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Cat. No. Product Name Target Signaling Pathways
T1120 Dacarbazine

Imidazole Carboxamide,达卡巴嗪,DTIC-Dome

Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Dacarbazine (DTIC-Dome) 是一种抗肿瘤剂,对黑色素瘤具有显着的活性。
T1120L Dacarbazine hydrochloride

Dacarbazine HCl

Dacarbazine ( imidazole carboxamide) is a chemotherapy drug used to treat melanoma and Hodgkin's lymphoma.
T1120L2 Dacarbazine citrate

DTIC citrate

Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Soft tissue sarcoma (cancer of muscles
T16433 Pancopride

LAS 30451

5-HT Receptor GPCR/G Protein; Neuroscience
Pancopride(LAS 30451) 是一种可口服的新型有长效的选择性 5-HT3 受体拮抗剂,可阻断氮芥和达卡巴嗪诱导的呕吐。
T71768 CB10-277

CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.
T60475 RRD-251

RRD-251 是一种(Rb)-Raf-1相互作用抑制剂,可诱导转移性黑色素瘤细胞凋亡并能与达卡巴嗪协同作用,具有抗增殖、抗血管生成和抗肿瘤活性。

化合物

Dacarbazine
Cat.No: T1120
Synonym: Imidazole Carboxamide,达卡巴嗪,DTIC-Dome
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Dacarbazine hydrochloride
Cat.No: T1120L
Synonym: Dacarbazine HCl
Target:
Dacarbazine citrate
Cat.No: T1120L2
Synonym: DTIC citrate
Target:
Pancopride
Cat.No: T16433
Synonym: LAS 30451
Target: 5-HT Receptor
CB10-277
Cat.No: T71768
Synonym:
Target:
RRD-251
Cat.No: T60475
Synonym:
Target:
TargetMol Loading
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