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Search Results for " mp2 "

Targets Recommended: Others

11

抑制剂 & 化合物

19

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2193	Myelopeptide-2 (MP-2)	Others	Others
	Myelopeptide-2 (MP-2) with the sequence Leu-Val-Val-Tyr-Pro-Trp is originally isolated from the supernatant of porcine bone marrow cell culture and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from H
T69979	Risvodetinib
	Risvodetinib是一种高效的蛋白酪氨酸激酶抑制剂，涉及抑制Abelson蛋白激酶(c-Abl1、c-Abl2和c-kit)的活性。
T24494	MP265 S-(4-氯苄基)氯化异硫脲,MP-265,MP 265	Others	Others
	MP265 破坏 MreB 细胞骨架并具有抗增殖作用。
T61326	AIMP2-DX2-IN-1	Others	Others
	AIMP2-DX2-IN-1 是一种有效的 AIMP2-DX2 抑制剂，具有潜在的抗肿瘤活性，可用于研究淋巴癌。
T1857	TMP269	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	TMP269 是一种有效的特异性 IIa 类 HDAC 抑制剂，分别抑制 HDAC 4/HDAC 5/HDAC 7/HDAC 9，IC50值分别为 157 nM，97 nM，43 nM 和 23 nM。
T61271	MMP2-IN-3	MMP	Proteases/Proteasome
	MMP2-IN-3是一种有效的基质金属蛋白酶（MMP-2）抑制剂（ IC50 值：31 μM）。MMP2-IN-3 抑制 MMP-9 和 MMP-8 ，其 IC50 分别为 26.6 和 32 μM。
T62685	IMP2-IN-2
	IMP2-IN-2 是一种有效的、选择性的 IMP2 抑制剂，抑制 IMP2 与 RNA_A 和 RNA_B 相互作用的 IC50 值分别为 120.9 μM 和 236.7 μM。IMP2-IN-2 能够用于研究癌症。
T60551	MMP2-IN-2
	MMP2-IN-2 (化合物 42) 是一种有效且选择性的MMP-2(基质金属蛋白酶)抑制剂，其IC50值为 4.2 μM。它对MMP-13、MMP-9和MMP-8也具有抑制活性，IC50值分别为 12、23.3 和 25 μM。
T82851	BMP2-derived peptide
	BMP2-derived peptide为BMP-2第73至92位氨基酸序列的功能性基序，具有促进骨髓基质细胞(BMSCs)成骨分化及骨再生的作用。
T61946	IMP2-IN-1
	IMP2-IN-1 (compound 4) 是有效的IMP2抑制剂，对 IMP2 RNA 的IC50为 81.3-127.5 μM。IMP2-IN-1 降低 SW480 细胞中 IMP2 水平。IMP2-IN-1 显著抑制分化和未分化 Huh7 细胞的活力。
T60845	MMP2-IN-1
	MMP2-IN-1 通过阻滞细胞周期和诱导细胞凋亡，在部分癌细胞中显示出显着的抗增殖活性。MMP2-IN-1 是MMP2 的中度强效抑制剂 (IC50 = 6.8 μM)。

化合物

Myelopeptide-2 (MP-2)

