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Search Results for " enterococcus faecalis "

7

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T28898	T145 T 145,T-145
	T145 inhibits growth of Enterococcus faecalis, Staphylococcus aureus and Mycobacterium tuberculosis (Mtb) with sub μg/ml potencies that are potentially therapeutically valuable. T145 minimizes selection of spontaneous resistant mutants, a trait that prolo
T80283	cOB1 phermone
	cOB1 pheromone是一种细菌性信息素，其对多重耐药粪肠球菌V583表现出有效抑制作用。
T29531	ABT-719 HCl A-816719.1,A 816719.1,ABT-719,ABT719,ABT 719,ABT-719 hydrochloride
	ABT-719 is a 2-pyridinone antimicrobial agent that is more effective against Enterococcus faecalis strains than ciprofloxacin and vancomycin, which showed resistance to ciprofloxacin and vancomycin covering a range of MIC.
T26256	Teicoplanin aglycone TD-A3
	Teicoplanin aglycone is an antibacterial glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Enterococcus faecalis and methicillin-resistant Staphylococcus aureus.
T74269	Antibacterial agent 83
	Antibacterial agent 83 (compound 17h) 对各种耐万古霉素 Enterococcus faecalis(VRE) 和耐甲氧西林 Staphylococcus aureus(MRSA) 显示出有效的抗菌活性。Antibacterial agent 83 可以显着减少 MRSA 的生物膜形成，并表现出良好的选择性。Antibacterial agent 83 在人肝微粒体中代谢稳定。
T80192	Enterocin K1 EntK1
	Enterocin K1 (EntK1)是一种细菌素bacteriocin，同时也属于核糖体合成肽类。该化合物通过特异性与粪肠球菌Enterococcus faecalis的Eep蛋白结合发挥作用，对耐甲氧西林的粪肠球菌VRE表现出显著的抗菌活性。Enterocin K1主要用于研究与VRE感染相关的治疗策略。
T80376	GP-2B
	GP-2B是一种具有针对革兰氏阳性菌株抗菌活性的抗菌肽，其最小抑菌浓度(MIC)针对金黄色葡萄球菌和粪肠球菌为8-128μg/mL。

化合物

Cat.No: T28898

Synonym: T 145,T-145

Cat.No: T80283

Cat.No: T29531

Synonym: A-816719.1,A 816719.1,ABT-719,ABT719,ABT 719,ABT-719 hydrochloride

Teicoplanin aglycone

Cat.No: T26256

Synonym: TD-A3

Antibacterial agent 83

Cat.No: T74269

Cat.No: T80192

Synonym: EntK1

Cat.No: T80376

Cat. No.	Product Name	Target	Signaling Pathways
T2904	Sclareolide 香紫苏内酯,Norambreinolide	Others; Antibacterial	Microbiology/Virology; Others
	Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物，具有抗菌和细胞毒性作用。
T72250	4aα,7α,7aα-Nepetalactone
	4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性，抑制Escherichia coli，Pseudomonas aeruginosa，Staphylococcus aureus，Salmonella typhi 和Enterococcus faecalis。
TN2625	14-Deoxycoleon U	Antifection	Microbiology/Virology
	14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and
T75523	Wychimicin A
	Wychimicin A 是一种螺旋藻酸聚酮，可从罕见的放线菌 Actinocrispum wychmicini 菌株 MI503-AF4 中分离得到。Wychimicin A 具有强抗菌活性，显著抑制耐甲氧西林的金黄色葡萄球菌Staphylococcus. aureus(IC50=0.125-0.5 μg/mL) 和肠球菌Enterococcus. Faecalis/faecium(IC50=0.25 μg/mL)。
T75522	Wychimicin C
	Wychimicin C为源自罕见放线菌Actinocrispum wychmicini菌株MI503-AF4的螺旋藻酸聚酮类化合物。此化合物展现出卓越的抗菌效果，尤其对耐甲氧西林的Staphylococcus. aureus（IC50=0.125-0.5 μg/mL）和Enterococcus. Faecalis/faecium（IC50=0.125-0.25 μg/mL）展现显著的抑制活性。
TN4637	Neogrifolin	PARP; GSK-3; Akt; Caspase	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS and MG63 osteosarcoma cell lines; it exhibits inhibitory activity against nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells with the IC50value of 23.3 microM. Neogrifolin possesses antimicrobial activities against Bacillus cereus and Enterococcus faecalis, the MIC values of 20 and 0.5 microg/mL, respe...
TN4168	Grifolin	Others	Others
	Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proliferation of oligodendrocyte precurs

天然产物

Cat.No: T2904

Synonym: 香紫苏内酯,Norambreinolide

Target: Others, Antibacterial

4aα,7α,7aα-Nepetalactone

Cat.No: T72250

14-Deoxycoleon U

Cat.No: TN2625

Target: Antifection

Cat.No: T75523

Cat.No: T75522

Cat.No: TN4637

Target: PARP, GSK-3, Akt, Caspase

Cat.No: TN4168

Target: Others

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