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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T15572 IN-1130

ALK Angiogenesis; Tyrosine Kinase/Adaptors
IN-1130 是一种选择性的 ALK5 抑制剂,对 ALK5 介导的 Smad3 磷酸化、酪蛋白和 p38α 丝裂原活化蛋白激酶的 ALK5 磷酸化,IC50 值为 5.3 nM、36 nM 和 4.3 μM。
T11765 KPLH1130

Dehydrogenase; PDK Metabolism; PI3K/Akt/mTOR signaling
KPLH1130,一种选择性丙酮酸脱氢酶激酶(PDK)抑制剂,在高脂饮食(HFD)喂养的小鼠中提高了糖耐量。KPLH1130 抑制巨噬细胞极化并减轻了炎症反应。
TP1130 β-CGRP, human

CGRP-II (Human),Human β-CGRP

β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal

化合物

IN-1130
Cat.No: T15572
Synonym:
Target: ALK
KPLH1130
Cat.No: T11765
Synonym:
Target: Dehydrogenase, PDK
β-CGRP, human
Cat.No: TP1130
Synonym: CGRP-II (Human),Human β-CGRP
Target:
Cat. No. Product Name Target Signaling Pathways
TMA1130 2,4-Dihydroxyphenylacetic acid

Others Others
2,4-Dihydroxyphenylacetic acid is a functional moiety in the toxin molecule and the biological action of spider toxin is explained by direct interaction with an Fe-S center which is known to play an important role for the glutamate binding.

天然产物

2,4-Dihydroxyphenylacetic acid
Cat.No: TMA1130
Synonym:
Target: Others
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