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Targets Recommended: Apoptosis Others Caspase

2

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9118 KEA1-97

Apoptosis; Others; Caspase Apoptosis; Others; Proteases/Proteasome
KEA1-97 是一种选择性硫氧还蛋白-半胱天冬酶 3相互作用干扰剂,IC50为10 μM。它在不影响硫氧还蛋白活性的情况下, 破坏硫氧还蛋白与 caspase 3 的相互作用,激活半胱天冬酶,诱导细胞凋亡。
T23603 ACEA1011

ACEA-1011,ACEA 1011

ACEA1011 is a glycine site NMDA receptor antagonist. It may have analgesic effects.

化合物

KEA1-97
Cat.No: T9118
Synonym:
Target: Apoptosis, Others, Caspase
ACEA1011
Cat.No: T23603
Synonym: ACEA-1011,ACEA 1011
Target:
Cat. No. Product Name Species Expression System
TMPY-01234 CD69 Protein, Human, Recombinant (His)

BL-AC/P26,CLEC2C,GP32/28,AIM,CD69 molecule,MLR-3,EA...

Human HEK293 Cells
CD69 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q07108.
TMPK-01278 CD69 Protein, Cynomolgus, Recombinant (His)

CLEC2C,AIM,EA1,MLR-3,GP32,BL-AC,BL-AC/P26,...

Cynomolgus HEK293 Cells
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits.
TMPH-01656 MAGEA12 Protein, Human, Recombinant (His & Myc)

Human E. coli
Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.
TMPJ-01125 PEA15 Protein, Human, Recombinant

15 kDa Phosphoprotein Enriched in Astrocytes,PE...

Human E. coli
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm...
TMPH-01655 MAGEA10 Protein, Human, Recombinant (His)

Human E. coli
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. MAGEA10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 46.3 kDa and the accession number is P43363.
TMPH-01654 MAGEA1 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.3 kDa and the accession number...

重组蛋白

CD69 Protein, Human, Recombinant (His)
Cat.No: TMPY-01234
Species: Human
Expression System: HEK293 Cells
CD69 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01278
Species: Cynomolgus
Expression System: HEK293 Cells
MAGEA12 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01656
Species: Human
Expression System: E. coli
PEA15 Protein, Human, Recombinant
Cat.No: TMPJ-01125
Species: Human
Expression System: E. coli
MAGEA10 Protein, Human, Recombinant (His)
Cat.No: TMPH-01655
Species: Human
Expression System: E. coli
MAGEA1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01654
Species: Human
Expression System: P. pastoris (Yeast)
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