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Search Results for " dalbergioidin "

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Cat. No.	Product Name	Target	Signaling Pathways
TN3753	Dalbergioidin	Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad	Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ...