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Search Results for " mrt6 "

Targets Recommended: Autophagy

6

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T6899	MRT68921 MRT68921 HCl	Autophagy	Autophagy
	MRT68921 有效抑制 ULK1和 ULK2，IC50值分别为 2.9 nM 和 1.1 nM。
T5162	MRT67307 HCl (1190378-57-4(free base)) 盐酸MRT67307	IκB/IKK; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; NF-κB; PI3K/Akt/mTOR signaling
	MRT67307 HCl (1190378-57-4(free base)) 是 TBK1、MARK1-4、IKKε 和 NUAK1 的激酶抑制剂（IC50 分别为 19、27-52、160 和 230 nM）。
T9142	MRT68921 dihydrochloride	Autophagy	Autophagy
	MRT68921 dihydrochloride 有效抑制ULK1和ULK2，IC50值分别为 2.9 nM 和 1.1 nM。
T0097	MRT67307 MRT67307 HCl	IκB/IKK; Autophagy	Autophagy; NF-κB
	MRT67307 是一种IKKε和TBK-1的双抑制剂，IC50分别为 160 和 19 nM。它抑制细胞自噬，也可抑制ULK1和ULK2，IC50分别为 45 和 38 nM。
T5356	MRT68921 HCl 盐酸MRT68921	Autophagy	Autophagy
	MRT68921 HCl 是 ULK1 和 ULK2 的有效抑制剂（IC50 分别为 2.9 和 1.1 nM）。
T23028	MRT67307 HCl (1190378-57-4 free base) MRT67307 HCl	Others	Others
	MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it is a salt inducible kinase (SIK) inhibitor with IC50 value of 250, 67 and 430nM for SIK1, SIK2 and SIK3, respectively.<br />SIKs prevent the formation of regulatory macrophages and their inhibition induces increasing in some markers of regulatory macrophages, such as IL-10 and oth...

化合物

Cat.No: T6899

Synonym: MRT68921 HCl

Target: Autophagy

MRT67307 HCl (1190378-57-4(free base))

Cat.No: T5162

Synonym: 盐酸MRT67307

Target: IκB/IKK, AMPK, Autophagy

MRT68921 dihydrochloride

Cat.No: T9142

Target: Autophagy

Cat.No: T0097

Synonym: MRT67307 HCl

Target: IκB/IKK, Autophagy

Cat.No: T5356

Synonym: 盐酸MRT68921

Target: Autophagy

MRT67307 HCl (1190378-57-4 free base)

Cat.No: T23028

Synonym: MRT67307 HCl

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc) GLUR6,EAA4,MRT6,GLR6,glu...	Human	HEK293 Cells
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...

重组蛋白

GRIK2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04318

Species: Human

Expression System: HEK293 Cells

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