搜索结果

Search Results for " influenza a virus-in-8 "

抑制剂 & 化合物

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T74762	Influenza A virus-IN-8
	Influenza A virus-IN-8 (S5) 为一种大环肽，无细胞毒性，并作为甲型流感病毒 (IAV) 的有效抑制剂，显示出较好的蛋白酶稳定性。其对 H1 和 H5 变体的IC50值分别低至 6.7 nM 和 6.6 nM。此外，Influenza A virus-IN-8 能够与 HA 茎的一个保守区域结合，特别是对 H1 变体展现出 1.0 nM 的高亲和性Kd 值。
TP1822L	CEF6 acetate(913545-15-0 free base)	Influenza Virus	Microbiology/Virology
	CEF6 acetate(913545-15-0 free base) 是 HLA-B7限制性流感病毒核蛋白表位，属于 CEF 对照肽。 CEF 对照肽长度为 8-12 个氨基酸，其序列来自人类巨细胞病毒、爱泼斯坦-巴尔病毒和流感病毒。
T26873	BMY-27709 BMY 27709,BMY27709	Influenza Virus	Microbiology/Virology
	BMY-27709 是一种流感病毒生长抑制剂，对 A/WSN/33 病毒生长的 IC50 值为 3-8 μM，对流感病毒的部分亚型也展现出抑制活性。BMY-27709 对 H1 和 H2 病毒感染的早期起作用，通过抑制血凝素蛋白展现其抗病毒活性。然而，BMY-27709 对 H3 亚型病毒以及 B 型/Lee/40 流感病毒没有作用。
TP1822	CEF6
	CEF6, a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenza virus.
T10677	Carbodine	Others	Others
	Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent and targets CTP synthetase that converts UTP to CTP. It possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro.
T38340	10-Norparvulenone
	10-Norparvulenone is a fungal metabolite originally isolated fromMicrosphaeropsis.1It decreases viral sialidase activity in, and increases survival of, MDCK cells infected with the mouse-adapted influenza virus A/PR/8/34 when used at a concentration of 1 μg/ml. 1.Fukami, A., Nakamura, T., Kim, Y.P., et al.A new anti-influenza virus antibiotic, 10-norparvulenone from Microsphaeropsis sp. FO-5050J. Antibiot. (Tokyo)53(10)1215-1218(2000)
T27983	MBX2546 MBX-2546,MBX 2546
	MBX2546 is an Influenza A Virus Fusion Inhibitor. MBX2546 binds to HA and inhibits HA-mediated membrane fusion. Both binding and stabilization of HA by MBX2546 are required for the inhibition of viral infection. Mutations in MBX2546-resistant influenza A/
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...
T62812	RdRP-IN-4
	RdRP-IN-4 (compound 11q) 是一种芳基苯甲酰肼类似物，是一种口服具有活力的甲型流感病毒 RNA 依赖性 RNA 聚合酶 (RdRp) 抑制剂，能够直接结合 RdRp 的 PB1 亚基。RdRP-IN-4 可有效抑制 H5N1 禽流感病毒株，在 MDCK 细胞的 EC50=18 nM。RdRP-IN-4 对 H1N1 (A/PR/8/34) Flu A 株和 Flu B 株 (B/Lee/1940) 具有抑制作用，其 EC50 值分别为 53 nM 和 20 nM。RdRP-IN-4 以剂量依赖性方式显著抑制病毒核蛋白 (NP) 的表达水平。RdRP-IN-4 在受感染的小鼠中具有明显的抗病毒作用。

化合物

Influenza A virus-IN-8

Cat.No: T74762

Synonym:

Target:

CEF6 acetate(913545-15-0 free base)

Cat.No: TP1822L

Synonym:

Target: Influenza Virus

BMY-27709

Cat.No: T26873

Synonym: BMY 27709,BMY27709

Target: Influenza Virus

Synonym: MBX-2546,MBX 2546

Cat. No.	Product Name	Target	Signaling Pathways
TN1347	8-Prenylkaempferol 去甲脱水淫羊藿黄素	p38 MAPK; NF-κB; PI3K	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and

天然产物

8-Prenylkaempferol

Cat.No: TN1347

Synonym: 去甲脱水淫羊藿黄素

Target: p38 MAPK, NF-κB, PI3K

* 搜索：		* 机关/企业：
* 邮箱：		* 电话：
备注：
验证码：

搜索结果

抑制剂 & 化合物

天然产物

提交您的定制咨询

化合物

天然产物