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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T35383	Cysteamine bitartrate Mercaptamine bitartrate	Others	Others
	Cysteamine bitartrate (Mercaptamine bitartrate)是FDA 批准的胱氨酸消耗氨基硫醇药物(cystine-depleting aminothiol agent)，通过参与二硫交换减少溶酶体胱氨酸的积累，用于治疗肾病性胱氨酸病。此外，Cysteamine bitartrate 还具有抗氧化特性。
T19106	2-(Pyridyldithio)ethylamine hydrochloride 2-(2-吡啶基二硫基)乙胺盐酸盐,(S)-2-Pyridylthio Cysteamine Hydrochloride	Others	Others
	2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) 是新型的二硫化物插入交联剂。
T81516	Pep-1-Cysteamine
	Pep-1-Cysteamine为一种初级两亲性CPP，能够跨生物膜转移，将活性蛋白质导入细胞内。
T75128	I-152
	I-152是一种共轭物，含N-乙酰半胱氨酸(NAC)与半胱胺(MEA)。该化合物能激活NRF2和ATF4信号，具抗增殖活性。
T24254	KB-5492 anhydrous KB-5492,KB5492,KB 5492
	KB 5492 is an agent of anti-ulcer. It preventing cysteamine-induced duodenal ulcers by stimulating duodenal HCO3- secretion.
T37002	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)
	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emission maxima of 380/515 nm, respectively.1 1.Imai, K., Toyo’oka, T., and Watanabe, Y.A novel fluorogenic reagent for thiols: Ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonateAnal. Biochem.128(2)471-473(1983) 2.Ichinose, S., Nakamura, M., Maeda, M., et al.A validated HPLC-fluoresc...

化合物

Cysteamine bitartrate

Cat.No: T35383

Synonym: Mercaptamine bitartrate

Target: Others

2-(Pyridyldithio)ethylamine hydrochloride

Cat.No: T19106

Synonym: 2-(2-吡啶基二硫基)乙胺盐酸盐,(S)-2-Pyridylthio Cysteamine Hydrochloride

Synonym: KB-5492,KB5492,KB 5492

Target:

7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)

Cat.No: T37002

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T6460	Cysteamine hydrochloride 2-Mercaptoethylamine Hydrochloride,β-Mercaptoethylamine Hydrochloride,半胱胺盐酸盐,Thioethanolamine Hydrochloride,2-Aminoethanethiol Hydrochloride,Cysteamine HCl,Bekaptan	Apoptosis; Others; Reactive Oxygen Species; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; Others
	Cysteamine hydrochloride (Thioethanolamine Hydrochloride) 是一种可口服的，用于肾病型胱胺酸症的小分子药物，也可作为抗氧化剂。
T1080	2-Aminoethanethiol 2-Mercaptoethylamine,巯基乙胺,β-Mercaptoethylamine,β-MEA,Cysteamine	Apoptosis; Others; Reactive Oxygen Species; Cysteine Protease; Somatostatin; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Others; Proteases/Proteasome
	2-Aminoethanethiol (Cysteamine) 是一种胱氨酸消耗剂。半胱胺的作用机制是胱氨酸二硫化物还原。