Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3293 |
Apoptozole
Apoptosis Activator VII |
Apoptosis; HSP | Apoptosis; Cytoskeletal Signaling; Metabolism |
Apoptozole (Apoptosis Activator VII) 是一种Hsc70和Hsp70的 ATPase 结构域抑制剂,可诱导凋亡,Kd 值分别为 0.21 和 0.14 μM。 | |||
T7010 |
VER-155008
VER155008 |
GPR; HSP; Autophagy | Autophagy; Cytoskeletal Signaling; Endocrinology/Hormones; GPCR/G Protein; Metabolism |
VER-155008 是一种Hsp70的抑制剂,对Hsp70、Hsc70 和 Grp7 的IC50值分别为 0.5 μM、2.6 μM 和 2.6 μM,对Hsp70的Kd 值为 0.3 μM,比 HSP90 选择性高 100 倍以上。 | |||
TP1616L |
Hsp70-derived octapeptide acetate
Hsp70-derived octapeptide acetate(736171-62-3 free base) |
Others | Others |
Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate)(736171-62-3 free base) 是一组含有四肽重复 (TPR) 的蛋白质,已显示与 70 kDa 热休克同源蛋白 (hsc70) 的 C 末端结构域相互作用。在本研究中,含 TPR 的蛋白质,包括 hsc70 相互作用蛋白 (CHIP)、TPR1 和人富含谷氨酰胺的 TPR 含蛋白 (hSGT) 的 C 端,对 DnaJ 和 hsc70 对荧光素酶重折叠的影响进行了调查。 | |||
TP1616 |
Hsp70-derived octapeptide
|
||
A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus | |||
T27128 |
DCB-3503
NSC716802,NSC 716802,NSC-716802,DCB3503,DCB 3503 |
||
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone | |||
T28266 |
Org-6906
Org6906,Org 6906,Org-6906 free |
||
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone |