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4

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T15109 DGAT1-IN-1

Transferase Metabolism
DGAT1-IN-1DGAT1的高效抑制剂,在 Hep3B 细胞过表达 DGAT1裂解物中,测得IC50低于10nM。
T4681 T863

DGAT-3,DGAT-1 inhibitor

Acyltransferase; Transferase Metabolism
T863 (DGAT-3) 是口服有效的二酰基甘油酰基转移酶1 选择性抑制剂。T863结合DGAT1的酰基辅酶A 结合位点,抑制三酰甘油在细胞内的合成。
T62220 DGAT1-IN-3

DGAT1-IN-3 是一种选择性的、有效的,口服具有活力的 DGAT-1 抑制剂,能够抑制人类 DGAT-1 (IC50: 38 nM) 和大鼠 DGAT-1 (IC50: 120 nM)。DGAT1-IN-3 能够用于肥胖、血脂异常和代谢综合征的研究。
T71886 ALN29882

ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant p...

化合物

DGAT1-IN-1
Cat.No: T15109
Synonym:
Target: Transferase
T863
Cat.No: T4681
Synonym: DGAT-3,DGAT-1 inhibitor
Target: Acyltransferase, Transferase
DGAT1-IN-3
Cat.No: T62220
Synonym:
Target:
ALN29882
Cat.No: T71886
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T37690 Phenylpyropene A

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ...

天然产物

Phenylpyropene A
Cat.No: T37690
Synonym:
Target:
TargetMol Loading
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