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Search Results for " cgrp "

Targets Recommended: CGRP Receptor CGRP Receptor

51

抑制剂 & 化合物

2

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1323	CGRP 8-37 (rat)	CGRP Receptor	GPCR/G Protein; Neuroscience
	CGRP 8-37 (rat) 是 CGRP receptor 拮抗剂，是一种可作用于大鼠的 CGRP片段，具有潜在的抗伤害作用，可诱导动脉松弛。
TP2233L	CGRP (rat) acetate	Others	Others
	CGRP (rat) acetate 是一种降钙素基因相关肽（CGRP）。它是一种有效的血管扩张剂。
T13453	CGRP antagonist 1	CGRP Receptor	GPCR/G Protein; Neuroscience
	CGRP antagonist 1是高效 CGRP 受体拮抗剂，Ki 值分别为 35nM，IC50 值为 57 nM。CGRP antagonist 1可用于研究心血管疾病和神经血管疾病。
TP2044L	α-CGRP (human) acetate 人类降钙素基因相关肽 1,α-CGRP (human) acetate (90954-53-3 free base)	Others	Others
	α-CGRP (human) acetate 是一种由 37 个氨基酸组成的调节性神经肽。它是一种有效的血管扩张剂，具有正性肌力作用和变时性作用。
TP1200	CGRP (83-119), rat TFA Calcitonin Gene Related Peptide(83-119), rat TFA	Others	Others
	CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族，通过降钙素受体样受体起作用。
TP1130	β-CGRP, human CGRP-II (Human),Human β-CGRP
	β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal
TP2233	α-CGRP, rat CGRP (rat)	Others	Others
	Endogenous neuropeptide, potent vasodilator
TP2044	α-CGRP(human) α-CGRP (human)
	Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
TP1202	Calcitonin Gene Related Peptide (CGRP) II, rat CGRP II, rat
	Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
TP1203	CGRP(83-119), rat Calcitonin Gene Related Peptide (CGRP) (83-119), rat
	Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1131	β-CGRP, human TFA (101462-82-2 free base) CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
	β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.
TP1201	CGRP II, rat (TFA) (99889-63-1 free base) Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
	Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T38190	Tyr-α-CGRP (rat) (trifluoroacetate salt)
	Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.
T36555	Tyr-α-CGRP (human) (trifluoroacetate salt)
	Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig...
TP1134	HCGRP-(8-37) Human α-CGRP (8-37)
	Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
T75978	β-CGRP, human TFA
	β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽，通过降钙素受体样受体CRLR 与RAMP 的复合物起作用，在细胞体系中，对 CRLR/RAMP1 和 CRLR/RAMP2 的IC50值分别为 1 nM 和 300 nM。
T75732	α-CGRP, rat TFA
	α-CGRP, rat TFA 是一种神经肽 (降钙素基因相关肽)，主要表达于神经肌肉交界处，是一种有效的血管扩张剂量。α-CGRP, rat TFA 外周给药可使大鼠血压下降、心率升高，并使结肠平滑肌松弛。α-CGRP, rat TFA 可用于心血管、促炎、偏头痛和代谢相关的研究。
