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抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T73277	FABP-IN-2
	FABP-IN-2 是一种新型的 FABP3配体。FABP-IN-2 抑制 FABP3/FABP4 的 IC50分别为 1.16 μM 和 4.27 μM。
T4534	BMS-309403	FABP	Metabolism
	BMS309403 是有效的、选择性脂肪细胞脂肪酸结合蛋白 aFABP 抑制剂。它可改善载脂蛋白 E 缺乏症小鼠和培养的人内皮细胞的内皮功能。它能够与蛋白质内部的脂肪酸结合口袋相互作用，竞争性地抑制内源性脂肪酸的结合。
T37614	LDN-0088050
	LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1]. Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]Kd: 2.05 μM (FABP4)[1] LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1]. [1]. Zhou Y, et al. The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biolo...
T78960	FABP4-IN-2	FABP	Metabolism
	FABP4-IN-2（Compd 10g）是一种选择性的口服活性FABP4抑制剂，其对FABP4的Ki值为0.51 μM，而对FABP3的Ki值为33.01 μM。该化合物适用于研究与炎症相关的疾病。
T76550	CooP
	CooP为一种针对线性胶质母细胞瘤的九肽，与胶质母细胞瘤细胞及其相关血管系统中的乳腺来源生长抑制剂/脂肪酸结合蛋白3 (FABP3) 发生结合。该化合物主要应用于化学疗法和多种纳米粒子的靶向递送。
T63355	BMS-309403 sodium
	BMS-309403 sodium 是一种有效的选择性脂肪细胞脂肪酸结合蛋白aFABP, 也称为FABP4，aP2抑制剂，对 FABP4，FABP3 和 FABP5 的Ki 分别为 <2 nM，250 nM，350 nM。BMS-309403 sodium 与蛋白质内部的脂肪酸结合口袋相互作用，竞争性地抑制内源性脂肪酸的结合。BMS-309403 sodium 可改善载脂蛋白E 缺乏症小鼠和培养的人内皮细胞的内皮功能。

化合物

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Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPJ-00785	FABP3 Protein, Human, Recombinant (His) H-FABP,FABP11,Fatty Acid-Binding Protein H...	Human	E. coli
	Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to p...
TMPY-02239	FABP3 Protein, Human, Recombinant O-FABP,M-FABP,FABP11,MDGI,fatty a...	Human	E. coli
	FABP3 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P05413.
TMPY-00605	FABP3 Protein, Mouse, Recombinant Fabph1,Fabph-1,Fabph4,fatty acid ...	Mouse	E. coli
	FABP3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.8 kDa and the accession number is P11404.
TMPH-03291	FABP3 Protein, Rat, Recombinant (His & Myc)	Rat	HEK293 Cells
	FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.