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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16867 |
SEC inhibitor KL-1
KL-1 |
Others | Others |
SEC inhibitor KL-1 (KL-1) 是一种拟肽先导化合物,是一种有效的选择性SEC 抑制剂,能够剂量依赖性地抑制 AFF4-CCNT1 相互作用。它能够破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用,导致 Pol II 从启动子近端暂停位点的释放受损,并且进行性转录延伸的平均速率降低。 | |||
T2292 |
FPH2
BRD-9424 |
Others | Others |
FPH2 (BRD-9424) 是促进 iPS 衍生肝细胞分化的小分子。它诱导原代人肝细胞的功能性增殖,有潜质用于研究肝脏疾病的新疗法。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02170 |
SCF Protein, Human, Recombinant (aa 1-189, His)
DCUA,Kitl,FPHH,SCF,KL-1,SF,FPH2,MGF,SHEP7,C-kit lig... |
Human | Baculovirus Insect Cells |
SCF Protein, Human, Recombinant (aa 1-189, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is P21583-1. | |||
TMPY-05135 |
SCF Protein, Mouse, Recombinant (His), Biotinylated
Con,SLF,SF,Mgf,Gb,Clo,KIT ligand,Sl,Kitlg,SCF |
Mouse | Baculovirus Insect Cells |
SCF Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is P20826-1. | |||
TMPJ-00166 |
SCF Protein, Mouse, Recombinant
SCF,Hematopoietic growth factor KL,MGF,Steel factor,Mast cel... |
Mouse | E. coli |
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the ... | |||
TMPJ-00375 |
HGF Protein, Human, Recombinant (His)
Scatter factor,Hepatocyte growth factor,HGF,SF,Hepatopoietin... |
Human | HEK293 Cells |
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia... |