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Cat. No. Product Name Target Signaling Pathways
T10972 DC4

Others Others
DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors.
T4051 LDC4297

LDC044297

CDK; HSV Cell Cycle/Checkpoint; Microbiology/Virology
LDC4297 (LDC044297)是 CDK7的一种高效选择性抑制剂,IC50值为0.13 nM。
T10976 DC4SMe

Others Others
The IC50s of DC4SMe on Ramos, Namalwa and HL60 / s cancer cells were 1.9 nM, 2.9 nM and 1.8 nM, respectively. DC4SMe can be used for targeted therapy of tumors. DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the
T10975 DC44SMe

Others Others
The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug co
T72385 LDC4297 hydrochloride

LDC4297 hydrochloride为CDK7选择性抑制剂,IC50为0.13 nM。针对人巨细胞病毒(HCMV)复制展现抑制作用,EC50为24.5 nM,并对疱疹病毒、腺病毒、痘病毒、逆转录病毒及正粘病毒显示广谱抗病毒活性,EC50范围0.02-1.21 μM。适用于感染研究。
T10974 DC41

Others Others
DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer.
T83713 DC432 TFA

DC432是一种细胞内可渗透的肽类抑制剂,针对N-末端Xaa-Pro-Lys N-甲基转移酶1 (NTMT1; IC50 = 0.054 µM)。该化合物与NTMT1和NTMT2有结合作用(Kds分别为0.3和1 µM),并在10和50 µM的浓度下,通过细胞外实验抑制NTMT1对调节染色体凝缩1 (RCC1) N-末端二甲基化。DC432(100 µM)在HCT116细胞中减少了RCC1 SPKRIA基序的三甲基化。
T10973 DC41SMe

Others Others
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer.

化合物

DC4
Cat.No: T10972
Synonym:
Target: Others
LDC4297
Cat.No: T4051
Synonym: LDC044297
Target: CDK, HSV
DC4SMe
Cat.No: T10976
Synonym:
Target: Others
DC44SMe
Cat.No: T10975
Synonym:
Target: Others
LDC4297 hydrochloride
Cat.No: T72385
Synonym:
Target:
DC41
Cat.No: T10974
Synonym:
Target: Others
DC432 TFA
Cat.No: T83713
Synonym:
Target:
DC41SMe
Cat.No: T10973
Synonym:
Target: Others
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