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3

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzymes, including the cytochrome P450 (CYP450) isoform CYP1B1, as well as microsomal epoxide hydrolase (mEH), producing a variety of reactive metabolites that form DNA adductsin vivo, and it has been commonly used to induce tumor formation in various rodent models.2,3,1DMBA increase...
T77506	1-vinylpyrene 1-Ethenylpyrene	Others	Others
	1-vinylpyrene (1-Ethenylpyrene) 具有抗肿瘤活性，以剂量依赖性方式强烈抑制由DMBA 或B[]P 引发的皮肤肿瘤的形成，可用于预防肿瘤形成。
T31842	Folligen
	Folligen is a novel gonadotropin-releasing hormone analog against DMBA-induced tumours in the rat.

化合物

Cat.No: T36696

Cat.No: T77506

Synonym: 1-Ethenylpyrene

Target: Others

Cat.No: T31842

Cat. No.	Product Name	Target	Signaling Pathways
T19775	Trilaurin Tridodecanoin,NSC 4061,Glyceryl tridodecanoate,Trilauroylglycerol,Glycerol trilaurate, Glyceryl trilaurate,甘油三酯,1,2,3-Tridodecanoylglycerol	Others	Others
	Trilaurin (Glyceryl tridodecanoate) 是一种存在于膳食脂肪中的甘油三酯。三月桂酸甘油酯可用作化妆品中的增稠剂。
TN4652	Niazimicin	NF-κB; PI3K; AChR; Antifection	Microbiology/Virology; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
	Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in the two-stage carcinogenesis in mouse skin using 7,12-dimethylbenz(a)anthracene (DMBA) as ini
TN4380	Karavilagenin D	Others	Others
	Karavilagenin D exhibits inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator, and with TPA as a promoter. It exhibits inhibition effect against human
TN4241	Hyptadienic acid
	Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells.It also shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz

天然产物

Cat.No: T19775

Synonym: Tridodecanoin,NSC 4061,Glyceryl tridodecanoate,Trilauroylglycerol,Glycerol trilaurate, Glyceryl trilaurate,甘油三酯,1,2,3-Tridodecanoylglycerol

Target: Others

Cat.No: TN4652

Target: NF-κB, PI3K, AChR, Antifection

Karavilagenin D

Cat.No: TN4380

Target: Others

Hyptadienic acid

Cat.No: TN4241

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