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抑制剂 & 化合物

1

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Cat. No.	Product Name	Target	Signaling Pathways
T7339	Angiotensin (1-7) Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO	RAAS; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性，因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮，是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大，并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。
T32214	Isoleucylvaline Ile-val
	Isoleucylvaline is a dipeptide.
T32678	Leucyl-valyl-isoleucinamide Leu-val-ile-NH2,Leu-val-ile-amide
	Leucyl-valyl-isoleucinamide is a oligopeptide.
TP2375	C112 Peptide Ile-arg-pro-val-gln
	C112 Peptide is a novel peptide.
TP2409	SP-346 nonapeptide H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2
	SP-346 nonapeptide is a pipecolic acid substituted nonapeptide.
TP2371	Asudemotide Glu-tyr-tyr-glu-leu-phe-val-asn-ile
	Asudemotide is a bioactive chemical.
T81354	PTD2 Ac-Gly-Val-Nle-Arg-Ile-NH2
	PTD2（Ac-Gly-Val-Nle-Arg-Ile-NH2）是一种针对WHSC1具有高选择性的抑制剂，展现出对WHSC1的亚微摩尔级亲和力。
T32408	KNI 122 Ser-Phe-Asn-Pns-Pro-Ile-Val-NH2,KNI-122,KNI122
	KNI 122is a heptapeptide analog.
T76583	H-Ile-Lys-Val-Ala-Val-OH
	H-Ile-Lys-Val-Ala-Val-OH 是层纤蛋白-1 有效的活性位点之一。H-Ile-Lys-Val-Ala-Val-OH 可促进细胞粘附、神经突生长和肿瘤生长。H-Ile-Lys-Val-Ala-Val-OH 通过激活 MAPK/ERK1/2和 PI3K/Akt 信号通路，刺激 BMMSC 细胞生长和增殖。
T21582L	Acetyl Angiotensinogen (1-14), porcine Acetate Acetyl Angiotensinogen (1-14), porcine Acetate（66641-26-7 Free base）	Others	Others
	Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽，序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。
TP1528	Angiotensin I/II (1-5) Angiotensin I/II 1-5	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-5) 是由血管紧张素 I/II 肽转化而来，有 1-5 个氨基酸组成的多肽。血管紧张素 I 是由肾素对血管紧张素原的作用形成的，血管紧张素 I 可产生血管紧张素 II 。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
TP1579	Angiotensin I/II (1-6) Angiotensin I/II 1-6	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来，含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解，形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
T82142	Hymenistatin I
	Hymenistatin I，一种环八肽[c-(-Pro-Pro-Tyr-Val-Pro-Leu-Ile-ile-Ile-)]，具有免疫抑制活性，影响体液和细胞免疫应答。
TP2256	heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]	Others	Others
	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.
TP2287	Rac GTPase fragment	Others	Others
	Rac GTPase fragment is a peptide with the sequence H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH, MW= 1019.15. Rac is a subfamily of the Rho family of GTPases, small signaling G proteins (more specifically a GTPase).
T23555	Z-VEID-FMK	Others	Others
	When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluorometh
TP2269	MAP kinase fragment [Multiple species]	Others	Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group.
TP2257	Histone-H2A-(107-122)-Ac-OH	Others	Others
	Histone-H2A-(107-122)-Ac-OH is a peptide with the sequence Ac-Gly-Val-Leu-Pro-Asn-Ile-Gln-Ala-Val-Leu-Leu-Pro-Lys-Lys-Thr-Glu-OH, MW= 1762.1. Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
TP2220	Angiotensin 1/2 (1-8) amide	Others	Others
	Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is us
TP2182	Lamin fragment	Others	Others
	Lamin fragment has a peptide sequence of Lys-Ala-Gly-Gln-Val-Val-Thr-Ile-Trp. Lamin polypeptides have an almost complete α-helical conformation with multiple α-helical domains separated by non-α-helical linkers that are highly conserved in length and amin

化合物

Angiotensin (1-7)

Cat.No: T7339

Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

Target: RAAS, Endogenous Metabolite

Isoleucylvaline

Cat.No: T32214

Synonym: Ile-val

Leucyl-valyl-isoleucinamide

Cat.No: T32678

Synonym: Leu-val-ile-NH2,Leu-val-ile-amide

Cat.No: TP2375

Synonym: Ile-arg-pro-val-gln

SP-346 nonapeptide

Cat.No: TP2409

Synonym: H-Val-Ser-Gln-Asn-Tyr-Pip-Ile-Val-Gln-NH2

Cat.No: TP2371

Synonym: Glu-tyr-tyr-glu-leu-phe-val-asn-ile

Cat.No: T81354

Synonym: Ac-Gly-Val-Nle-Arg-Ile-NH2

Cat.No: T32408

Synonym: Ser-Phe-Asn-Pns-Pro-Ile-Val-NH2,KNI-122,KNI122

H-Ile-Lys-Val-Ala-Val-OH

Cat.No: T76583

Acetyl Angiotensinogen (1-14), porcine Acetate

Cat.No: T21582L

Synonym: Acetyl Angiotensinogen (1-14), porcine Acetate（66641-26-7 Free base）

Target: Others

Angiotensin I/II (1-5)

Cat.No: TP1528

Synonym: Angiotensin I/II 1-5

Target: RAAS, Others

Angiotensin I/II (1-6)

Cat.No: TP1579

Synonym: Angiotensin I/II 1-6

Target: RAAS, Others

Cat.No: T82142

heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

Cat.No: TP2256

Target: Others

Rac GTPase fragment

Cat.No: TP2287

Target: Others

Cat.No: T23555

Target: Others

MAP kinase fragment [Multiple species]

Cat.No: TP2269

Target: Others

Histone-H2A-(107-122)-Ac-OH

Cat.No: TP2257

Target: Others

Angiotensin 1/2 (1-8) amide

Cat.No: TP2220

Target: Others

Cat.No: TP2182

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6446	Cyclo(Ile-Val)
	Cyclo(Ile-Val) shows moderate antifungal and weak antitumor activities in vitro.

天然产物

Cyclo(Ile-Val)

Cat.No: TN6446

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