe ketone
Cat.No: T11251
Synonym: EZM-K
Target: Nrf2, NPC1L1
Nicodicosapent
Cat.No: T16322
Synonym:
Target: Others
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