首页工具

登录

搜索结果

Search Results for " nmt "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T67919	NMT-IN-1	Others	Others
	NMT-IN-1 是一种有效的 N-肉豆豆酰转移酶(NMT) 抑制剂，对 TbNMT 的 IC50为31μM ，对 hNMT 的 IC50为66μM。NMT-IN-1是治疗非洲锥虫病的潜在化合物。
T27135	DDD85646 DDD 85646,DDD-85646	Parasite	Microbiology/Virology
	DDD85646 是 T. brucei N-myristoyltransferase 的抑制剂，Ki 为 1.44 nM，IC50 为 2 nM，EC50 为 2 nM。 hNMT 的 IC50 为 4 nM。
T8760	NNMTi 5-Amino-1-methylquinolinium	Others	Others
	NNMTi (5-Amino-1-methylquinolinium) 是烟酰胺 N -甲基转移酶的抑制剂 (IC50=1.2 μM)，可选择性地结合 NNMT 底物结合位点残基。它能诱导体外成肌细胞分化，提高老年小鼠肌肉干细胞融合和再生能力。
T63493	NNMT-IN-2
	NNMT-IN-2 是一种很强的NNMT 抑制剂 (IC50: 3.7 nM)。
T38437	NMTCA N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline
	NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid utilized as an endogenous nitrosation indicator in gas chromatography-thermal energy analysis.
T81661	NNMT-IN-4
	NNMT-IN-4（compound 38），一种选择性、非竞争性且具有膜通透性的烟酰胺N-甲基转移酶（NNMT）抑制剂，在体外生化及细胞实验中的IC50值为42 nM和38 nM。该抑制剂展现出良好的PK/PD关系和安全性，同时具备优秀的口服生物利用度和药物制剂性质，适合作为NNMT活性研究的体内化学探针。
T81432	PNMT-IN-1
	PNMT-IN-1（Inhibitor 4）是一种高特异性的PNMT抑制剂，具有1.2 nM的Ki值和81 nM的IC50值。它对DNMT1和DNMT3b也表现出活性，IC50值分别为61 μM和17 μM，并且对肾上腺素具有拮抗效果。PNMT-IN-1属于第二代抑制剂。
T64189	NNMT-IN-3
	NNMT-IN-3 (compound 14) 是一种有效的、选择性的烟酰胺 N-甲基转移酶 (NNMT) 抑制剂，在无细胞和基于细胞的实验中的 IC50 值分别为 1.1 nM 和 0.4 μM。NNMT-IN-3 能够用于肥胖、癌症、II 型糖尿病及骨骼肌减少症等疾病的研究。
T63859	DNMT3A-IN-1
	DNMT3A-IN-1 是选择性的、有效的 DNMT3A 抑制剂。 DNMT3A-IN-1 对 DNMT3A 表现出抑制活性，其 KI 的范围为 9.16-18.85 μM (AdoMet) 和 11.37-23.34 μM (poly dI-dC)。
T23477	tris(dibenzylideneacetone)dipalladium Tris DBA,三(二亚苄基丙酮)二钯	Others	Others
	tris(dibenzylideneacetone)dipalladium (Tris DBA) 是一种 N-myristoyltransferase-1 (NMT-1) 抑制剂。
T63788	PCLX-001	Others	Others
	PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates anti-tumor effects and effectively inhibits the early signaling of B-cell receptor (BCR). Consequently, PCLX-001 is a valuable tool for researching B-cell malignancies [1] [2].
T27831	Lifibrate
	Lifibrate is an inhibitor of cholinephosphotransferase (CPT), phosphatidyl-N,N-dimethylethanolamine N-methyltransferase (PDE-NMT), and phosphatidyl-N-methylethanolamine N-methyltransferase (PME-NMT).
T28701	SC-58272 SC58272
	SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.
T27127	DCAT Maleate DCAT
	DCAT Maleate is an inhibitor of N-methyl transferases (NMT). DCAT Maleate methylate non-methylated pre-neurotoxins to prevent the formation of Parkinson's syndrome neurotoxins.
T68562	FTR-1335
	FTR1335 is a CaNMT inhibitor (IC50 = 0.49 nM) with good fungal selectivity. CaNMT inhibitors are fungicidal and show antifungal activity against Candida (especially fluconazole-resistant strains). They function by inhibiting N-myristoyltransferase (NMT), which catalyzes the transfer of a C14 fatty acif from myristoyl-CoA to the N-terminal of glycine in many fungal proteins. Without this process, fungi can die. This process also occurs in humans, and as such selectivity is an important characteri...

化合物

Cat.No: T67919

Target: Others

Cat.No: T27135

Synonym: DDD 85646,DDD-85646

Target: Parasite

Cat.No: T8760

Synonym: 5-Amino-1-methylquinolinium

Target: Others

Cat.No: T63493

Cat.No: T38437

Synonym: N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline

Cat.No: T81661

Cat.No: T81432

Cat.No: T64189

Cat.No: T63859

tris(dibenzylideneacetone)dipalladium

Cat.No: T23477

Synonym: Tris DBA,三(二亚苄基丙酮)二钯

Target: Others

Cat.No: T63788

Target: Others

Cat.No: T27831

Cat.No: T28701

Synonym: SC58272

Cat.No: T27127

Synonym: DCAT

Cat.No: T68562

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