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Search Results for " l-homoserine "

33

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37746	N-phenylacetyl-L-Homoserine lactone	Others	Others
	N-phenylacetyl-L-Homoserine lactone 可衰减病原体鲍曼不动杆菌的群体感应，可用于研究细菌感染。
T37739	N-decanoyl-L-Homoserine lactone C10-HSL,N-decanoyl-L-Homoserine lactone	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高，增加丝裂原激活蛋白激酶 6 (MPK6) 的活性，并促使一氧化氮 (NO) 的产生。
T22374	N-(beta-Ketocaproyl)-L-hoMoserine lactone N-3-氧-己酰高丝氨酸内酯,N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone	Others	Others
	N-(beta-Ketocaproyl)-L-hoMoserine lactone (N-(Ketocaproyl)-L-homoserine lactone) 是群体调节感应的成分之一。
T37744	N-octanoyl-L-Homoserine lactone C8-HSL,N-octanoyl-L-Homoserine lactone,OHL	Antibacterial	Microbiology/Virology
	N-octanoyl-L-Homoserine lactone (C8-HSL) 是一种具有扩散性的外源性鼠疫耶尔森菌群体感应分子，可调节LcrV毒力因子，通过参与群体感应控制基因表达，影响细胞代谢。N-octanoyl-L-Homoserine lactone 是用于研究囊性纤维的感染。
T18408	N-Butanoyl-L-homoserine lactone N-丁酰基-L-高丝氨酸内酯,N-Butyryl-L-homoserine lactone,C4-HSL	Antibacterial	Microbiology/Virology
	N-Butanoyl-L-homoserine lactone (C4-HSL) 是一种可降解的 ADClinker，用于抗体偶联药物的合成。它可用于抗菌生物膜，具有抗菌活性。它的适配体抑制铜绿假单胞菌生物膜的形成，可用于阻止群体感应。
T22375	N-hexanoyl-L-Homoserine lactone 己酰-L-高丝氨酸内酯,C6-HSL	Others; Antibacterial	Microbiology/Virology; Others
	N-hexanoyl-L-Homoserine lactone (C6-HSL) 是一种可扩散信号分子，参与控制基因表达、影响细胞代谢和群体感应。
T13789	N-dodecanoyl-L-Homoserine lactone C12-HSL,十二烷酰-L-高丝氨酸内酯	Others	Others
	N-dodecanoyl-L-Homoserine lactone (C12-HSL) 是群体感应 (QS) 信号分子的一种。它适配体可用于阻止群体感应，并能够阻碍铜绿假单胞菌 (Pseudomonas aeruginosa) 生物膜的形成。
T41287	N-3-Oxo-octanoyl-L-homoserine lactone	Others	Others
	N-3-Oxo-octanoyl-L-homoserine lactone 是一种群体感应信号分子，是农杆菌自诱导剂。
T33828	O-Succinylhomoserine O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine	Others	Others
	O-Succinylhomoserine (O-Succinyl-L-homoserine) 是大肠杆菌合成胱硫醚的中间体。
T38313	L-Homoserine lactone (hydrochloride)
	L-Homoserine lactone is a synthetic intermediate.1,2It has been used in the synthesis of organoselenium chemistry intermediates and analogs of bacterial quorum-sensing signaling molecules. 1.Koch, T., and Buchardt, O.Synthesis of L-(+)-selenomethionineSynthesis1065-1067(1993) 2.Chhabra, S.R., Harty, C., Hooi, D.S.W., et al.Synthetic analogues of the bacterial signal (quorum seensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulatorsJ. Med. Chem.46(1)97-104(2003)
T16226	N-(Ketocaproyl)-DL-homoserine lactone N-(Ketocaproyl)-D,L-homoserine lactone,N-(3-氧代己酰)-DL-高丝氨酸内酯	Antibacterial	Microbiology/Virology
	N-(Ketocaproyl)-DL-homoserine lactone 是群体感应自动诱导剂。它是 LuxR 的天然配体。
T37745	N-pentadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T41282	N-Heptanoyl-L-homoserine lactone

T38300	Acetyl-L-Homoserine lactone
	Acetyl-L-homoserine lactone belongs to the family of N-acylated homoserine lactones (HSLs) and has an acyl chain length of two carbons. HSLs perform a role in quorum sensing; however, unlike other HSLs, acetyl-L-homoserine lactone does not elicit a response in bacteria. In an assay of carbapenem antibiotic biosynthesis, acetyl-L-homoserine lactone does not induce a response in E. carotovora. In a fluorescence assay using E. coli containing a reporter plasmid of GFP expression in response to exog...
T37741	N-hexadecanoyl-L-Homoserine lactone C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...
T37878	N-tridecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37879	N-undecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37747	N-tetradecanoyl-L-Homoserine lactone C14-HSL,tDHL,N-tetradecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-tetradecanoyl-L-Homoserine lactone (C14-HSL) is a small diffu...
T37743	N-octadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T37335	N-3-hydroxybutyryl-L-Homoserine lactone
	N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.3 \|1. Purohit, A.A., Johansen, J.A., Hansen, H., et al. Presence of acyl-homoserine lactones in 57 members of the Vibrionaceae family. J. Appl. Microbiol. 115(3), 835-847 (2013).\|2. Feng, Z., Sun,...
T38154	N-3-hydroxydecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression. N-3-hydroxydecanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, al...
T37339	N-3-oxo-tetradecanoyl-L-Homoserine lactone 3-oxo-C14-HSL,N-3-oxo-myristoyl-L-Homoserine lactone,N-3-oxo-tetradecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-3-oxo-tetradecanoyl-L-homoserine lactone (3-oxo-C14-HSL) is ...
T37738	N-cis-tetradec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene...
T21633	N-3-oxo-dodecanoyl-L-Homoserine lactone
	N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) 是由铜绿假单胞菌和洋葱状芽孢杆菌复合物菌株产生的细菌群体感应信号分子，群体感应是细菌用来控制基因表达以响应细胞密度增加的调节系统。N-3-oxo-dodecanoyl-L-Homoserine lactone 诱导 16HBE 人支气管上皮细胞产生 IL-8。
T37337	N-3-oxo-hexadecanoyl-L-Homoserine lactone
	N-3-oxo-hexadecanoyl-L-Homoserine lactone is an unusual, substituted, long-chain N-acyl-homoserine lactone (AHL) produced by some bacteria, including strains of Agrobacterium vitis and Pseudomonas. Like other AHLs, this C16-containing form is thought to be involved in quorum sensing. Substituted, long-chain AHLs, including N-3-oxo-tetradecanoyl-L-homoserine lactone , prime for systemic acquired resistance to pathogen attack in plants.
T37338	N-3-oxo-pentanoyl-L-Homoserine lactone
	N-3-oxo-pentanoyl-L-Homoserine lactone is a chain-shortened derivative of the bacterial quorum sensing signaling molecule N-3-oxo-octanoyl-L-homoserine lactone .1It inhibits binding of the autoinducer N-3-oxo-hexanoyl homoserine lactone toE. colicontaining the transcription factor LuxR when used at a concentration of 230 nM.2It acts as an autoinducer to activate theV. fischeriluminescence system inE. coliwhen used at concentrations ranging from 20 to 200 nM. 1.Chhabra, S.R., Stead, P., Bainton, ...
T37737	N-cis-octadec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gene...
T37736	N-cis-hexadec-9Z-enoyl-L-Homoserine lactone N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of whic...
T36988	N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone
	N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone is a long-chain N-acyl-homoserine lactone (AHL) produced by some Gram-negative bacteria and is involved in quorum sensing. Quorum sensing enables bacteria to change gene expression based on cues from nearby bacteria and from eukaryotic hosts about nutrients, environmental conditions, or threats. Due to the benefit of quorum sensing for bacterial survival, quorum sensing molecules are potential targets for controlling bacterial infections. In...
T37336	N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T67363	Boc-L-Homoserine
	Boc-L-Homoserine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67363，CAS号为 41088-86-2。
T36396	D-Homoserine lactone
	D-homoserine lactone is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki= 11 mM for the rabbit enzyme).1 1.Wang, E.A., Kallen, R., and Walsh, C.Mechanism-based inactivation of serine transhydroxymethylases by D-fluoroalanine and related amino acidsJ. Biol. Chem.256(13)6917-6926(1981)
T37342	N-butyryl-L-Homocysteine thiolactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-...

