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Search Results for " frt "

Targets Recommended: CFTR Autophagy

2

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T2595	Lumacaftor 鲁玛卡托,VX-809,VRT 826809	CFTR; Autophagy	Autophagy; Membrane transporter/Ion channel
	Lumacaftor (VRT 826809) 是一种 CFTR 调节剂，可纠正 CFTR 蛋白的折叠和运输。它增强了 FRT 细胞中 F508del-CFTR 蛋白的成熟，EC50为100 nM。
T10591L	(R)-BPO-27	CFTR; Autophagy	Autophagy; Membrane transporter/Ion channel
	(R)-BPO-27 是一种具有口服活性和高效性的 ATP 竞争性 CFTR 抑制剂(IC50：4 nM)，可用于研究腹泻和多囊肾。

化合物

Cat.No: T2595

Synonym: 鲁玛卡托,VX-809,VRT 826809

Target: CFTR, Autophagy

Cat.No: T10591L

Target: CFTR, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
TN1834	Kobusin 去甲槟郎碱,自旋七叶素	Others; NOS; NF-κB	Immunology/Inflammation; NF-κB; Others
	Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-express...

天然产物

Cat.No: TN1834

Synonym: 去甲槟郎碱,自旋七叶素

Target: Others, NOS, NF-κB

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Vascular endothelial growth factor receptor 1,Vascular perme...	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPK-00450	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) FLT1,FRT,FLT,Flt-1,VEGF R1,VEGFR1	Human	HEK293 Cells
	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.
TMPK-00451	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated FLT,Flt-1,FRT,VEGFR1,VEGF R1,FLT1	Human	HEK293 Cells
	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.

重组蛋白

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00412

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00450

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00451

Species: Human

Expression System: HEK293 Cells

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