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Cat. No.	Product Name	Target	Signaling Pathways
TP2047	CRF(6-33)(human) CRF (6-33)
	CRF(6-33)(human) is a Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
TP1144	Corticotropin-releasing factor (human) Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human
	Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions b
T75893	CRF(6-33)(human) TFA
	CRF(6-33)(human) TFA 是一种 CRF 结合蛋白配体 (CRF-BP) 抑制剂，与CRF-BP 竞争性结合，但不与突触后 CRF 受体结合。CRF(6-33)(human) TFA 具有抗肥胖作用。
T76602	(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
	(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 作为一种CRF拮抗剂，能有效阻断IL-1a诱发的黄体生成素 (LH) 抑制作用。
TP1199L	Urotensin I acetate (83930-33-0 Free base)	CRFR	GPCR/G Protein
	Urotensin I acetate 是一种 CRF 样神经肽，可作为 CRF 受体激动剂，对 CHO 细胞中的人 CRF1、人 CRF2 和大鼠 CRF2α 受体的 pEC50 分别为 11.46、9.36 和 9.85，对 CHO 细胞的 Kis 分别为 0.4、1.8 和 5.7 nM hCRF1、rCRF2α 和 mCRF2β 受体分别为。
T60126	4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine	Others; CRFR	GPCR/G Protein; Others
	4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine 是SSR-125543的对映异构体. SSR-125543是一种有效的CRF-R1拮抗剂，对人CRF-R1的Ki＝1.0nM。
T76180	Urocortin III (human)
	Urocortin III (human) 是一种促肾上腺皮质激素释放因子 (CRF) 相关肽。Urocortin III (human) 优先结合并激活CRF-R2，并且具有离散的中枢神经系统和外周分布。Urocortin III (human) 选择性结合 2 型 CRF 受体，mCRF2β、rCRF2α 和 hCRF1 的Ki 值分别为 13.5、21.7 和 >100 nM。Urocortin III (human) 介导Insulin(human) 分泌的生长抑素依赖性负反馈控制。
TP1190	CRF, bovine TFA (92307-52-3 free base) CRF, bovine TFA,Corticotropin Releasing Factor bovine TFA
	CRF, bovine (TFA) is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM[1]. CRF shows pEC50s of 11.16, 8.53 and 8
T26855	BMS-665053 BMS665053
	BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM). In addi
T37111	Corticotropin-releasing factor (human) (acetate)
	Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
TP1860	Urocortin II, human
	Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.
T75976	Urotensin I TFA
	Urotensin I (Catostomus urotensin I) TFA 是一种类 CRF 样肽，可作为 CRF 受体激动剂，在细胞实验中，对人 CRF1，CRF2和大鼠 CRF2α受体的 pEC50值分别为 11.46，9.36 和 9.85，对 hCRF1，rCRF2α和 mCRF2β受体的 Ki 值分别为 0.4，1.8 和 5.7 nM。
TP1021	Urocortin, human Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I	CRFR	GPCR/G Protein
	Urocortin, human (Human urocortin I) 是由 40 个氨基酸组成的神经多肽，是选择性 CRF2受体激动剂，作用于 hCRF1(Ki:0.4 nM)、rCRF2α(Ki:0.3 nM)、 mCRF2β(Ki:0.5 nM)。
T35814	Urocortin III (human) (trifluoroacetate salt)
	Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....
TP1557	Urocortin II, human TFA
	Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. Human urocortin II exhibits mild motor-suppressive effects and delayed anxiolytic-like effects，suggesting a time-depen
T75804	K41498 TFA
	K41498 TFA 是一种强选择性的CRF2 receptor 拮抗剂，其对人 CRF2α、CRF2β和 CRF1受体的Ki 值分别为 0.66 nM、0.62 nM 和425 nM。K41498 TFA 是 antisauvagine-30 (aSvg-30) 的类似物，可抑制 sauvagine 刺激的 cAMP 在 hCRF2α/hCRF2β表达细胞中的积累。K41498 可用于低血压研究。
TP1199	Urotensin I Catostomus urotensin I
	Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectivel
T76361	[DPro5] Corticotropin Releasing Factor, human, rat
	[DPro5] Corticotropin Releasing Factor, human, rat 是人类和大鼠促肾上腺皮质激素释放因子/激素 R2 的选择性激动剂。作为一种下丘脑激素，促肾上腺皮质激素释放因子 (CRF) 能够促进肾上腺皮质激素 (ACTH) 和 β-内啡肽的分泌。值得注意的是，[DPro5] Corticotropin Releasing Factor, human, rat 并不触发典型的焦虑反应，而是能调控大鼠的学习与记忆过程。

化合物

CRF(6-33)(human)

Cat.No: TP2047

Synonym: CRF (6-33)

Corticotropin-releasing factor (human)

Cat.No: TP1144

Synonym: Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human

CRF(6-33)(human) TFA

Cat.No: T75893

(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)

Cat.No: T76602

Urotensin I acetate (83930-33-0 Free base)

Cat.No: TP1199L

Target: CRFR

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine

Cat.No: T60126

Target: Others, CRFR

Urocortin III (human)

Cat.No: T76180

CRF, bovine TFA (92307-52-3 free base)

Cat.No: TP1190

Synonym: CRF, bovine TFA,Corticotropin Releasing Factor bovine TFA

Cat.No: T26855

Synonym: BMS665053

Corticotropin-releasing factor (human) (acetate)

Cat.No: T37111

Urocortin II, human

Cat.No: TP1860

Urotensin I TFA

Cat.No: T75976

Urocortin, human

Cat.No: TP1021

Synonym: Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I

Target: CRFR

Urocortin III (human) (trifluoroacetate salt)

Cat.No: T35814

Urocortin II, human TFA

Cat.No: TP1557

Cat.No: T75804

Cat.No: TP1199

Synonym: Catostomus urotensin I

[DPro5] Corticotropin Releasing Factor, human, rat

Cat.No: T76361

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