T75788	α-CGRP(human) TFA
	α-CGRP(human) TFA，一种含37个氨基酸的调节性神经肽，广泛存在于中枢神经系统和周围神经系统中，是一种高效的血管扩张剂。
T78540	α-CGRP (mouse, rat) TFA	CGRP Receptor	GPCR/G Protein; Neuroscience
	α-CGRP (mouse, rat) TFA 是神经系统中的一种活性神经肽，位于神经肌肉接合部，具有显著的血管舒张功能。适用于心血管疾病、炎症、偏头痛及代谢研究领域。
T8682	Vazegepant hydrochloride Vazegepant HCl	CGRP Receptor	GPCR/G Protein; Neuroscience
	Vazegepant hydrochloride (Vazegepant HCl) 是一种用于偏头痛的鼻用 gepant，是一种高度亲和性CGRP 受体拮抗剂 (hCGRPKi=0.023 nM)。它可能有助于有效管理 COVID-19 相关肺部炎症。
T17194	Ubrogepant MK-1602	CGRP Receptor	GPCR/G Protein; Neuroscience
	Ubrogepant (MK-1602) 是新型的、口服有效的降钙素基因相关肽受体拮抗剂。Ubrogepant 有潜力用于急性偏头痛的相关研究。
T76032	Calcitonin Gene Related Peptide (CGRP) II, rat TFA
	CalcitoninGene Related Peptide (CGRP) II, rat TFA，为CGRP受体激活剂，具有显著且持久的血管扩张效果，适用于心血管疾病研究。
T12293L	Olcegepant BIBN-4096,BIBN 4096BS	CGRP Receptor	GPCR/G Protein; Neuroscience
	Olcegepant (BIBN-4096) 是一种选择性的降钙素基因相关肽1 (CGRP1) 受体拮抗剂，IC50=0.03 nM，Ki=14.4 pM。
TP1040	Calcitonin (salmon) 鲑降钙素,Calcitonin salmon,Salmon calcitonin	CGRP Receptor	GPCR/G Protein; Neuroscience
	Calcitonin (salmon) 是一种阿米林和卡西宁受体的双激动剂，是一种钙调节激素，能够刺激骨的生成并能抑制骨吸收。
T4610	Rimegepant BMS 927711,BMS-927711,BMS927711,BHV-3000	CGRP Receptor	GPCR/G Protein; Neuroscience
	Rimegepant (BMS 927711) 是一种有效的降钙素基因相关肽 (CGRP) 受体拮抗剂，其 Ki=0.027 nM，IC50=0.14 nM。
T6590	MK-3207 Hydrochloride MK-3207 HCl	CGRP Receptor	GPCR/G Protein; Neuroscience
	MK-3207 Hydrochloride (MK-3207 HCl) 是口服具有活力的CGRP receptor 拮抗剂，IC50=0.12 nM，Ki=0.024 nM。
TP1134L	HCGRP-(8-37) acetate HCGRP-(8-37) acetate (119911-68-1 free base)	CGRP Receptor	GPCR/G Protein; Neuroscience
	HCGRP-(8-37) acetate 是一种人降钙素基因相关肽 (hCGRP) 片段醋酸盐，也是 CGRP 受体的拮抗剂。
T38734	Vazegepant Zavegepant,BHV-3500
	Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.
T76682	Galcanezumab LY 2951742	CGRP Receptor	GPCR/G Protein; Neuroscience
	Galcanezumab 是一种靶向 CGRP 配体的人源化 IgG4 单克隆抗体，是一种与配体降钙素基因相关肽结合的抗体。Galcanezumab 可用于预防和治疗偏头痛或丛集性头痛。
T76874	Erenumab AMG-334	CGRP Receptor	GPCR/G Protein; Neuroscience
	Erenumab是一种全人单克隆抗体，作用于抑制降钙素基因相关肽(CGRP)受体，用于预防发作性偏头痛。
TP1257L	Adrenomedullin (AM) (22-52), human acetate Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）	CGRP Receptor	GPCR/G Protein; Neuroscience
	Adrenomedullin (AM) (22-52), human acetate 是猫后肢血管床中 CGRP 受体和肾上腺髓质素受体的拮抗剂。
T16093	Telcagepant MK-0974	Others	Others
	Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively).
