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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9118 |
KEA1-97
|
Apoptosis; Others; Caspase | Apoptosis; Others; Proteases/Proteasome |
KEA1-97 是一种选择性硫氧还蛋白-半胱天冬酶 3相互作用干扰剂,IC50为10 μM。它在不影响硫氧还蛋白活性的情况下, 破坏硫氧还蛋白与 caspase 3 的相互作用,激活半胱天冬酶,诱导细胞凋亡。 | |||
T23603 |
ACEA1011
ACEA-1011,ACEA 1011 |
||
ACEA1011 is a glycine site NMDA receptor antagonist. It may have analgesic effects. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01234 |
CD69 Protein, Human, Recombinant (His)
BL-AC/P26,CLEC2C,GP32/28,AIM,CD69 molecule,MLR-3,EA... |
Human | HEK293 Cells |
CD69 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q07108. | |||
TMPK-01278 |
CD69 Protein, Cynomolgus, Recombinant (His)
CLEC2C,AIM,EA1,MLR-3,GP32,BL-AC,BL-AC/P26,... |
Cynomolgus | HEK293 Cells |
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits. | |||
TMPH-01656 |
MAGEA12 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines. | |||
TMPJ-01125 |
PEA15 Protein, Human, Recombinant
15 kDa Phosphoprotein Enriched in Astrocytes,PE... |
Human | E. coli |
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm... | |||
TMPH-01655 |
MAGEA10 Protein, Human, Recombinant (His)
|
Human | E. coli |
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. MAGEA10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 46.3 kDa and the accession number is P43363. | |||
TMPH-01654 |
MAGEA1 Protein, Human, Recombinant (His)
|
Human | P. pastoris (Yeast) |
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.3 kDa and the accession number... |