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Search Results for " nix "

Targets Recommended: PPAR

16

抑制剂 & 化合物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T2269	Pirinixic Acid Wy-14643,NSC 310038,匹立尼酸	PPAR	DNA Damage/DNA Repair; Metabolism
	Pirinixic Acid (NSC 310038) 是一种过氧化物酶体增殖剂，可激活特定的过氧化物酶体增殖物激活受体 (PPAR)。它对鼠的PPARα和 PPARγ 的EC50值分别为 0.63 和 32 μM，对人的PPARα、PPARγ 和 PPARδ 的EC50值分别为 5.0 、60 和 35 μM。
T1209	Flunixin meglumine Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺	COX	Immunology/Inflammation; Neuroscience
	Flunixin meglumine (Banamine) 是一种环氧合酶抑制剂，具有抗炎和解热活性。
T4542	Clonixin Clonixic acid,氯尼辛	Others	Others
	Clonixin (Clonixic acid) 是一种非甾体抗炎药，具有口服活性。
T20869	Flunixin Sch14714,Flunixinum,Flunixine,Sch 14714,Flunixino,Sch-14714
	Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.
T80424	Phoenixin-20 TFA PNX-20 TFA	Epigenetic Reader Domain	Chromatin/Epigenetic
	Phoenixin-20 (TFA) (PNX-20 (TFA)) 是一种在脊椎动物中发挥激素作用的生物活性肽，能够激活下丘脑-垂体-性腺轴，从而调控哺乳类动物的生殖机能。此外，该肽通过CREB-PGC-1α途径，增强神经元的线粒体生物生成。
T80422	Phoenixin-14 PNX-14	GNRH Receptor	GPCR/G Protein
	Phoenixin-14 (PNX-14) 是一种具有内源性活性的异构体，能通过激活AHA GnRH系统发挥抗焦虑效果，并抑制缺血/再灌注所诱导的小胶质细胞毒性。
T69662	Inixaciclib
	Inixaciclib 是一种有效的CDK 抑制剂，可用于抗癌研究。
T37209	5-hydroxy Flunixin
	5-hydroxy Flunixin is a metabolite of the COX inhibitor flunixin .1 1.Daeseleire, E., Mortier, L., De Ruyck, H., et al.Determination of flunixin and ketoprofen in milk by liquid chromatography-tandem mass spectrometryAnal. Chim. Acta488(1)25-34(2003)
T30138	Aronixil
	Aronixil is a biochemical.
T13821	Pirinixil BR-931,匹立昔尔	Others	Others
	Pirinixil is a hypolipidemic low toxicity agent.
TP2280	ovalbumin (324-338) [Gallus gallus]/[Coturnix coturnix]	Others	Others
	Ovalbumin is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin is an important protein in several different areas of research, including general studies of protein structure and properties. Ovalbumin is used for studies
T81485	Phoenixin-14 TFA PNX-14 TFA
	Phoenixin-14 (PNX-14) TFA 是具抗焦虑、心脏保护及神经保护效果的穿透大脑屏障神经肽。它通过上调GnRH受体mRNA调控垂体促性腺激素分泌，并促进胰岛素释放。此外，Phoenixin-14 TFA保护小鼠免受缺血/再灌注(IR)伤害，通过降低ROS、提高GSH减缓氧化应激。
T32843	Lodinixil
	Lodinixil is a bioactive chemical.
T15561	Imanixil HOE-402(free base)	Others	Others
	Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis development.
T27633	Isonixin Nixyn,Isonixine
	Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.
T80423	Phoenixin-20 PNX-20	Epigenetic Reader Domain	Chromatin/Epigenetic
	Phoenixin-20（PNX-20）为脊椎动物内具激素样生物活性肽，能激活下丘脑-垂体-性腺轴，调控哺乳类生殖过程。该肽通过CREB-PGC-1α途径增进神经元线粒体生物发生。

化合物

Cat.No: T2269

Synonym: Wy-14643,NSC 310038,匹立尼酸

Target: PPAR

Flunixin meglumine

Cat.No: T1209

Synonym: Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺

Target: COX

Cat.No: T4542

Synonym: Clonixic acid,氯尼辛

Target: Others

Cat.No: T20869

Synonym: Sch14714,Flunixinum,Flunixine,Sch 14714,Flunixino,Sch-14714

Phoenixin-20 TFA

Cat.No: T80424

Synonym: PNX-20 TFA

Target: Epigenetic Reader Domain

Cat.No: T80422

Synonym: PNX-14

Target: GNRH Receptor

Cat.No: T69662

5-hydroxy Flunixin

Cat.No: T37209

Cat.No: T30138

Cat.No: T13821

Synonym: BR-931,匹立昔尔

Target: Others

ovalbumin (324-338) [Gallus gallus]/[Coturnix coturnix]

Cat.No: TP2280

Target: Others

Phoenixin-14 TFA

Cat.No: T81485

Synonym: PNX-14 TFA

Cat.No: T32843

Cat.No: T15561

Synonym: HOE-402(free base)

Target: Others

Cat.No: T27633

Synonym: Nixyn,Isonixine

Cat.No: T80423

Synonym: PNX-20

Target: Epigenetic Reader Domain

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02376	BNIP3L Protein, Human, Recombinant BCL2/adenovirus E1B 19kDa interacting protein 3-like,NIX...	Human	E. coli
	The deletion of BNIP3L results in retention of mitochondria during lens fiber cell remodeling, and that deletion of BNIP3L also results in the retention of endoplasmic reticulum and Golgi apparatus. BNIP3L localizes to the endoplasmic reticulum and Golgi apparatus of wild-type newborn mouse lenses and is contained within mitochondria, endoplasmic reticulum and Golgi apparatus isolated from adult mouse liver. As the cells become packed with keratin bundles, Bnip3L expression triggers mitophagy to...
TMPH-00433	Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)	Coturnix coturnix japonica	E. coli
	Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00434	Ovomucoid Protein, Coturnix delegorguei, Recombinant (His & Myc & SUMO)	Coturnix delegorguei	E. coli
	Ovomucoid Protein, Coturnix delegorguei, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-02536	BNIP3 Protein, Mouse, Recombinant (Cell-Free, His) Bnip3,BCL2/adenovirus E1B 19 kDa protein-interacting protein...	Mouse	in vitro E. coli expression system
	Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP...
TMPH-02537	BNIP3 Protein, Mouse, Recombinant (His) Bnip3,Nip3,BCL2/adenovirus E1B 19 kDa protein-interacting pr...	Mouse	E. coli
	Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP...

重组蛋白

BNIP3L Protein, Human, Recombinant

Cat.No: TMPY-02376

Species: Human

Expression System: E. coli

Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)

Cat.No: TMPH-00433

Species: Coturnix coturnix japonica

Expression System: E. coli

Ovomucoid Protein, Coturnix delegorguei, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00434

Species: Coturnix delegorguei

Expression System: E. coli

BNIP3 Protein, Mouse, Recombinant (Cell-Free, His)

Cat.No: TMPH-02536

Species: Mouse

Expression System: in vitro E. coli expression system

BNIP3 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02537

Species: Mouse

Expression System: E. coli

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