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Search Results for " citrulline "

13

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP2493	Tripeptide-10 citrulline Acetate Tripeptide-10 citrulline Acetate(960531-53-7 Free base)	Others	Others
	Tripeptide-10 citrulline Acetate (Tripeptide-10 citrulline Acetate) 已被证明具有抗皱和美容效果。
T36104	Citrulline-specific Probe-Rhodamine
	Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has been observed in a host of human diseases. Citrulline-specific probe-rhodamine is a highly sensitive, rhodamine phenylglyoxal-based fluorophore that specifically detects protein citrullination via a chemoselective reaction between glyoxal and citrulline. This chemical probe (com...
T80944	Tripeptide-10 citrulline T10-C
	Tripeptide-10 citrulline(T10-C)，一种生物活性肽，具备抗衰老(anti-aging)功能，广泛应用于化妆品成分。
T3503	MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂	Others; AChR	Neuroscience; Others
	MC-Val-Cit-PABC-PNP 是一种组织蛋白酶可裂解的 ADC 肽接头，可用于合成抗体偶联药物。
T83196	Acetyl tripeptide-30 citrulline
	Acetyl tripeptide-30，一种生物活性肽，具备显著的抗皱功效，常见于化妆品成分中。
T18870	Vc-MMAD	Others	Others
	Vc-MMAD 由 linker (Val-Cit) 和微管抑制剂 MMAD 组成。Vc-MMAD 可用于偶联抗体。
T30127	Argininosuccinic acid
	Argininosuccinic acid can be obtained during the urea cycle from citrulline, aspartate, and ATP by argininosuccinic acid synthetase.
TP1409	CCP peptide
	CCP peptide is a synthetic cyclic peptide incorporating the amino acid citrulline.
T77827	DBCO-PEG4-acetic-Val-Cit-PAB
	DBCO-PEG4-acetic-Val-Cit-PAB为含四单元聚乙二醇（PEG）的ADC可分解连接体，适用于合成抗体药物偶联物（ADC）。
T78044	α-Methyl-DL-aspartic acid
	α-Methyl-DL-aspartic acid为特异性抑制剂，针对精氨酸琥珀酸合成酶(ASS)，亦作用于1-瓜氨酸向1-精氨酸循环的限速酶。
T77864	SC239
	SC239为一种2-氨基苯基半紫杉烷类活性分子连接剂，具有可裂解特性。该化合物适用于抗体药物偶联物（ADC）的活性分子连接。
T83671	CCP-biotin Peptide (non-cyclized) Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized)
	CCP-biotin Peptide（非环化）是一种生物素化且非环化的圆形瓜氨酸化肽（CCP）版本。该序列对应于人类filaggrin的447-467氨基酸，但包含Q447H、S449C、G459R、E460G和S462C的替换，并在455位的精氨酸处发生了瓜氨酸化。CCP-biotin Peptide（非环化）旨在用于检测可能与线性肽结合的抗瓜氨酸自身抗体。
T35817	Photoswitchable PAD Inhibitor (technical grade)
	Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without photoactivation, it is a weak inhibitor of PAD2 (IC50 = >100 μM) and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro (kinact/KIs = 2,300, 600, 1,000, and 10,510 M-1min-1 for PAD1-4, respectively) and does not inhibit histone H3 citrullination in HEK29...

化合物

Tripeptide-10 citrulline Acetate

Cat.No: TP2493

Synonym: Tripeptide-10 citrulline Acetate(960531-53-7 Free base)

Target: Others

Citrulline-specific Probe-Rhodamine

Cat.No: T36104

Tripeptide-10 citrulline

Cat.No: T80944

Synonym: T10-C

MC-Val-Cit-PABC-PNP

Cat.No: T3503

Synonym: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂

Target: Others, AChR

Acetyl tripeptide-30 citrulline

Cat.No: T83196

Cat.No: T18870

Target: Others

Argininosuccinic acid

Cat.No: T30127

Cat.No: TP1409

DBCO-PEG4-acetic-Val-Cit-PAB

Cat.No: T77827

α-Methyl-DL-aspartic acid

Cat.No: T78044

Cat.No: T77864

CCP-biotin Peptide (non-cyclized)

Cat.No: T83671

Synonym: Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized),Cyclic Citrullinated Peptide-biotin Peptide (non-cyclized)

Photoswitchable PAD Inhibitor (technical grade)

Cat.No: T35817

Cat. No.	Product Name	Target	Signaling Pathways
T4813	L-Citrulline	Endogenous Metabolite	Metabolism
	L-Citrulline 是一种氨基酸，源自于精氨酸-瓜氨酸途径获得的 l-精氨酸，或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T2931	2-Amino-5-ureidopentanoic acid DL-Citrulline,Citrulline,瓜氨酸	Others; Endogenous Metabolite	Metabolism; Others
	2-Amino-5-ureidopentanoic acid (Citrulline) 存在于肝脏中，不是蛋白质的构成成分，为人体脲循环的一个重要中间物，可与鸟氨酸、精氨酸合用治疗高氨血症。
T20200	Citrulline malate L-Citrulline DL-malate,Stimol
	Citrulline malate is a cpd of anti-fatigue.
T5257	L-Homocitrulline 高瓜氨酸,Homo-L-citrulline,Homocitrulline	Others; Endogenous Metabolite	Metabolism; Others
	L-Homocitrulline (Homocitrulline) 是一种代谢物，可在尿素循环障碍患者的尿液中大量检测到。在某些情况下，由于尿素循环的鸟氨酸供应耗尽而导致的氨甲酰磷酸酯的积累可能是 L-Homocitrulline 和高精氨酸合成增强的原因。
T3S0364	L-Arginine L-精氨酸,L-Arg,(S)-(+)-Arginine	IL Receptor; Endogenous Metabolite; NO Synthase	Immunology/Inflammation; Metabolism
	L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞，并被代谢成一氧化氮、多胺或 L-脯氨酸。
TN3616	Cedrelone	Apoptosis; MMP; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Cedrelone 是一种柠檬苦素类化合物，是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂，它能导致细胞周期停止。Cedrelone 具有杀虫活性，可抑制 P. saucia 的箭毒生长，并可抑制乳草蝽（Oncopeltus fasciatus）的蜕皮。Cedrelone具有抗肿瘤作用，对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。

天然产物

Cat.No: T4813

Target: Endogenous Metabolite

2-Amino-5-ureidopentanoic acid

Cat.No: T2931

Synonym: DL-Citrulline,Citrulline,瓜氨酸

Target: Others, Endogenous Metabolite

Citrulline malate

Cat.No: T20200

Synonym: L-Citrulline DL-malate,Stimol

L-Homocitrulline

Cat.No: T5257

Synonym: 高瓜氨酸,Homo-L-citrulline,Homocitrulline

Target: Others, Endogenous Metabolite

Cat.No: T3S0364

Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

Cat.No: TN3616

Target: Apoptosis, MMP, Antifection

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