T12293	Olcegepant hydrochloride BIBN-4096 hydrochloride,BIBN4096BS hydrochloride	Others	Others
	Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP).
T76363	[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
	[Tyr22]CalcitoninGene Related Peptide, (22-37), rat 是一种大鼠降钙素基因相关肽 (CGRP) 的 22-37 片段，靶向CGRP 受体和腺苷酸环化酶。降钙素 (calcitonin) 主要由甲状腺 C 细胞产生，而 CGRP 则分泌并储存在神经系统中。
T39522	HTL22562
	HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.
T30537	BMS-694153 BMS694153,BMS 694153
	BMS-694153 is a potent and selective CGRP receptor antagonist.
T70820	MK-8825
	MK-8825 is a CGRP receptor antagonist.
T71246	DD04107
	DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.
T21558	MK-3207
	MK-3207是口服生物相容性的CGRP 受体拮抗剂，IC50和 Ki 分别为 0.12 nM 和 0.024 nM，对 AM1，AM2，CTR 和 AMY3 的抑制性较弱。MK-3207可用于偏头痛研究。
T26796	BI-44370
	BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.
T73703	(3R,5R,6S)-Atogepant
	(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) 是Atogepant 的异构体.Atogepant 是降钙素基因相关肽受体 (CGRP) 拮抗剂。Atogepant 可用于研究偏头痛。
TP2049	CRSP-1
	Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin recept
T76678	Eptinezumab
	Eptinezumab为人源化单克隆抗体，主要通过与降钙素基因相关肽(CGRP)结合，进而阻止其与受体相结合，用于成人偏头痛的预防。
TP1232	Amylin, amide, rat Amylin (rat)
	Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in ac
T75934	AC 187 TFA
	AC 187 TFA 是一种有效且具有口服活性的胰淀素受体 (amylin receptor) 拮抗剂，IC50为 0.48 nM，Ki 为 0.275 nM。AC 187 TFA 对胰淀素受体的选择性高于降钙素和 CGRP 受体。AC 187 TFA 具有神经保护作用。
T76680	Fremanezumab
	Fremanezumab (TEV-48125) 是一种人源化IgG2a 单克隆抗体，可选择性且有效地与降钙素基因相关肽 (CGRP) 结合。CGRP 是一种 37 个氨基酸的神经肽，参与偏头痛的中枢和外周病理生理事件。Fremanezumab 具有用于慢性偏头痛研究的潜力。
T70837	Rimegepant sulfate hydrate
	Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile.
T76473	Adrenotensin (human)
	Adrenotensin (human) (Pro-ADM-153-185 (human)) 是一种肾上腺髓质素前体肽的特定片段，具体为153至185位点。Adrenotensin (ADM)作为一个含有52个氨基酸的多功能肽，隶属于血管活性肽激素CGRP超家族。
T27025	Cizolirtine citrate E-4018,E4018,E 4018
	Cizolirtine is a calcitonin gene-related peptide antagonist. Cizolirtine may be useful for alleviating some neuropathic somatosensory disorders, in particular cold allodynia, with a reduced risk of undesirable side effects. Cizolirtine inhibits the spinal
TP2049L	CRSP-1 acetate(697327-12-1 Free base)
	CRSP-1 acetate(697327-12-1 Free base) 是一种内源性中枢降钙素(CT)受体激动剂，其刺激cAMP形成的效力是CT的350倍（ED50值分别为0.2和71nM）。CRSP-1 acetate 对降钙素基因相关肽 (CGRP) 和肾上腺髓质素受体没有活性。CRSP-1 acetate 抑制多核破骨细胞的形成，其体外功效与CT相似。CRSP-1 acetate 抑制自由进食大鼠的食物摄入并升高体温，并显着降低体内血浆钙水平。

