Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24239 |
K201
K-201,JTV 519,JTV-519,K 201 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
K201 (JTV-519) 是一种 Ca2+ 依赖性阻滞剂,通过稳定兰尼碱受体来防止缺血性心脏和骨骼肌 (SkM) 中的肌质网异常 Ca(2+) 泄漏。 | |||
T11732 |
JTV-519 hemifumarate
K201 hemifumarate |
MELK | PI3K/Akt/mTOR signaling |
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. | |||
T11731 |
JTV-519 free base
K201 free base |
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle. | |||
T75883 |
Agitoxin-2 TFA
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Agitoxin-2 TFA 是K+通道的阻断剂,其对 mKV1.3 和 mKV1.1 的IC50值分别为 201 pM 和 144 pM。 |