Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6503 |
Fluorometholone Acetate
NSC 47438,Flarex,Eflone,氟米龙醋酸酯,Oxylone acetate |
Glucocorticoid Receptor; Carbonic Anhydrase | Endocrinology/Hormones; Metabolism |
Fluorometholone Acetate (Oxylone acetate) 是合成的糖皮质激素皮质类固醇及皮质类固醇酯。它有效抑制碳酸酐酶 (CA) 对 hCA-I(IC50:2.18 μM)和 hCA-II(IC50:17.5 μM)。它具有抗炎活性,可用于研究外部眼部炎症。 | |||
T0378 |
Oxybuprocaine hydrochloride
Risedronic Acid,Oxybuprocaine HCl,奥布卡因盐酸盐 |
Sodium Channel | Membrane transporter/Ion channel |
Oxybuprocaine hydrochloride (Oxybuprocaine HCl) 是可逆的钠通道阻断剂,可防止角膜,结膜和巩膜中疼痛神经的冲动传播。Oxybuprocaine hydrochloride 专用于眼科与耳鼻喉科。 | |||
T3316 |
Fluorometholone
氟米龙,Fluoromethalone,Cortilet,Oxylone,Delmeson |
Glucocorticoid Receptor | Endocrinology/Hormones |
Fluorometholone (Fluoromethalone) 是合成糖皮质激素,具有抗炎和抗过敏作用。它可用作糖皮质激素受体激动剂,能够用于干眼症的研究。 | |||
T68957 |
Eprociclovir dihydrate
|
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Eprociclovir dihydrate is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica... | |||
T75857 |
LL-37, human TFA
|
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LL-37, human TFA 是一种由37个氨基酸残基组成的两亲性抗菌肽,源自组织蛋白酶,具备广谱抗菌活性。该化合物有助于防护角膜避免感染,同时调节伤口的愈合过程。 | |||
T37930 |
15(R)-17-phenyl trinor Prostaglandin F2α
15(R)-17-phenyl trinor Prostaglandin F2α |
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17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hours. The free acid, 17-ph... | |||
T75858 |
LL-37, human acetate
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LL-37, human acetate 是一种由37个氨基酸残基组成的两亲性抗菌肽,源于组织蛋白酶的衍生物,展现出广泛的抗菌效果。该化合物不仅对角膜感染提供保护,也有助于调节伤口的愈合过程。 | |||
T70027 | Eprociclovir potassium | ||
Eprociclovir potassium is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica... | |||
T75837 |
Spantide I TFA
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Spantide I TFA 是substance P 的类似物,是选择性的神经激肽-1 受体 (NK1receptor) 的拮抗剂,其对NK1和NK2受体的Ki 值分别为 230 nM 和8150 nM。Spantide I 可减少感染角膜的1型细胞因子和增强2型细胞因子IL-10,从而显著减少角膜穿孔。 | |||
T69817 |
Eprociclovir Na
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Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applie... |