化合物

CGRP 8-37 (rat)

Cat.No: TP1323

Target: CGRP Receptor

CGRP (rat) acetate

Cat.No: TP2233L

Target: Others

CGRP antagonist 1

Cat.No: T13453

Target: CGRP Receptor

α-CGRP (human) acetate

Cat.No: TP2044L

Synonym: 人类降钙素基因相关肽 1,α-CGRP (human) acetate (90954-53-3 free base)

Target: Others

CGRP (83-119), rat TFA

Cat.No: TP1200

Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA

Target: Others

β-CGRP, human

Cat.No: TP1130

Synonym: CGRP-II (Human),Human β-CGRP

Cat.No: TP2233

Synonym: CGRP (rat)

Target: Others

α-CGRP(human)

Cat.No: TP2044

Synonym: α-CGRP (human)

Calcitonin Gene Related Peptide (CGRP) II, rat

Cat.No: TP1202

Synonym: CGRP II, rat

CGRP(83-119), rat

Cat.No: TP1203

Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat

β-CGRP, human TFA (101462-82-2 free base)

Cat.No: TP1131

Synonym: CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA

CGRP II, rat (TFA) (99889-63-1 free base)

Cat.No: TP1201

Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)

Tyr-α-CGRP (rat) (trifluoroacetate salt)

Cat.No: T38190

Tyr-α-CGRP (human) (trifluoroacetate salt)

Cat.No: T36555

Cat.No: TP1134

Synonym: Human α-CGRP (8-37)

β-CGRP, human TFA

Cat.No: T75978

α-CGRP, rat TFA

Cat.No: T75732

α-CGRP(human) TFA

Cat.No: T75788

α-CGRP (mouse, rat) TFA

Cat.No: T78540

Target: CGRP Receptor

Vazegepant hydrochloride

Cat.No: T8682

Synonym: Vazegepant HCl

Target: CGRP Receptor

Cat.No: T17194

Synonym: MK-1602

Target: CGRP Receptor

Calcitonin Gene Related Peptide (CGRP) II, rat TFA

Cat.No: T76032

Cat.No: T12293L

Synonym: BIBN-4096,BIBN 4096BS

Target: CGRP Receptor

Calcitonin (salmon)

Cat.No: TP1040

Synonym: 鲑降钙素,Calcitonin salmon,Salmon calcitonin

Target: CGRP Receptor

Cat.No: T4610

Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000

Target: CGRP Receptor

MK-3207 Hydrochloride

Cat.No: T6590

Synonym: MK-3207 HCl

Target: CGRP Receptor

HCGRP-(8-37) acetate

Cat.No: TP1134L

Synonym: HCGRP-(8-37) acetate (119911-68-1 free base)

Target: CGRP Receptor

Cat.No: T38734

Synonym: Zavegepant,BHV-3500

Cat.No: T76682

Synonym: LY 2951742

Target: CGRP Receptor

Cat.No: T76874

Synonym: AMG-334

Target: CGRP Receptor

Adrenomedullin (AM) (22-52), human acetate

Cat.No: TP1257L

Synonym: Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）

Target: CGRP Receptor

Cat.No: T16093

Synonym: MK-0974

Target: Others

Olcegepant hydrochloride

Cat.No: T12293

Synonym: BIBN-4096 hydrochloride,BIBN4096BS hydrochloride

Target: Others

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat

Cat.No: T76363

Cat.No: T39522

Cat.No: T30537

Synonym: BMS694153,BMS 694153

Cat.No: T70820

Cat.No: T71246

Cat.No: T21558

Cat.No: T26796

(3R,5R,6S)-Atogepant

Cat.No: T73703

Cat.No: TP2049

Cat.No: T76678

Amylin, amide, rat

Cat.No: TP1232

Synonym: Amylin (rat)

Cat.No: T75934

Cat.No: T76680

Rimegepant sulfate hydrate

Cat.No: T70837

Adrenotensin (human)

Cat.No: T76473

Cizolirtine citrate

Cat.No: T27025

Synonym: E-4018,E4018,E 4018

CRSP-1 acetate(697327-12-1 Free base)

Cat.No: TP2049L

Cat. No.	Product Name	Target	Signaling Pathways
TP2167	β-CGRP, human acetate β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate	CGRP Receptor	GPCR/G Protein; Neuroscience
	β-CGRP, human acetate 是降钙素肽之一，通过受体活性修饰蛋白 (RAMP) 和降钙素受体样受体 (CRLR) 的复合物发挥作用（对于 CRLR/RAMP1 和 CRLR，IC50：1 nM 和 300 nM /RAMP2 在单元格中）。
T21581L	AC 187 Acetate AC 187 Acetate (151804-77-2 Free base)	Amylin Receptor	GPCR/G Protein
	AC 187 Acetate 是胰淀素受体的强效拮抗剂。AC 187 对胰淀素受体的选择性高于降钙素和 CGRP 受体。

天然产物

β-CGRP, human acetate

Cat.No: TP2167

Synonym: β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate

Target: CGRP Receptor

Cat.No: T21581L

Synonym: AC 187 Acetate (151804-77-2 Free base)

