Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11397 |
GGTI298
|
Others | Others |
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively. | |||
T6844 |
GGTI298 Trifluoroacetate
GGTI 298,GGTI 298 TFA salt |
Apoptosis; Transferase; Ras | Apoptosis; GPCR/G Protein; MAPK; Metabolism |
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) 是一种GGTase I 抑制剂,能够抑制Rap1A 且IC50值为3μM,对Ha-Ras 的作用很小IC50值 > 20 μM。 |