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34

抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
T80665	Leu-Val L-leucyl-L-valine	Parasite; Antifungal	Microbiology/Virology
	Leu-Val (L-leucyl-L-valine) 是一种新型有效的二肽，具有抗菌和抗疟活性。
TP2305	pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val	Others	Others
	pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val 是一种肽。
TP1308	Suc-Leu-Leu-Val-Tyr-AMC
	Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases.
T32678	Leucyl-valyl-isoleucinamide Leu-val-ile-NH2,Leu-val-ile-amide
	Leucyl-valyl-isoleucinamide is a oligopeptide.
TP2361	Abecomotide Lys-thr-val-asn-glu-leu-gln-asn-leu
	Abecomotide is a bioactive chemical.
T34780	Taltsv Tyr-asn-leu-thr-ser-val
	Taltsv is a bioactive peptide.
T78185	Ac-PLVE-FMK Ac-Pro-Leu-Val-Glu(OMe)-CH2F	Others	Others
	Ac-PLVE-FMK（Ac-Pro-Leu-Val-Glu(OMe)-CH2F），一种四肽基m-FMK化合物，具有Cats抑制作用，常用于癌症研究。
T78186	Ac-VLPE-FMK Ac-Val-Leu-Pro-Glu(OMe)-CH2F
	Ac-VLPE-FMK为一种四肽基单氟甲基酮(m-FMK)，兼作Cat-B及Cat-L抑制剂，适用于癌症侵袭性研究。
T38130	Z-LVG-CHN2 Z-Leu-Val-Gly-diazomethylketone
	The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.
T25683	Leucomyosuppressin p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2
	Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T25098	Antiflammin P2 Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu
	Antiflammin P2 is a nonapeptide fragment of lipocortin I which has no phospholipase A2 inhibitory and anti-inflammatory activity.
T25862	Neomyosuppressin Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS
	Neomyosuppressin is a myoinhibiting neuropeptide isolated from the grey fleshfly, Neobellieria bullata and Drosophila.
TP2371	Asudemotide Glu-tyr-tyr-glu-leu-phe-val-asn-ile
	Asudemotide is a bioactive chemical.
T31808	Flrlamide, manduca Glu-asp-val-val-his-ser-phe-leu-arg-phe-Nh2,Pedvvhsflrf-NH2,Masflrfamide I
	Flrlamide, manduca is a bioactive peptide extracted from the central nervous system of Manduca sexta.
TP2455	Locustapyrokinin II Pglu-ser-val-pro-thr-phe-thr-pro-arg-leu-NH2
	Locustapyrokinin II is a member of the FXPRL-amide peptide family isolated from Locusta migratoria.
T83745	RYTVELA TFA H-Arg-Tyr-Thr-Val-Glu-Leu-Ala-OH
	RYTVELA是一种基于多肽拮抗剂的衍生物，针对白细胞介素-1受体1（IL-1R1），包含全部的L-氨基酸。
T26079	RI 61 RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61
	RI 61 (sumatriptan succinate) is utilized in the therapy of migraine, cluster headaches, new daily persistent headache, and cyclic vomiting syndrome.
TP1099	M-2420 Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl
	M-2420 is a fluorogenic substrate designed specifically for the β-secretase site found in the Swedish mutation of the amyloid precursor protein (APP).
T36405	Pro-Adrenomedullin (153-185), human Pro-Adrenomedullin (153-185), human,H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH
	Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system...
T24901	Troponin I (104-115) Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2,Tni peptide (104-115)
	Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of a heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place.
TP2480	Locustamyotropin Lom-MT,Locustamyotropin I,Lom MT,LomMT,Gly-ala-val-pro-ala-ala-gln-phe-ser-pro-arg-leu-NH2
	Locustamyotropin is a novel peptide isolated from Leucophae maderae; stimulates the spontaneous contractions of the hindgut of Leucophaea maderae.
T76599	Ac-Leu-Val-Lys-Aldehyde
	Ac-Leu-Val-Lys-Aldehyde 是有效的组织蛋白酶 B (cathepsin B) 抑制剂，其 IC50 值为 4 nM。该化合物能显着降低喹啉酸引起的纹状体细胞死亡，并促使 LC3-II 积累。
T82521	D-Val-Leu-Lys-chloromethylketone
	D-Val-Leu-Lys-chloromethylketone，一种含D-Val、Leu和Lys三种氨基酸的多肽类化合物，具有抗凝血功能。
T21760L	COG 133 Acetate COG 133 Acetate(514200-66-9 Free base)	Others	Others
	COG 133 Acetate 是一种肽，序列为 Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-amide .
T21662L	Cadherin Peptide, avian Acetate Cadherin Peptide, avian Acetate (127650-08-2 Free base)	Others	Others
	Cadherin Peptide, avian Acetate 是一种肽，序列为 Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2。钙粘蛋白是一类 1 型跨膜蛋白。
T21582L	Acetyl Angiotensinogen (1-14), porcine Acetate Acetyl Angiotensinogen (1-14), porcine Acetate（66641-26-7 Free base）	Others	Others
	Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽，序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。
T30642	BW 633C BW 633-C,BW633C BW-633-C,BW633-C,BW-633C
	BW 633C is a octapeptide with aminoalcohol (AA) linkage between Leu & Val.
TP2257	Histone-H2A-(107-122)-Ac-OH	Others	Others
	Histone-H2A-(107-122)-Ac-OH is a peptide with the sequence Ac-Gly-Val-Leu-Pro-Asn-Ile-Gln-Ala-Val-Leu-Leu-Pro-Lys-Lys-Thr-Glu-OH, MW= 1762.1. Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
T82142	Hymenistatin I
	Hymenistatin I，一种环八肽[c-(-Pro-Pro-Tyr-Val-Pro-Leu-Ile-ile-Ile-)]，具有免疫抑制活性，影响体液和细胞免疫应答。
TP2256	heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]	Others	Others
	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.
TP2260	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]	Others	Others
	Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the antigen recognition molecules of B cell
TP2270	MHC class II antigen (45-57) [Homo sapiens]	Others	Others
	MHC class II antigen (45-57) [Homo sapiens] is a peptide with the sequence H2N-Asp-Leu-Asp-Lys-Lys-Glu-Thr-Val-Trp-His-Leu-Glu- Glu-OH, MW= 1868.07. MHC (major histocompatibility complex) class II molecules are found only on antigen-presenting cells and l
TP2193	Myelopeptide-2 (MP-2)	Others	Others
	Myelopeptide-2 (MP-2) with the sequence Leu-Val-Val-Tyr-Pro-Trp is originally isolated from the supernatant of porcine bone marrow cell culture and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from H
TP2269	MAP kinase fragment [Multiple species]	Others	Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group.

