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Cat. No. | Product Name | Target | Signaling Pathways |
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T60748 |
ZDWX-25
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ZDWX-25 是 GSK-3β和 DYRK1A 的高效双重抑制剂,它对 SH-SY5Y 和 HL-7702 细胞显示出显著的细胞毒性。ZDWX-25 可用于研究阿尔茨海默症,其对 GSK-3β 的 IC50值为 71 nM。。 | |||
T36864 |
GRP (human) (trifluoroacetate salt)
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Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T3324 |
Lycorine
Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱 |
Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase | Apoptosis; Metabolism; Microbiology/Virology; Neuroscience |
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。 |