10
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4020 |
Cadazolid
ACT-179811,卡达唑利德 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cadazolid (ACT-179811) 是一种新型恶唑烷酮类抗生素,对Clostridium difficile 有活性。 | |||
T12337L |
Oxaquin TEA
MCB-3837 TEA,Oxaquin TEA(790704-50-6 Free base),DNV3837 TEA |
Topoisomerase; Antifungal | DNA Damage/DNA Repair; Microbiology/Virology |
Oxaquin TEA (MCB-3837 TEA) 是 MCB3681 的前体化合物,是一种 DNA 拓扑异构酶抑制剂,可用于研究梭菌感染和交叉感染。 | |||
T7735 |
5-Nitro-1,10-phenanthroline
5-NP,5-硝基-1,10-菲咯啉 |
Antibacterial | Microbiology/Virology |
5-Nitro-1,10-phenanthroline (5-NP) 是一种有效的杀菌剂,可抑制艰难梭菌。 | |||
T79774 |
Antibacterial agent 159
|
Antibiotic | Microbiology/Virology |
Antibacterialagent 159 (Compound 6d) 是一款高效抗菌化合物,具备针对脓疱疮和C. difficile感染(CDI)的抗菌活性。其使用过程中未发现C. difficile复发现象,并对益生肠道菌群仅有微弱影响。 | |||
T76806 | Bezlotoxumab | ||
Bezlotoxumab 是一种针对 C. difficile 毒素 B 的人单克隆抗体。Bezlotoxumab 与 C. difficile 毒素 B 结合,可预防肠上皮损伤和结肠炎。 | |||
T80417 |
Cacaoidin
|
||
Cacaoidin是一种糖基化抗生素,从可可链霉菌菌株中分离得到,对革兰氏阳性病原菌(包括艰难梭菌)展示出较强的抗菌活性。 | |||
T73601 | Penicillin V | ||
Penicillin V (Phenoxymethylpenicillin) 是一种具口服活性的有效抗生素,对链球菌、艰难梭菌以及金黄色葡萄球菌展现出良好的抗菌效果。此外,Penicillin V 在耳炎、鼻窦炎、咽炎及扁桃体炎方面的治疗潜力[4],亦在研究之中。 | |||
T79773 |
Antibacterial agent 158
|
||
Antibacterialagent 158 (compound 6c) 是一种高效抗菌化合物,具有显著的抗微球菌以及对抗脓疱疮和艰难梭菌感染 (CDI) 的活性。 | |||
T36075 |
Cholic Acid anilide
|
||
Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).1 |1. Sharma, S.K., Yip, C., Esposito, E.X., et al. The design, synthesis, and characterizations of spore germination inhibitors effective against an epidemic strain of Clostridium difficile. J. Med. Chem. 61(15), 6759-6778 (2018). | |||
T65598 | Cefminox sodium | ||
Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6194 |
Fidaxomicin
非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 |
Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Fidaxomicin (Tiacumicin B) 是一种大环RNA 聚合酶抑制剂,具有窄谱活性。它选择性地根除致病性艰难梭菌,对构成正常健康肠道菌群的多种细菌影响很小。 |