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细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
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搜索结果

Search Results for " cd25 "
Targets Recommended: TGF-beta/Smad

8

抑制剂 & 化合物

28

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8730 BMS986260

TGF-beta/Smad Stem Cells
BMS986260是一种口服有活力的选择性TGFβR1抑制剂，是免疫肿瘤学药物。它能够抑制 MINK 和 NHLF 细胞系中 TGFβ 介导的 pSMAD2/3 核转位，IC50值分别为 350 nM 和 190 nM。它对 TGFβR1 的选择比 TGFβR2 同功酶高。
T14569 BI8626

E1/E2/E3 Enzyme Ubiquitination
BI8626 是一种泛素连接酶 HUWE1 抑制剂，对 NOD/ShiLtj 小鼠自发性干燥综合征具有保护作用。BI8626 抑制细胞内胆固醇并降低磷酸化 ZAP-70、CD25 和其他激活标志物的表达，抑制 CD4 T 细胞的增殖。
T73689 Daclizumab

Ro 24-7375,Zenapax

 IL Receptor Immunology/Inflammation
Daclizumab （Zenapax）为人源化单抗，能特异性地抑制IL-2R-HA的α亚单位。Daclizumab （Zenapax）能通过与CD25的特异性结合而抑制IL-2和IL-2R-HA的结合。Daclizumab （Zenapax）研究多发性硬化症 。
T76770 Camidanlumab

Camidanlumab (HuMax-TAC) 作为一种CD25单克隆抗体，专门针对细胞表面CD25抗原，该抗原在多种血液肿瘤中过度表达，而在正常组织的表达则有限。因其特定目标，Camidanlumab被广泛应用于合成抗体活性分子偶联物(ADCs)，旨在针对包括淋巴瘤和白血病在内的多种疾病进行研究。
T80854 Vopikitug

Vopikitug为IgG1-kappa型人源单克隆抗体，针对IL-2RA（白细胞介素2受体α亚基，亦称IL-2RA、TAC、p55、CD25）具有特异性，并展现出抗肿瘤活性。
T81308 RDN2150

RDN2150（Compound 25）为一种ZAP-70抑制剂，IC50值为14.6 nM。该化合物通过与ZAP-70的C346残基共价结合，有效抑制CD25和CD69的表达，进而阻断CD4+T细胞的活化。RDN2150可作为银屑病研究中的潜在工具。
T73697 Denileukin diftitox

Denileukin diftitox (DAB 389IL-2) 是一种融合蛋白毒素，将白喉毒素 (DT) 与白细胞介素 2 (IL-2) 结合，专门针对表达高亲和力IL-2受体 (IL-2R)、CD25 的细胞。它通过与IL-2R阳性细胞结合并利用白喉毒素片段的内化作用来抑制蛋白质合成，从而达到耗尽目标细胞的效果。
T25050 Alloferon 3

Alloferon 3 is a natural peptide that mediates signaling by the NF-kappa B pathway to enhance the recognition of viral and tumor antigens. It is known to induce the production of endogenic interferons that promote a cascade of defense responses and also e

化合物

BMS986260
Cat.No: T8730
Synonym:
Target: TGF-beta/Smad
BI8626
Cat.No: T14569
Synonym:
Target: E1/E2/E3 Enzyme
Daclizumab
Cat.No: T73689
Synonym: Ro 24-7375,Zenapax
Target: IL Receptor
Camidanlumab
Cat.No: T76770
Synonym:
Target:
Vopikitug
Cat.No: T80854
Synonym:
Target:
RDN2150
Cat.No: T81308
Synonym:
Target:
Denileukin diftitox
Cat.No: T73697
Synonym:
Target:
Alloferon 3
Cat.No: T25050
Synonym:
Target:
Species：
Human (16)
Mouse (6)
Cynomolgus (4)
Rat (1)
Rhesus (1)
Expression System：
HEK293 Cells (24)
E. coli (2)
Baculovirus Insect Cells (1)
P. pastoris (Yeast) (1)
Tag：
C-His (5)
Tag Free (4)
C-hFc (3)
N-hFc (3)
C-His-Avi (2)
His, Avi (2)
N-6xHis (2)
N-rFc (2)
N-6xHis-Avi (1)
N-6xHis-Flag (1)
Cat. No. Product Name Species Expression System
TMPY-01923 CD25/IL2R alpha Protein, Mouse, Recombinant (His)

Il2r,CD25,interleukin 2 receptor, alpha,in...

 Mouse HEK293 Cells
CD25/IL2R alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P01590.
TMPY-05584 CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

CD25,p55,interleukin 2 receptor, alpha,TCG...

 Human HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25 kDa and the accession number is P01589.
TMPY-01103 CD25/IL2R alpha Protein, Human, Recombinant (His)

interleukin 2 receptor, α,IL-2RA,IDDM10,IL2R,interleukin 2 r...

 Human HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01589.
TMPY-05644 CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated

interleukin 2 receptor, α,CD25/IL2R α,inte...

 Rhesus HEK293 Cells
CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24.9 kDa and the accession number is Q5MNY4.
TMPY-05090 CD25/IL2R alpha Protein, Rat, Recombinant (His)

interleukin 2 receptor, α,CD25/IL2R α,inte...