Target: Amylin Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00678	CALCA/CGRP Protein, Mouse, Recombinant (hFc) CGRP,Katacalcin,PDN-21,CGRP-I,CGRP	Mouse	HEK293 Cells
	Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 assay, and osteogenic differentiation with osteogenic staining, qPCR, and repair of calvarial defect. Furthermore, 5-azacytidine (5-az) was used to intervene ASCs-T2DM to verify the relationship between the methylation level of the target fragment and expression of Calca.
TMPY-04120	Procalcitonin/CALCA Protein, Human, Recombinant (mFc) Procalcitonin,CGRP,CGRP-I,calcitonin-relat...	Human	HEK293 Cells
	Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1.
TMPY-00066	Procalcitonin/CALCA Protein, Human, Recombinant (His) KC,CGRP,CALC1,Procalcitonin,CT,calcitonin-related p...	Human	HEK293 Cells
	Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1.
TMPH-01025	CALCA Protein, Human, Recombinant (GST) Calcitonin gene-related peptide 1,CGRP-I,CALCA,CALC...	Human	E. coli
	CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CALCA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 30.6 kDa and the accession number is P06881.
TMPY-03963	CALCB Protein, Human, Recombinant (mFc) CGRP-II,calcitonin-related polypeptide β,calcitonin...	Human	HEK293 Cells
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of ...
TMPY-01466	S100A12 Protein, Human, Recombinant MRP6,MRP-6,S100A12,S100 calcium binding protein A12,CAGC,p6,...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-00371	STC1 Protein, Human, Recombinant (His) stanniocalcin 1,STC	Human	HEK293 Cells
	Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has myriad functions, including the maintenance of calcium homeostasis, the promotion of early wound healing, uncoupling respiration (aerobic glycolysis), reepithelialization in damaged tissues, the inhibition of vascular leakage, and the regulation of macrophage functions to keep e...
TMPY-03280	RAMP3 Protein, Human, Recombinant (hFc) receptor (G protein-coupled) activity modifying protein 3	Human	HEK293 Cells
	RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transp...
TMPJ-00362	MMP-2 Protein, Human, Recombinant (His) 72 kDa Gelatinase,TBE-1,Gelatinase A,Matrix Metalloproteinas...	Human	HEK293 Cells
	72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathologic...
TMPY-02839	Adrenomedullin Protein, Human, Recombinant (hFc) AM,PAMP,adrenomedullin	Human	HEK293 Cells
	Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the calcitonin gene-related peptide. Adrenomedullin has a highly expression in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been report...
TMPH-01282	ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) PNEM,ELAVL4,HuD,Hu-antigen D,ELAV-like protein 4	Human	E. coli
	RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (UTR) of target mRNAs, including GAP43, VEGF, FOS, CDKN1A and ACHE mRNA. Many of the target mRNAs are coding for RNA-binding proteins, transcription factors and proteins involved in RNA processing and/or neuronal development and function. By binding to th...

重组蛋白

CALCA/CGRP Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00678

Species: Mouse

Expression System: HEK293 Cells

Procalcitonin/CALCA Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04120

Species: Human

Expression System: HEK293 Cells

Procalcitonin/CALCA Protein, Human, Recombinant (His)

Cat.No: TMPY-00066

Species: Human

Expression System: HEK293 Cells

CALCA Protein, Human, Recombinant (GST)

Cat.No: TMPH-01025

Species: Human

Expression System: E. coli

CALCB Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03963

Species: Human

Expression System: HEK293 Cells

S100A12 Protein, Human, Recombinant

Cat.No: TMPY-01466

Species: Human

Expression System: E. coli

STC1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00371

Species: Human

Expression System: HEK293 Cells

RAMP3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03280

Species: Human

Expression System: HEK293 Cells

MMP-2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00362

Species: Human

Expression System: HEK293 Cells

Adrenomedullin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02839

Species: Human

Expression System: HEK293 Cells

ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01282

Species: Human

Expression System: E. coli

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