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16

抑制剂 & 化合物

9

天然产物

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Cat. No. Product Name Target Signaling Pathways
T35606 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium

1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) 可与 DOPC 和 DOPE 一起用于脂质混合物中,作为有效的无毒和非病毒 DNA 载体。 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium 已用于单层囊泡的形成,以研究曲率对膜结构的影响,并用于支持脂质双层的形成,以研究各种支持膜小叶之间脂质重新分布的材料。
T36065 N-Oleoyl-L-Serine

Bone mass and shape is continuously remodeled by the concerted and balanced action of osteoblasts (bone forming cells) and osteoclasts (bone-resorbing cells). The endocannabinoid system plays an essential role in the maintenance of normal bone mass via signaling through the CB2 receptor. N-Oleoyl-L-serine is an endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption.
T32902 L-Serine-1-13C

L-(1-13C)Serine,L-(l-13C)Serine

L-Serine-1-13C is an amino acid.
T8350 TPCK

Proteasome Proteases/Proteasome; Ubiquitination
TPCK 是丝氨酸蛋白酶抑制剂,通过与 HPV-18 E7 蛋白的视网膜母细胞瘤蛋白 (RB) 结合核心发生反应,并能够消除其 RB 结合能力。将它添加到培养基内,可修饰活角质形成细胞中的 E7 蛋白。
T66681 Glycyl-l-serine

Glycyl-l-serine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66681,CAS号为 7361-43-5。
T78617 N-Acetylserine

N-Acetyl-L-serine

Endogenous Metabolite Metabolism
N-Acetylserine(N-Acetyl-L-serine)可与CysB脱辅基蛋白结合,作为半胱氨酸生物合成中的生理诱导剂。此外,该化合物能够刺激cysJIH基因在体外(in vitro)的转录。
T25495 Hexadecylphosphoserine

Hexadecylphospho-L-serine,Hexadecyl phosphoserine,Hexadecyl-phosphoserine

Hexadecylphosphoserine is a representative growth inhibitor.
T71898 Bromotubercidin

Bromotubercidin is a reversible inhibitor of RNA synthesis. Bromotubercidin is a biochemical.
T63847 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium

Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) 是一种改性 PS 产品,经由 NADPH 氧化酶激活及 Lyso-PS 信号转导后得到。Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium 能够利用巨噬细胞 G2A 功能,增强现有的受体/配体系统,进而解决中性粒细胞炎症。
T24311 L 658758

L 658,758,L-658758,L-658,758,L658,758,L658758

L 658758 is an inhibitor of serine proteinase.
T34618 Serratamic acid

Serratamic acid is an L-serine derivative produced by organisms of the Serratia group.
T68417 SAT-IN-3

SAT-IN-3 is a novel inhibitor of salmonella serine acetyltransferase (SAT), the enzyme that catalyzes the rate-limiting step of L-cysteine biosynthesis.
T36396 D-Homoserine lactone

D-homoserine lactone is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki= 11 mM for the rabbit enzyme).1 1.Wang, E.A., Kallen, R., and Walsh, C.Mechanism-based inactivation of serine transhydroxymethylases by D-fluoroalanine and related amino acidsJ. Biol. Chem.256(13)6917-6926(1981)
T10939 D,L-Cystathionine dihydrochloride

Others Others
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.
T38214 1-Deoxysphingosine (m18:1(4E))

1-Deoxysphingosine (m18:1(4E))

1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 Plasma levels of 1-deoxysphingosine (m18:1(4E)) are increased in patients with chronic idiopathic axonal neuropathy (CIAP) and diabetic distal symmetrical polyneuropathy (DSPN).3 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemica...
T62494 Cathepsin C-IN-5

CathepsinC-IN-5 (compound SF38) 为一高效、选择性、口服活性的组织蛋白酶 C (Cat C) 抑制剂,其针对Cat C、Cat L、Cat S、Cat B、Cat K 的IC50s 分别为 59.9 nM、4.26 µM、>5 µM、>5 µM、>5 µM。该化合物能够抑制骨髓和血液中的Cat C活性,降低中性粒细胞丝氨酸蛋白酶(NSP)的激活,并展现抗炎活性。

化合物

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
Cat.No: T35606
Synonym: 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)
Target:
N-Oleoyl-L-Serine
Cat.No: T36065
Synonym:
Target:
L-Serine-1-13C
Cat.No: T32902
Synonym: L-(1-13C)Serine,L-(l-13C)Serine
Target:
TPCK
Cat.No: T8350
Synonym:
Target: Proteasome
Glycyl-l-serine
Cat.No: T66681
Synonym:
Target:
N-Acetylserine
Cat.No: T78617
Synonym: N-Acetyl-L-serine
Target: Endogenous Metabolite
Hexadecylphosphoserine
Cat.No: T25495
Synonym: Hexadecylphospho-L-serine,Hexadecyl phosphoserine,Hexadecyl-phosphoserine
Target:
Bromotubercidin
Cat.No: T71898
Synonym:
Target:
1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
Cat.No: T63847
Synonym:
Target:
L 658758
Cat.No: T24311
Synonym: L 658,758,L-658758,L-658,758,L658,758,L658758
Target:
Serratamic acid
Cat.No: T34618
Synonym:
Target:
SAT-IN-3
Cat.No: T68417
Synonym:
Target:
D-Homoserine lactone
Cat.No: T36396
Synonym:
Target:
D,L-Cystathionine dihydrochloride
Cat.No: T10939
Synonym:
Target: Others
1-Deoxysphingosine (m18:1(4E))
Cat.No: T38214
Synonym: 1-Deoxysphingosine (m18:1(4E))
Target:
Cathepsin C-IN-5
Cat.No: T62494
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2O2730 L-Serine