 Rat Baculovirus Insect Cells
CD25/IL2R alpha Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is A6JLS0.
TMPY-03776 CD25/IL2R alpha Protein, Cynomolgus, Recombinant

interleukin 2 receptor, α,interleukin 2 receptor, alpha,...

 Cynomolgus HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.4 kDa and the accession number is H6WS54.
TMPY-03644 CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)

interleukin 2 receptor, alpha,CD25/IL2R α,...

 Cynomolgus HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is H6WS54.
TMPK-00165 IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated

IL2RA,CD25,IL-2 R alpha,TCGFR,IL-2 R α/

Human HEK293 Cells
Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C...
TMPY-05541 CD25/IL2R alpha Protein, Mouse, Recombinant (hFc)

Ly-43,Il2r,interleukin 2 receptor, α,CD25,...

 Mouse HEK293 Cells
CD25/IL2R alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.4 kDa and the accession number is P01590.
TMPY-00858 CD25/IL2R alpha Protein, Human, Recombinant (hFc)

CD25,interleukin 2 receptor, alpha,IL2R,ID...

 Human HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is P01589.
TMPK-00164 IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)

IL-2 R alpha,IL-2 R α,IL2RA,IL2R,TCGFR,IDDM10,CD

Human HEK293 Cells
Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. ...
TMPY-03740 CD25/IL2R alpha Protein, Cynomolgus, Recombinant (hFc)

interleukin 2 receptor, α,interleukin 2 receptor, alpha,...

 Cynomolgus HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.7 kDa and the accession number is H6WS54.
TMPY-03674 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)

sOdf,tumor necrosis factor (ligand) superfamily, member 11,T...

 Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 52.4 kDa and the accession number is AAC51762.1.
TMPY-02726 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)

RANKL,OPGL,Trance,OPG,tumor necrosis factor (ligand) superfa...

 Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is AAC40113.1.
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

Receptor activator of nuclear factor κ-B ligand,Osteoprotege...

 Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Receptor activator of nuclear factor kappa-B ligand,Receptor...

 Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPY-03364 RANKL/TNFSF11/CD254 Protein, Human, Recombinant

sOdf,OPTB2,TNFSF11,TRANCE,hRANKL2,ODF,OPGL,RANKL,tumor necro...

 Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is AAC51762.1.
TMPY-03527 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)

CD254,tumor necrosis factor (ligand) super...

 Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa and the accession number is O14788-2.
TMPJ-01472 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)

Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 23-29 KDa and the accession number is O35235-1.
TMPK-00716 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)

OPGL,TRANCE,OPTB2,TNFSF11,ODF,sOdf,RANKL,CD25

Human HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant ...
TMPY-01471 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)

TRANCE,sOdf,CD254,hRANKL2,TNFSF11,ODF,OPTB...

 Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is AAC51762.1.
TMPY-00537 RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)

tumor necrosis factor (ligand) superfamily, member 11

 Cynomolgus HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is G7PW41.
TMPK-00717 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)

OPGL,CD254,TRANCE,ODF,RANKL,TNFSF11,OPTB2,...

 Human HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Human, Recombinant ...
TMPY-06561 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (rFc)

OPTB2,OPGL,hRANKL2,CD254,sOdf,tumor necros...

 Human HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 46.18 kDa and the accession number is AAC51762.1.
TMPK-00591 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)

CD254,OPGL,TNFSF11,TRANCE,ODF,sOdf,OPTB2,R...

 Mouse HEK293 Cells
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant ...
TMPH-01872 Plastin-2 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 86.2 kDa and the accession number is P13796.
TMPH-01871 Plastin-2 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 72.2 kDa and the accession number is P13796.
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated

transforming growth factor β1,TGFβ,CED,TGFB,TGFbeta,LAP (TGF...

 Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ...

重组蛋白

CD25/IL2R alpha Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01923
Species: Mouse
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05584
Species: Human
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-01103
Species: Human
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05644
Species: Rhesus
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Rat, Recombinant (His)
Cat.No: TMPY-05090
Species: Rat
Expression System: Baculovirus Insect Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant
Cat.No: TMPY-03776
Species: Cynomolgus
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03644
Species: Cynomolgus
Expression System: HEK293 Cells
IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00165
Species: Human
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05541
Species: Mouse
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00858
Species: Human
Expression System: HEK293 Cells
IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00164
Species: Human
Expression System: HEK293 Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03740
Species: Cynomolgus
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03674
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02726
Species: Mouse
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00607
Species: Mouse
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Cat.No: TMPJ-00662
Species: Human
Expression System: E. coli
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
Cat.No: TMPY-03364
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
Cat.No: TMPY-03527
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His)
Cat.No: TMPJ-01472
Species: Mouse
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
Cat.No: TMPK-00716
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01471
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-00537
Species: Cynomolgus
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00717
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (rFc)
Cat.No: TMPY-06561
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
Cat.No: TMPK-00591
Species: Mouse
Expression System: HEK293 Cells
Plastin-2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01872
Species: Human
Expression System: E. coli
Plastin-2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01871
Species: Human
Expression System: P. pastoris (Yeast)
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00250
Species: Human
Expression System: HEK293 Cells
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