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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T74492 |
CD22 ligand-1
|
||
CD22ligand-1 (compound 12) 是一种有效的选择性CD22配体,对 hCD22 和 MAG 的KD 值分别为 0.335、30.7 µM。CD22ligand-1 具有研究 B 细胞相关疾病的潜力。 | |||
T76790 |
Inotuzumab
|
Others | Others |
Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) 是人源化靶向 CD22 的 IgG4 抗体。Inotuzumab 是 Inotuzumab ozogamicin 的裸抗,可用于合成抗体-活性分子偶联物 (Inotuzumab ozogamicin)。Inotuzumab 可于研究急性淋巴细胞白血病和非霍奇金淋巴瘤。 | |||
T18321 |
Mc-Val-Cit-PAB-Cl
|
Others | Others |
Mc-Val-Cit-PAB-Cl 是一种可切割的 ADC 接头,可用于偶联 MMAE 和抗体以形成抗体-MC-vc-MMAE。 | |||
T38493 |
MCC-DM1
MCC-DM1 |
||
MCC-DM1 is a drug-Linker Conjugates for ADC such ad Anti-CD22-MCC-DM1. | |||
T76693 | Moxetumomab | ||
Moxetumomab 是一种靶向重组CD22的免疫毒素。可用于研究毛细胞白血病 (HCL)。 | |||
T76768 | Pinatuzumab | ||
Pinatuzumab为针对CD22细胞表面抗原的单克隆抗体。作为合成抗体活性分子偶联物(ADC)成分,适用于非霍奇金淋巴瘤(NHL)等多种疾病的研究。 | |||
T76783 | Moxetumomab pasudotox | ||
Moxetumomab pasudotox (CAT 8015) 是一种抗CD22免疫毒素,含有抗CD22Fv 和Pseudomonas exotoxin。CD22是在多种恶性 B 细胞上表达的细胞表面受体。Moxetumomab pasudotox 可用于毛细胞白血病 (HCL) 的研究。 | |||
T76805 | Epratuzumab | ||
Epratuzumab(Antibody hLL 2)是一种针对CD22的IgG1型单克隆抗体,功能包括肿瘤成像和免疫调节。它能够诱发CD22磷酸化,主要应用于非霍奇金淋巴瘤和若干自身免疫性疾病的研究中。 | |||
T76920 | Bectumomab | ||
Bectumomab (IMMU-LL 2) 是一种针对人CD22(抗原) 的人源化IgG2a 单抗。Bectumomab 也是一种抗淋巴瘤抗体片段。Bectumomab 可与锝 99 (Tc99m LL2 Fab) 联合用于成像。此外,Bectumomab 能够检查复发性或新诊断的非霍奇金淋巴瘤 (NHL) 的分期,并在放射免疫研究 (RIT) 前评估靶向性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05201 |
Siglec-2/CD22 Protein, Human, Recombinant
CD22 molecule,SIGLEC2,SIGLEC-2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1. | |||
TMPY-04083 |
Siglec-2/CD22 Protein, Mouse, Recombinant (His)
A530093D23,Lyb8,CD22 molecule,Lyb-8 |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.8 kDa and the accession number is Q3U0M3. | |||
TMPY-05566 |
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
CD22 molecule,SIGLEC-2,SIGLEC2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1. | |||
TMPY-02034 |
Siglec-2/CD22 Protein, Human, Recombinant (His)
CD22 molecule,SIGLEC2,SIGLEC-2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPY-03360 |
Siglec-2/CD22 Protein, Rhesus, Recombinant (hFc)
CD22 molecule |
Rhesus | HEK293 Cells |
Siglec-2/CD22 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102.1 kDa and the accession number is EHH29920.1. | |||
TMPY-00158 |
Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
CD22 molecule |
Rat | HEK293 Cells |
Siglec-2/CD22 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102 kDa and the accession number is A6JA30. | |||
TMPY-00349 |
Siglec-2/CD22 Protein, Rhesus, Recombinant (His)
CD22 molecule |
Rhesus | HEK293 Cells |
Siglec-2/CD22 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.5 kDa and the accession number is EHH29920.1. | |||
TMPY-00407 |
Siglec-2/CD22 Protein, Rat, Recombinant (His)
CD22 molecule |
Rat | HEK293 Cells |
Siglec-2/CD22 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.7 kDa and the accession number is A6JA30. | |||
TMPY-03895 |
Siglec-2/CD22 Protein, Mouse, Recombinant (hFc)
Lyb-8,Lyb8,A530093D23,CD22 molecule |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 104.3 kDa and the accession number is Q3U0M3. | |||
TMPJ-00444 |
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)
CD22 antigenMGC130020,B-cell receptor ... |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1. | |||
TMPY-05223 |
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
SIGLEC-2,CD22 molecule,SIGLEC2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPJ-00393 |
Siglec-2/CD22 Protein, Human, Recombinant (hFc)
BL-CAM,SIGLEC2FLJ22814,CD22 antig... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is P20273. | |||
TMPY-05598 |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
SIGLEC2,SIGLEC-2,CD22 molecule |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4. | |||
TMPJ-00392 |
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
T-cell surface antigen Leu-14,CD22 molecul... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 110-130 KDa and the accession number is P20273. | |||
