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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3185 |
R112
(E)-Elafibranor |
Syk | Angiogenesis; Tyrosine Kinase/Adaptors |
R112 ((E)-Elafibranor) 是ATP 竞争性的 Syk 激酶抑制剂,它能够抑制Syk 激酶活性,Ki=6 nM,IC50=226 nM。 | |||
T8699 |
GFT505
Elafibranor |
PPAR | DNA Damage/DNA Repair; Metabolism |
GFT505 (Elafibranor) 是一种 PPARα/δ 激动剂,EC50 分别为 45 和 175 nM。 | |||
T4408 |
Elafibranor
GFT505 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Elafibranor (GFT505) 是过氧化物酶体增殖物激活受体-α (PPAR-α) 和过氧化物酶体增殖物激活受体-δ (PPAR-δ) 的激动剂,EC50 值分别为 45 和 175 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01065 |
GM-CSFR alpha Protein, Human, Recombinant (His)
GM-CSF-R-α,colony stimul... |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1. | |||
TMPK-00930 |
GM-CSFR alpha Protein, Mouse, Recombinant (His)
CSF2RAX,CSF2RX,CD116, |
Mouse | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian... | |||
TMPK-00490 |
GM-CSFR alpha Protein, Cynomolgus, Recombinant (His)
CSF2RY,SMDP4,GMCSFR<... |
Cynomolgus | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mamm... | |||
TMPK-00254 |
GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated
GM-CSF-R-α,GM |
Human | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed... | |||
TMPY-00816 |
GM-CSFR alpha Protein, Human, Recombinant (hFc)
CSF2RAX,CSF2R,CD116,... |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1. |