化合物

Cat.No: T80665

Synonym: L-leucyl-L-valine

Target: Parasite, Antifungal

pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val

Cat.No: TP2305

Target: Others

Suc-Leu-Leu-Val-Tyr-AMC

Cat.No: TP1308

Leucyl-valyl-isoleucinamide

Cat.No: T32678

Synonym: Leu-val-ile-NH2,Leu-val-ile-amide

Cat.No: TP2361

Synonym: Lys-thr-val-asn-glu-leu-gln-asn-leu

Cat.No: T34780

Synonym: Tyr-asn-leu-thr-ser-val

Cat.No: T78185

Synonym: Ac-Pro-Leu-Val-Glu(OMe)-CH2F

Target: Others

Cat.No: T78186

Synonym: Ac-Val-Leu-Pro-Glu(OMe)-CH2F

Cat.No: T38130

Synonym: Z-Leu-Val-Gly-diazomethylketone

Leucomyosuppressin

Cat.No: T25683

Synonym: p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2

Cat.No: T25098

Synonym: Hdmnkvldl,Antiflamin 2,His-asp-met-asn-lys-val-leu-asp-leu

Neomyosuppressin

Cat.No: T25862

Synonym: Thr-asp-val-asp-his-val-phe-leu-arg-phenh2,Dromyosuppressin,Neb-MS

Cat.No: TP2371

Synonym: Glu-tyr-tyr-glu-leu-phe-val-asn-ile

Flrlamide, manduca

Cat.No: T31808

Synonym: Glu-asp-val-val-his-ser-phe-leu-arg-phe-Nh2,Pedvvhsflrf-NH2,Masflrfamide I

Locustapyrokinin II

Cat.No: TP2455

Synonym: Pglu-ser-val-pro-thr-phe-thr-pro-arg-leu-NH2

Cat.No: T83745

Synonym: H-Arg-Tyr-Thr-Val-Glu-Leu-Ala-OH

Cat.No: T26079

Synonym: RI-61,Pro-his-pro-phe-his-leu-phe-val-phe,RI61

Cat.No: TP1099

Synonym: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl

Pro-Adrenomedullin (153-185), human

Cat.No: T36405

Synonym: Pro-Adrenomedullin (153-185), human,H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH

Troponin I (104-115)

Cat.No: T24901

Synonym: Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2,Tni peptide (104-115)

Locustamyotropin

Cat.No: TP2480

Synonym: Lom-MT,Locustamyotropin I,Lom MT,LomMT,Gly-ala-val-pro-ala-ala-gln-phe-ser-pro-arg-leu-NH2

Ac-Leu-Val-Lys-Aldehyde

Cat.No: T76599

D-Val-Leu-Lys-chloromethylketone

Cat.No: T82521

COG 133 Acetate

Cat.No: T21760L

Synonym: COG 133 Acetate(514200-66-9 Free base)

Target: Others

Cadherin Peptide, avian Acetate

Cat.No: T21662L

Synonym: Cadherin Peptide, avian Acetate (127650-08-2 Free base)

Target: Others

Acetyl Angiotensinogen (1-14), porcine Acetate

Cat.No: T21582L

Synonym: Acetyl Angiotensinogen (1-14), porcine Acetate（66641-26-7 Free base）

Target: Others

Cat.No: T30642

Synonym: BW 633-C,BW633C BW-633-C,BW633-C,BW-633C

Histone-H2A-(107-122)-Ac-OH

Cat.No: TP2257

Target: Others

Cat.No: T82142

heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

Cat.No: TP2256

Target: Others

Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens]

Cat.No: TP2260

Target: Others

MHC class II antigen (45-57) [Homo sapiens]

Cat.No: TP2270

Target: Others

Myelopeptide-2 (MP-2)

Cat.No: TP2193

Target: Others

MAP kinase fragment [Multiple species]

Cat.No: TP2269

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6447	Cyclo(Leu-Val)
	Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain.

天然产物

Cyclo(Leu-Val)

Cat.No: TN6447

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