Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1279 |
Vilazodone
维拉佐酮,SB659746A,EMD 68843 |
5-HT Receptor; Serotonin Transporter | GPCR/G Protein; Neuroscience |
Vilazodone (SB659746A) 是一种可口服的选择性 5 -羟色胺再摄取抑制剂 (SSRI) 和部分5-HT1A 受体激动剂。它有抗抑郁作用,可用于抑郁症和情绪性疾病的研究。 | |||
T41173 |
FAM-DEALAHypYIPMDDDFQLRSF
|
||
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD. | |||
T64317 |
ZZL-7
|
Serotonin Transporter | Neuroscience |
ZZL-7是一种起效快的抗抑郁药。ZZL-7破坏中缝背核(DRN)神经元一氧化氮合酶(nNOS)和血清素转运蛋白(SERT)之间的相互作用。ZZL-7可以很容易地穿过血脑屏障。ZZL-7在重度抑郁症(MDD)中具有研究价值。 | |||
T22453 |
Venlafaxine
Wy 45030,文拉法辛 |
Serotonin Transporter | Neuroscience |
Venlafaxine (Wy 45030) 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂,具有抗抑郁活性。 | |||
T69063 | Orvepitant | ||
Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia. | |||
T68579 | Fluvoxamine acid | ||
Fluvoxamine acid is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD), and is also used to treat major depressive disorder (MDD), and anxiety disorders such as panic disorder and post-traumatic stress disorder (PTSD). |