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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22450 |
Tyrphostin B44, (+) enantiomer
酪氨酸磷酸化抑制剂AG 835 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Tyrphostin B44, (+) enantiomer 是一种表皮生长因子受体 (EGFR) 激酶抑制剂,IC50 为 0.86 μM,活性低于 (-) 对映体。 | |||
T6721 |
Vinblastine
|
Microtubule Associated; AChR | Cytoskeletal Signaling; Neuroscience |
Vinblastine 抑制微管形成并抑制 nAChR 活性,IC50 为 8.9 μM,用于治疗某些类型的癌症。 | |||
T29434 |
4-Desacetylvinblastine hydrazide
DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide |
||
Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent. | |||
T18330 |
MC-Val-Cit-PAB-vinblastine
|
Others | Others |
MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1668 |
Vinblastine sulfate
硫酸长春碱,NSC49842,Vincaleukoblastine sulfate salt |
Microtubule Associated; AChR; Autophagy | Autophagy; Cytoskeletal Signaling; Neuroscience |
Vinblastine sulfate (Vincaleukoblastine sulfate salt) 是对各种癌症类型有细胞毒性的生物碱。 它可以抑制微管的形成,也可以抑制 nAChR,IC50值为8.9 μM。 | |||
T3022 |
Anhydrovinblastine
脱水长春碱,3',4'-Anhydrovinblastine |
Others | Others |
3',4'-Anhydrovinblastine (3',4'-Anhydrovinblastine) 是一种提取自Catharanthus roseus 叶片的单萜吲哚生物碱。 |