Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21405 |
Fluvastatin
Canef,XU-62320,Vastin,Cranoc,Lescol |
HMG-CoA Reductase | Metabolism |
Fluvastatin (XU-62320) 是一种具有高效性和竞争性的 HMG-CoA 还原酶抑制剂(IC50 :8 nM),可通过依赖 Nrf2 通路抑制血管平滑肌细胞免受氧化应激,用于降低血浆胆固醇水平和预防心血管疾病。 | |||
T12652 |
(Rac)-5-Keto Fluvastatin
5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin |
Others | Others |
(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) 是 Fluvastatin 的杂质,Fluvastatin 是一种 HMG-CoA 还原酶的抑制剂。 | |||
T1487 |
Fluvastatin sodium
XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt |
Ferroptosis; HMG-CoA Reductase; Autophagy | Apoptosis; Autophagy; Metabolism |
Fluvastatin sodium (Fluvastatin sodium salt) salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂,IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激,是一种常用的降胆固醇剂。 | |||
T39036 |
(3R,5S)-Fluvastatin
(3R,5S)-Fluvastatin,(3R,5S)-XU 62-320 free acid |
||
(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway. | |||
T21042 |
Fluvastatin Methyl Ester
|
||
Fluvastatin Methyl Ester is a precursor of Fluvastatin, a blocker of the enzyme HMG-CoA reductase in liver. | |||
T11306 |
Fluvastatin D6 sodium
XU 62-320 (D6) |
Others | Others |
Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium. | |||
T10129 |
(3S,5R)-Fluvastatin sodium
(3S,5R)-XU 62-320 |
Others | Others |
(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2- | |||
T10128 |
(3S,5R)-Fluvastatin D6 sodium
(3S,5R)-XU 62-320 D6 |
Others | Others |
(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). | |||
T71628 | Fluvastatin potassium | ||
Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class. | |||
T71626 |
Epibestatin Hydrochloride
|
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Epibestatin Hydrochloride is a stabilizer of 14-3-3 PPIs, as well as a diastereoepimer of aminopeptidase inhibitor bestatin. |