Cat.No: TP2193

Target: Others

Cat.No: T69979

Cat.No: T24494

Synonym: S-(4-氯苄基)氯化异硫脲,MP-265,MP 265

Target: Others

Cat.No: T61326

Target: Others

Cat.No: T1857

Target: HDAC

Cat.No: T61271

Target: MMP

Cat.No: T62685

Cat.No: T60551

BMP2-derived peptide

Cat.No: T82851

Cat.No: T61946

Cat.No: T60845

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01563	PMP2 Protein, Human, Recombinant (His) MP2,FABP8,peripheral myelin protein 2<...	Human	E. coli
	Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ...
TMPH-00831	PMP2 Protein, Horse, Recombinant (His & SUMO)	Horse	E. coli
	May play a role in lipid transport protein in Schwann cells. May bind cholesterol. PMP2 Protein, Horse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is P0C6G6.
TMPH-00927	AIMP2 Protein, Human, Recombinant (His) Protein JTV-1,Aminoacyl tRNA synthase complex-inter...	Human	E. coli
	AIMP2 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04115	LAMP2 Protein, Human, Recombinant (His) lysosomal-associated membrane protein 2,LAMP	Human	HEK293 Cells
	LAMP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.77 kDa and the accession number is P13473-2.
TMPK-01503	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi) Macropain chain 7,LMP-2,RING12,L<...	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01533	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi) MHC,LMP2,RING12,PSMB9,Macropain c...	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01542	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi) RMF,PSMB9,Proteasome chain 7,RING12,LMP	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPY-00499	TMP21 Protein, Human, Recombinant (mFc) Tmp-21-I,p23,S31III125,T...	Human	HEK293 Cells
	TMED10 disrupts the complex formation between TGF-beta type I (also termed ALK5) and type II receptors (TbetaRII). Misexpression studies revealed that TMED10 attenuated TGF-beta-mediated signaling. A 20-amino acid-long region from Thr(91) to Glu(110) within the extracellular region of TMED10 was found to be crucial for TMED10 interaction with both ALK5 and TbetaRII. Synthetic peptides corresponding to this region inhibit both TGF-beta-induced Smad2 phosphorylation and Smad-dependent transcriptio...
TMPK-01498	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi) Proteasome chain 7,MHC,RING12,RMF,LMP2...	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPH-03399	VAMP2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Involved in the targeting and/or fusion of transport vesicles to their target membrane. Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. VAMP2 Protein, Rat, Recombina...
TMPY-03685	LAMP2 Protein, Cynomolgus, Recombinant (His) lysosomal-associated membrane protein 2	Cynomolgus	HEK293 Cells
	LAMP2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is G7Q3L7.
TMPY-02382	LAMP2 Protein, Mouse, Recombinant (His) Mac3,LGP-B,CD107b,LampII,Lamp-2a,...	Mouse	HEK293 Cells
	LAMP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.6 kDa and the accession number is P17047-1.
TMPK-01502	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated PSMB9,LMP2,Macropain chain 7,MHC,Proteasom...	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01535	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) Macropain chain 7,LMP2,Proteasome chain 7,...	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPH-00544	Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO)	EBV	E. coli
	Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.6 kDa and the accession number is P13285.
TMPH-03350	Pmp22 Protein, Rat, Recombinant (His)	Rat	E. coli
	Might be involved in growth regulation, and in myelinization in the peripheral nervous system. Pmp22 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P25094.
TMPK-01534	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) RING12,PSMB9,Proteasome chain 7,RMF,LMP-	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPH-03035	M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)	Myrmecia pilosula	Baculovirus Insect Cells
	Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 uM). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus. In addition, intraplant...
TMPK-01530	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,LMP-2,PSMB9,LMP2,Mac...	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...

重组蛋白

PMP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01563

Species: Human

Expression System: E. coli

PMP2 Protein, Horse, Recombinant (His & SUMO)

Cat.No: TMPH-00831

Species: Horse

Expression System: E. coli

AIMP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-00927

Species: Human

Expression System: E. coli

LAMP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04115

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01503

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01533

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01542

Species: Human

Expression System: HEK293 Cells

TMP21 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00499

Species: Human

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01498

Species: Human

Expression System: HEK293 Cells

VAMP2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03399

Species: Rat

Expression System: E. coli

LAMP2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03685

Species: Cynomolgus

Expression System: HEK293 Cells

LAMP2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02382

Species: Mouse

Expression System: HEK293 Cells

HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01502

Species: Human

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01535

Species: Human & Mouse

Expression System: HEK293 Cells

Epstein-Barr virus (strain B95-8) LMP2 Protein (His & SUMO)

Cat.No: TMPH-00544

Species: EBV

Expression System: E. coli

Pmp22 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03350

Species: Rat

Expression System: E. coli

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01534

Species: Human & Mouse

Expression System: HEK293 Cells

M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His)

Cat.No: TMPH-03035

Species: Myrmecia pilosula

Expression System: Baculovirus Insect Cells

HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01530

Species: Human

Expression System: HEK293 Cells

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