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Search Results for " epha4 "

Targets Recommended: Ephrin Receptor

5

抑制剂 & 化合物

15

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1561	123C4	Ephrin Receptor	Tyrosine Kinase/Adaptors
	123C4 是选择性的、竞争性的受体酪氨酸激酶EPHA4激动剂，Ki 为 0.65 μM.
TP1895L1	KYL acetate(676657-00-4 free base)	Ephrin Receptor	Tyrosine Kinase/Adaptors
	KYL acetate(676657-00-4 free base) 是EphA4受体酪氨酸激酶抑制剂（Kd = 0.8 μM）；抑制 EphA4-EphrinA5 相互作用 (IC50 = 6.34 μM)。防止 AβO 诱导的突触损伤、树突棘丢失并防止海马 CA3-CA1 传输中 LTP 的阻断。在细胞培养基中表现出较长的半衰期（在 PC3 和 C2C12 培养基中分别为 8 和 12 小时）。它有神经保护作用。
TP1895	KYL peptide KYL
	KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
T73368	UniPR505	Ephrin Receptor	Tyrosine Kinase/Adaptors
	UniPR505 是一种有效的 EphA2 拮抗剂（IC50：0.95 µM），是一种具有抗血管生成作用的新型 3α-氨基甲酰氧基衍生物。
T37391	PSEM 308 hydrochloride
	PSAM (pharmacologically selective actuator module) agonist. Activates PSAML141F-GlyR chimeric ion channels. Inhibits activity of neurons expressing PSAML141F-GlyR in vivo and activates locus coeruleus noradrenergic neurons expressing PSAML141F,Y115F-5-HT3 ion channels. Recommended concentration for use in mice is 5 mg/kg or lower. Plasmid vectors for the transfection of cells with PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 are available from Addgene. Lovett-Barron et al (2012) Regulation of neu...

化合物

Cat.No: TP1561

Target: Ephrin Receptor

KYL acetate(676657-00-4 free base)

Cat.No: TP1895L1

Target: Ephrin Receptor

Cat.No: TP1895

Synonym: KYL

Cat.No: T73368

Target: Ephrin Receptor

PSEM 308 hydrochloride

Cat.No: T37391

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00404	EphA4 Protein, Human, Recombinant Ephrin type-A receptor 4,TYRO1,HEK8,EK8,EPH-like ki...	Human	HEK293 Cells
	EphA4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 60-80 KDa and the accession number is P54764.
TMPJ-00405	EphA4 Protein, Human, Recombinant (hFc) Ephrin type-A receptor 4,SEK,hEK8,TYRO1,Tyrosine-pr...	Human	HEK293 Cells
	EphA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P54764.
TMPY-02991	EphA4 Protein, Rat, Recombinant (hFc) EPH receptor A4	Rat	HEK293 Cells
	EphA4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.3 kDa and the accession number is D3ZZK3.
TMPY-01779	EphA4 Protein, Mouse, Recombinant (hFc) Sek,rb,Hek8,EPH receptor A4,Cek8,Tyro1,2900005C20Ri...	Mouse	HEK293 Cells
	EphA4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.3 kDa and the accession number is Q03137-1.
TMPY-02942	EphA4 Protein, Rhesus, Recombinant (hFc) EPH receptor A4	Rhesus	HEK293 Cells
	EphA4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.4kDa and the accession number is A0A8J8XFI3.
TMPY-01778	EphA4 Protein, Mouse, Recombinant (His) Sek1,Sek,Cek8,rb,EPH receptor A4,AI385584,...	Mouse	HEK293 Cells
	EphA4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q03137-1.
TMPY-03314	EphA4 Protein, Rhesus, Recombinant (His) EPH receptor A4	Rhesus	HEK293 Cells
	EphA4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is A0A8J8XFI3.
TMPY-02932	EphA4 Protein, Rat, Recombinant (His) EPH receptor A4	Rat	HEK293 Cells
	EphA4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is D3ZZK3.
TMPY-01486	EphA4 Protein, Human, Recombinant (His) EPH receptor A4,SEK,HEK8,TYRO1	Human	HEK293 Cells
	EphA4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is A1MA61.
TMPY-02066	EphA4 Protein, Human, Recombinant (His & hFc) EPH receptor A4,SEK,TYRO1,HEK8	Human	HEK293 Cells
	EphA4 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 86.5 kDa and the accession number is A1MA61.
TMPY-04485	EphA4 Protein, Human, Recombinant (aa 570-986, His & GST) EPH receptor A4,TYRO1,HEK8,SEK	Human	Baculovirus Insect Cells
	EphA4 Protein, Human, Recombinant (aa 570-986, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is P54764.
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc) EFL2,LERK-3,EFNA3,Ephrin-A3,EHK1-L,EPLG3,EFL-2,EHK1 Ligand,L...	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhe...
TMPJ-00088	EFNA1 Protein, Mouse, Recombinant (hFc & His) Epgl1,Epl1,Immediate early response protein B61,Lerk1,EPH-re...	Mouse	HEK293 Cells
	Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membran...
TMPJ-00085	EFNA4 Protein, Human, Recombinant (hFc & His) LERK-4,LERK4,EPH-Related Receptor Tyrosine...	Human	HEK293 Cells
	Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. Ephrin-A4 consists of approximately 125 amino acids and includes four invariant cysteines, It has been shown to bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. Ephrin-A4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional s...
TMPJ-00224	EFNB2 Protein, Mouse, Recombinant (hFc & His) Ephrin-B2,Htkl,Lerk5.,ELF-2,Epl5,Eplg5,EPH-related receptor ...	Mouse	HEK293 Cells
	Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The ephrins and EPH-related receptors contain the largest subfamily of receptor protein-tyrosine kinases and have been associated ...

重组蛋白

EphA4 Protein, Human, Recombinant

Cat.No: TMPJ-00404

Species: Human

Expression System: HEK293 Cells

EphA4 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00405

Species: Human

Expression System: HEK293 Cells

EphA4 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02991

Species: Rat

Expression System: HEK293 Cells

EphA4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01779

Species: Mouse

Expression System: HEK293 Cells

EphA4 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-02942

Species: Rhesus

Expression System: HEK293 Cells

EphA4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01778

Species: Mouse

Expression System: HEK293 Cells

EphA4 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03314

Species: Rhesus

Expression System: HEK293 Cells

EphA4 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02932

Species: Rat

Expression System: HEK293 Cells

EphA4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01486

Species: Human

Expression System: HEK293 Cells

EphA4 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-02066

Species: Human

Expression System: HEK293 Cells

EphA4 Protein, Human, Recombinant (aa 570-986, His & GST)

Cat.No: TMPY-04485

Species: Human

Expression System: Baculovirus Insect Cells

EFNA3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00114

Species: Mouse

Expression System: HEK293 Cells

EFNA1 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00088

Species: Mouse

Expression System: HEK293 Cells

EFNA4 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00085

Species: Human

Expression System: HEK293 Cells

EFNB2 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00224

Species: Mouse

Expression System: HEK293 Cells

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