Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82056 |
IP2
|
||
IP2作为免疫调节剂,能增强癌细胞内PTP衍生的抗原呈递,但对癌细胞本身不具有细胞毒性。在小鼠实验中,IP2能诱导肿瘤生长缺陷。 | |||
T12901 |
SHIP2-IN-1
|
Phosphatase | Metabolism |
SHIP2-IN-1 是一种 SHIP2 抑制剂,IC50=2 µM。它能够使 GSK3β 的 Ser9 位点磷酸化,抑制 GSK3β 的活化。它可用于研究阿尔滋海默症。 | |||
T12728 |
RIP2 Kinase Inhibitor 3
|
Others; RIP kinase | Apoptosis; NF-κB; Others |
RIP2 Kinase Inhibitor 3 是一种有效的选择性 受体相互作用蛋白2 激酶抑制剂,IC50 为 1 nM。 | |||
T16753 | RIP2 kinase inhibitor 2 | Others | Others |
RIP2 kinase inhibitor 2 is a receptor-interacting protein-2 kinase inhibitor. | |||
T39574 |
RIP2 Kinase Inhibitor 4
|
||
RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (with a pIC50 value of 8) and effectively inhibits the release of TNF-α. | |||
T12727 |
RIP2 kinase inhibitor 1
|
Others | Others |
RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 μM ),and is used for autoinflammatory disorders. |