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抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T41135	Defensin HNP-1 human
	Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis.
T41134	Defensin HNP-2 human
	Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.
T38103	Defensin HNP-3 (human) (trifluoroacetate salt)
	Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd...
T76501	Defensin HNP 4
	Defensin HNP 4，一种由11个氨基酸组成的HNP-41-11的片段，对多药耐药及非耐药菌株均显示出抑制效果。
T80045	Defensin HNP-3 human	Antibiotic	Microbiology/Virology
	Defensin HNP-3 human 是一种具有抑制金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌活性的细胞毒性抗生素肽。该肽原先以94个氨基酸的preproHNP(1-94)形式合成，随后水解为proHNP(20-94)，最终通过去除阴离子前体转化为成熟形式的HNP(65-94)。
T76070	Defensin HNP-1 human TFA
	Defensin HNP-1 human TFA，一种人中性粒细胞肽(HNPs)，在早期动脉粥样硬化发展中涉及内皮细胞功能障碍。该化合物展现出广泛的抗菌及抗利什曼原虫活性。
T4192	hnps-PLA Inhibitor	Phospholipase; LTR	Immunology/Inflammation; Metabolism
	hnps-PLA Inhibitor 是人类非胰腺分泌型磷脂酶 A (hnps-PLA) 的抑制剂。
T83641	HNPMI	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	HNPMI 是一种 EGFR 抑制剂，诱导 CRC 细胞的G0/G1 期停滞结直肠癌，可调节与细胞凋亡相关的酶，可促进细胞凋亡，可用于研究结直肠癌。

化合物

Defensin HNP-1 human

Cat.No: T41135

Synonym:

Target:

Defensin HNP-2 human

Cat.No: T41134

Synonym:

Target:

Defensin HNP-3 (human) (trifluoroacetate salt)

Defensin HNP-3 human

Cat.No: T80045

Synonym:

Target: Antibiotic

Defensin HNP-1 human TFA

Target: Phospholipase, LTR

HNPMI

Cat.No: T83641

Synonym:

Target: Apoptosis, EGFR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01992	Kallikrein 8/KLK8 Protein, Human, Recombinant (His) kallikrein-related peptidase 8,PRSS19,TADG14,NRPN,NP,HNP...	Human	HEK293 Cells
	Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. It is a serine protease that is capable of degrading some proteins such as casein, fibrinogen, kininogen, fibronectin, and collagen type IV. Kallikrein-8 / KLK8 plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-c...
TMPY-00346	DEFA3 Protein, Human, Recombinant (hFc) Defensin α3/DEFA3,defensin alpha 3,HP-3,HNP-3,DEF3,...	Human	HEK293 Cells
	DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666.
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His) HP-1,HNP-1,Defensin, alpha 1,DEFA1,DEFA2,MRS,Neutro...	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477.
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST) MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,Neutrophil defensi...	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665.