化合物

N-phenylacetyl-L-Homoserine lactone

Cat.No: T37746

Target: Others

N-decanoyl-L-Homoserine lactone

Cat.No: T37739

Synonym: C10-HSL,N-decanoyl-L-Homoserine lactone

Target: Reactive Oxygen Species, Antibacterial

N-(beta-Ketocaproyl)-L-hoMoserine lactone

Cat.No: T22374

Synonym: N-3-氧-己酰高丝氨酸内酯,N-(β-Ketocaproyl)-L-hoMoserine lactone,N-(Ketocaproyl)-L-homoserine lactone,N-(β-Ketocaproyl)-L-hoMoserine lactone

Target: Others

N-octanoyl-L-Homoserine lactone

Cat.No: T37744

Synonym: C8-HSL,N-octanoyl-L-Homoserine lactone,OHL

Target: Antibacterial

N-Butanoyl-L-homoserine lactone

Cat.No: T18408

Synonym: N-丁酰基-L-高丝氨酸内酯,N-Butyryl-L-homoserine lactone,C4-HSL

Target: Antibacterial

N-hexanoyl-L-Homoserine lactone

Cat.No: T22375

Synonym: 己酰-L-高丝氨酸内酯,C6-HSL

Target: Others, Antibacterial

N-dodecanoyl-L-Homoserine lactone

Cat.No: T13789

Synonym: C12-HSL,十二烷酰-L-高丝氨酸内酯

Target: Others

N-3-Oxo-octanoyl-L-homoserine lactone

Cat.No: T41287

Target: Others

O-Succinylhomoserine

Cat.No: T33828

Synonym: O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine

Target: Others

L-Homoserine lactone (hydrochloride)

Cat.No: T38313

N-(Ketocaproyl)-DL-homoserine lactone

Cat.No: T16226

Synonym: N-(Ketocaproyl)-D,L-homoserine lactone,N-(3-氧代己酰)-DL-高丝氨酸内酯

Target: Antibacterial

N-pentadecanoyl-L-Homoserine lactone

Cat.No: T37745

N-Heptanoyl-L-homoserine lactone

Cat.No: T41282

Acetyl-L-Homoserine lactone

Cat.No: T38300

N-hexadecanoyl-L-Homoserine lactone

Cat.No: T37741

Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

N-tridecanoyl-L-Homoserine lactone

Cat.No: T37878

N-undecanoyl-L-Homoserine lactone

Cat.No: T37879

N-tetradecanoyl-L-Homoserine lactone

Cat.No: T37747

Synonym: C14-HSL,tDHL,N-tetradecanoyl-L-Homoserine lactone

N-octadecanoyl-L-Homoserine lactone

Cat.No: T37743

N-3-hydroxybutyryl-L-Homoserine lactone

Cat.No: T37335

N-3-hydroxydecanoyl-L-Homoserine lactone

Cat.No: T38154

N-3-oxo-tetradecanoyl-L-Homoserine lactone

Cat.No: T37339

Synonym: 3-oxo-C14-HSL,N-3-oxo-myristoyl-L-Homoserine lactone,N-3-oxo-tetradecanoyl-L-Homoserine lactone

N-cis-tetradec-9Z-enoyl-L-Homoserine lactone

Cat.No: T37738

N-3-oxo-dodecanoyl-L-Homoserine lactone

Cat.No: T21633

N-3-oxo-hexadecanoyl-L-Homoserine lactone

Cat.No: T37337

N-3-oxo-pentanoyl-L-Homoserine lactone

Cat.No: T37338

N-cis-octadec-9Z-enoyl-L-Homoserine lactone

Cat.No: T37737

N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

Cat.No: T37736

Synonym: N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

N-(3-hydroxy-7-cis tetradecenoyl)-L-Homoserine lactone

Cat.No: T36988

N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone

Cat.No: T37336

Boc-L-Homoserine

Cat.No: T67363

D-Homoserine lactone

Cat.No: T36396

N-butyryl-L-Homocysteine thiolactone

Cat.No: T37342

Cat. No.	Product Name	Target	Signaling Pathways
T4757	L-Homoserine (S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID	Others; Endogenous Metabolite	Metabolism; Others
	L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) 是天然存在的非蛋白丝氨酸，是合成苏氨酸、蛋氨酸和赖氨酸的共有中间体。它是氨基酸丝氨酸的更具反应性的变体。
T81722	N-(3-Oxodecanoyl)-L-homoserine lactone 3-Oxo-C10-HSL
	N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) 作为一种信号分子，在细菌群体感应中充当自诱导分子的角色。
T75448	Aculene D
	Aculene D, 一种真菌代谢物，针对Chromobacterium violaceum CV026表现出群体感应(QS)抑制活性。该化合物能在亚抑制浓度下，显著削减由N-己酰基-l-高丝氨酸内酯(C6-HSL)触发的C. violaceum CV026培养物中紫罗兰素的产生。

天然产物

Cat.No: T4757

Synonym: (S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID

Target: Others, Endogenous Metabolite

N-(3-Oxodecanoyl)-L-homoserine lactone

Cat.No: T81722

Synonym: 3-Oxo-C10-HSL

Cat.No: T75448

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