Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77792 |
HIV Peptide T
|
||
HIV Peptide T(Peptide T),这种合成的八肽是HIV感染治疗中的一种抗病毒药物,其主要通过竞争性抑制gp120(HIV表面蛋白)与CD4受体的相互作用,同时与血管肠肽(vasointestinal peptide, VIP)受体同源结合并且阻断细胞因子的产生与作用来发挥功效。 | |||
T7624 |
DAPTA
DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir |
HIV Protease; CCR | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
DAPTA (Adaptavir) 是一种合成肽,是 CCR5抑制剂,有抗 HIV 的活性。 | |||
TP1785L |
Peptide T acetate(106362-32-7 free base)
|
Others; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
Peptide T acetate(106362-32-7 free base) 是一种来自 HIV-1 gp120 V2 区域的八肽。它是一种合成八肽,其可能的作用机制是 gp120 对 CD4 受体的竞争性抑制以及与血管肠肽受体的结合和抑制细胞因子作用。 | |||
TP2401 |
Peptide T amide
D-Ala(1)-peptide T amide |
||
Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy. | |||
TP1873 |
Peptide T TFA
|
||
Peptide T (TFA) is an octapeptide derived from the V2 region of HIV-1 gp120. It serves as a ligand for the CD4 receptor, effectively inhibiting the binding of HIV to the CD4 receptor. | |||
TP1785 |
Peptide T
|
||
Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and in | |||
TP1743 |
MPG, HIV related
|
||
MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells. | |||
T76292 |
Tifuvirtide
|
||
Tifuvirtide (T-1249) 是一种肽类人类免疫缺陷病毒 1 型(HIV-1)融合抑制剂。Tifuvirtide 是一种合成设计的杂合逆转录病毒包膜多肽。Tifuvirtide 具有抗逆转录病毒活性。Tifuvirtide 可用于HIV 感染的研究。 | |||
T81431 |
Pol (476-484), HIV-1 RT Epitope
|
||
Pol (476-484),HIV-1RT Epitope 是具有生物活性的肽,对应逆转录酶 (RT) 的主要HLA A*0201限制性表位(Pol 残基 476-484)。其在HIV-1 RT中的角色涉及分析CTL逃逸机制。实际表位IV9在HIV-1感染的细胞系中被加工和呈现。 | |||
T37468 |
Siamycin I
|
||
Siamycin I is a tricyclic peptide originally isolated from Streptomyces and has antiviral and antibacterial activities. It is active against laboratory strains and clinical isolates of HIV-1 (ED50s = 0.05-0.45 and 0.89-5.7 μM, respectively), as well as the CBL-20 strain of HIV-2 (ED50 = 0.45 μM), in vitro. Siamycin I inhibits HIV-induced fusion of C8166 T cells with HIV-1-infected CEM-SS cells with an ED50 value of 0.08 μM. It is also active against B. subtilis, M. luteus, and S. aureus (MICs = ... | |||
T37874 |
Feglymycin
|
||
Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replication in H9 cells (IC50 = ~5 μM). Feglymycin is also active against clinical isolates of HIV-1 from clades A-D, A/E, and G (EC50s = 0.5-6.7 μM). It interacts with gp120 and inhibits HIV-1 NL4.3 binding to human soluble CD4 (EC50 = 4.4 μM) and to CD4+ SupT1 T cells by 74.5% when us... |