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Cat. No.	Product Name	Target	Signaling Pathways
T0682	Lamivudine GR109714X,BCH-189,拉米夫定	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Lamivudine (BCH-189) 是一种核苷逆转录酶抑制剂，可抑制HIV 逆转录酶1和2 以及乙型肝炎病毒的逆转录酶。
T25609	Lamivudine, (+/-)-trans- Lamivudine specified impurity B
	Lamivudine, (+/-)-trans- is a reverse transcriptase inhibitor and zalcitabine analog. It is used for the treatment of hepatitis B (HBV) and Human Immunodeficiency Virus Type 1 (HIV-1).
T32550	Lamivudine impurity A RS Lamivudine impurity A,Lamivudine specified impurity A
	Lamivudine impurity A RS is a bioactive chemical.
T20591	Lamivudine sulfoxide, (R)- Lamivudine impurity H,GI138870X,GI 138870X,GI-138870X
	Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine. Lamivudine is a potent nucleoside reverse transcriptase inhibitor and antiviral agent used for the treatment of chronic hepatitis B.
T11814	Lamivudine 13C,15N2	Others	Others
	Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
T61427	Lamivudine salicylate
	Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI) that effectively inhibits the reverse transcriptase activity of both HIV 1/2 and hepatitis B virus. Moreover, it demonstrates the ability to penetrate the central nervous system [1] [2].
T2279	Tizoxanide 替唑尼特,Desacetyl-nitazoxanide,TIZ	Antiviral; HIV Protease; Antibacterial; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Tizoxanide (Desacetyl-nitazoxanide) 是 Nitazoxanide 活性代谢物，有抗HIV-1的活性。Nitazoxanide 可抗细菌和多种病毒复制。
T4121	Bicyclol SY801,双环醇	HBV; Autophagy	Autophagy; Microbiology/Virology
	Bicyclol (SY801) 是一种抗肝炎 HBV 和 HCV 药物。
T13574	Besifovir Dipivoxil maleate LB80380 maleate	Others	Others
	Besifovir Dipivoxil (LB80380) maleate is an oral prodrug of LB80317. Besifovir Dipivoxil maleate is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients.
T25023	Alamifovir
	Alamifovir 是一种对乙型肝炎病毒具有特异性的抗病毒药物。它是一种嘌呤核苷酸类似物前药，对野生型和拉米夫定耐药的乙型肝炎病毒具有活性，通过抑制病毒DNA 启动和病毒DNA 包装发挥作用，从而减少HBV 复制。
T14313	Apricitabine AVX754,SPD754	HIV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Apricitabine (SPD754) 是一种具有高选择性和口服活性的HIV-1逆转录酶抑制剂(Ki=0.08μM)，是2′-脱氧-3′-氧-4′-硫代胞苷(dOTC)的(-)对映体。 Apricitabine 对DNA 聚合酶α、β和γ具有抑制作用，Ki 值分别为300μM、12μM 和112.25μM。Apricitabine 在抗逆转录病毒HIV 感染者中显示出良好的抗逆转录病毒治疗效果，具有良好的耐受性和较低的选择性抗性。
T63848	TLR8 agonist 4
	TLR8 agonist 4 能够有效的抑制野生型和耐药（拉米夫定和恩替卡韦）HBV 菌株，他们的IC50值分别为 0.15 和 0.10 μM。