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Search Results for " gcr "

Targets Recommended: 5-HT Receptor Opioid Receptor Adrenergic Receptor

1

抑制剂 & 化合物

1

TargetMol 试剂盒

5

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0128	HMGCR inhibitor kit HMGCR inhibitor kit

TargetMol 试剂盒

HMGCR inhibitor kit

Cat.No: CL0128

Cat. No.	Product Name	Target	Signaling Pathways
T31750	Faxeladol EM906,GCR 9905,EM 906,GCR-9905,EM-906,GCR9905	5-HT Receptor; Opioid Receptor; Adrenergic Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Faxeladol 是一种有效的肾上腺素能吸收抑制剂和 5-羟色胺重摄取抑制剂，是一种小分子 Opioid receptors激动剂，可用于研究神经系统疾病。

化合物

Cat.No: T31750

Synonym: EM906,GCR 9905,EM 906,GCR-9905,EM-906,GCR9905

Target: 5-HT Receptor, Opioid Receptor, Adrenergic Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06836	NR3C1 Protein, Human, Recombinant (His) GCCR,GRL,GR,nuclear receptor subfamily 3, group C, member 1 ...	Human	E. coli
	NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. NR3C1 is a transcriptional regulator of many drug-metabolizing enzymes and anti-inflammatory molecules. NR3C1 polymorphisms associate with obesi...
TMPY-03980	ECD Protein, Human, Recombinant (His & GST) HSGT1,ECD,GCR2,ecdysoneless cell cycle regulator	Human	Baculovirus Insect Cells
	ECD, also known as ecdysoneless homolog, belongs to the SGT1 family. It is highly expressed in muscle and heart. ECD is a novel promoter of mammalian cell cycle progression. This function is related to its ability to remove the repressive effects of Rb-family tumor suppressors on E2F transcription factors. It is a novel tumor-promoting factor that is differentially expressed in pancreatic cancer and potentially regulates glucose metabolism within cancer cells. ECD may also be a transcriptional ...
TMPH-00007	HMGCR Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
TMPH-02476	HMGCR Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.4 kDa and the accession number is Q01237.
TMPH-02221	TRIM24 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apopt...

重组蛋白

NR3C1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06836

Species: Human

Expression System: E. coli

ECD Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03980

Species: Human

Expression System: Baculovirus Insect Cells

HMGCR Protein, Human, Recombinant (His)

Cat.No: TMPH-00007

Species: Human

Expression System: E. coli

HMGCR Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02476

Species: Mouse

Expression System: E. coli

TRIM24 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02221

Species: Human

Expression System: E. coli

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