(S)-Serine,L-丝氨酸,丝氨酸,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid

Endogenous Metabolite Metabolism
L-Serine (serine) 是一种人体非必需氨基酸,它存在于许多蛋白质中,并且在功能上很重要。L-Serine 也存在于丝氨酸蛋白酶类的活性位点,包括胰蛋白酶和凝乳胰蛋白酶。
T1324 O-Phospho-L-serine

L-Serine O-phosphate,磷酸化丝氨酸,Phosphoserine,Dexfosfoserine,L-SOP

Amino Acids and Derivatives; Endogenous Metabolite; GluR; NMDAR Metabolism; Neuroscience
O-Phospho-L-serine (Phosphoserine) 是 L-serine 合成过程中的直接前体物质,是 mGluR 激动剂。
T4722 O-Acetyl-L-serine hydrochloride

Others; Endogenous Metabolite Metabolism; Others
O-Acetyl-L-serine hydrochloride 是内源性代谢产物的一种。
TQ0158 Azaserine

CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine

Others; Antibiotic Microbiology/Virology; Others
Azaserine (CI-337) 是一种从链霉菌属中分离出来的肿瘤抑制抗生素,可作为谷氨酰胺氨基转移酶的抑制剂。
T5057 DL-O-Phosphoserine

DL-O-磷酸丝氨酸,DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP

Others; Endogenous Metabolite Metabolism; Others
DL-O-Phosphoserine (DL-SOP) 是丝氨酸和磷酸的酯,是人类生物流体中的正常代谢物。
T8095 O-Acetylserine

O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸

Others; Endogenous Metabolite Metabolism; Others
O-Acetylserine (O-Acetyl-L-serine) 是细菌和植物中半胱氨酸合成过程中的中间体。
T8363 DL-Serine

PKM Metabolism
DL-Serine 是 D-丝氨酸和 L-丝氨酸的混合物,是一种基础代谢物。它具有抗病毒作用,能抑制烟草花叶病毒的增殖。
T4757 L-Homoserine

(S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID

Others; Endogenous Metabolite Metabolism; Others
L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) 是天然存在的非蛋白丝氨酸,是合成苏氨酸、蛋氨酸和赖氨酸的共有中间体。它是氨基酸丝氨酸的更具反应性的变体。
T4839 Ac-Ala-OH

N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸

Others; Endogenous Metabolite Metabolism; Others
Ac-Ala-OH (N-Acetyl-L-alanine) 是鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O) γ -2亚基、髓鞘碱性蛋白、GTP-结合核蛋白 Ran、原肌球蛋白 α - 4链、HIV-1 Rev 结合蛋白2、Xaa-Pro 二肽酶、胸腺酶 β -10、肌动蛋白样蛋白3、丙氨酸转氨酶、丝氨酸/苏氨酸蛋白磷酸酶PP1 - β催化亚基、10 kda 热休克蛋白(线粒体)、钙调蛋白和 β -1-syntrophin 的底物。

天然产物

L-Serine
Cat.No: T2O2730
Synonym: (S)-Serine,L-丝氨酸,丝氨酸,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid
Target: Endogenous Metabolite
O-Phospho-L-serine
Cat.No: T1324
Synonym: L-Serine O-phosphate,磷酸化丝氨酸,Phosphoserine,Dexfosfoserine,L-SOP
Target: Amino Acids and Derivatives, Endogenous Metabolite, GluR, NMDAR
O-Acetyl-L-serine hydrochloride
Cat.No: T4722
Synonym:
Target: Others, Endogenous Metabolite
Azaserine
Cat.No: TQ0158
Synonym: CI-337,偶氮丝胺酸,P-165,氮杂丝氨酸,O-Diazoacetyl-L-serine
Target: Others, Antibiotic
DL-O-Phosphoserine
Cat.No: T5057
Synonym: DL-O-磷酸丝氨酸,DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP
Target: Others, Endogenous Metabolite
O-Acetylserine
Cat.No: T8095
Synonym: O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸
Target: Others, Endogenous Metabolite
DL-Serine
Cat.No: T8363
Synonym:
Target: PKM
L-Homoserine
Cat.No: T4757
Synonym: (S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID
Target: Others, Endogenous Metabolite
Ac-Ala-OH
Cat.No: T4839
Synonym: N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸
Target: Others, Endogenous Metabolite
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