TMPY-03566 |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His)
CD22 molecule,SIGLEC2,SIGLEC-2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q32M46. | |||
TMPY-05316 |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
CD22 molecule,SIGLEC-2,SIGLEC2 |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q32M46. | |||
TMPY-01152 |
DNAM-1/CD226 Protein, Human, Recombinant (His)
CD226 molecule,DNAM-1,TLiSA1,PTA1,DNAM1 |
Human | HEK293 Cells |
CD226 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is Q15762. | |||
TMPY-00834 |
IGF1R/CD221 Protein, Human, Recombinant (His)
IGF-I R,IGFR,IGFIR,IGF1 Receptor,JTK13,insulin-like growth f... |
Human | HEK293 Cells |
IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069. | |||
TMPY-06192 |
CD226 Protein, Cynomolgus, Recombinant (His)
CD226 molecule |
Cynomolgus | HEK293 Cells |
CD226 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is A0A2K5W1Z6-1. | |||
TMPY-05487 |
DNAM-1/CD226 Protein, Human, Recombinant (hFc)
PTA1,DNAM1,TLiSA1,DNAM-1,CD226 molecule |
Human | HEK293 Cells |
CD226 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.7 kDa and the accession number is Q15762. | |||
TMPK-00456 |
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
CD221,MGC142172,IGFIR,IGFR,MGC18216,JTK13,... |
Human | HEK293 Cells |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated is expressed in ... | |||
TMPK-00229 |
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)
PTA1,TLiSA1,DNAM1,CD226,CD22<... |
Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.9 kDa... | |||
TMPK-00358 |
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
T100,Lgp100,LY9,AI893573,CD229,SLAMF3 |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi), B... | |||
TMPY-03348 |
CD226 Protein, Rat, Recombinant (hFc)
CD226 molecule |
Rat | HEK293 Cells |
CD226 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.6 kDa and the accession number is D3ZS97. | |||
TMPY-06905 |
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
CD221,insulin-like growth factor 1 recepto... |
Human | HEK293 Cells |
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1. | |||
TMPY-05226 |
DNAM-1/CD226 Protein, Human, Recombinant (His), Biotinylated
CD226 molecule,DNAM1,PTA1,TLiSA1,DNAM-1 |
Human | HEK293 Cells |
CD226 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is Q15762. | |||
TMPK-00789 |
CD228 Protein, Human, Recombinant (His)
MFI2,MAP97,MELTF,Melanotransferrin,CD228 |
Human | HEK293 Cells |
Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition. | |||
TMPY-00070 |
CD226 Protein, Rat, Recombinant (His)
CD226 molecule |
Rat | HEK293 Cells |
CD226 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is A6K5P0. | |||
TMPY-04360 |
IGF1R/CD221 Protein, Human, Recombinant (His & GST)
JTK13,insulin-like growth factor 1 receptor,IGF1 Receptor, |
Human | Baculovirus Insect Cells |
IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069. | |||
TMPK-00455 |
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
MGC142172,IGF-I receptor,IGF-I R,IGF-1R,MGC18216,MGC142170,I... |
Human | HEK293 Cells |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells wi... | |||
TMPY-06195 |
IGF1R/CD221 Protein, Mouse, Recombinant (His)
insulin-like growth factor 1 receptor,CD22... |
Mouse | HEK293 Cells |
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105.2 kDa and the accession number is E9QNX9. | |||
TMPK-00658 |
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
CD221,IGFR,IGF1R,MGC142172,MGC18216,IGF-1R... |
Cynomolgus | HEK293 Cells |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target. IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells wit... | |||
TMPY-01177 |
DNAM-1/CD226 Protein, Mouse, Recombinant (His)
CD226 molecule,DNAM1,TLiSA1,Pta1,BC051526,... |
Mouse | HEK293 Cells |
CD226 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q5DW69. | |||
TMPK-00357 |
CD229 Protein, Human, Recombinant (His & Avi)
LY9,T100,AI893573,SLAMF3,Lgp100,CD229 |
Human | HEK293 Cells |
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells. CD229 Protein, Human, Recombinant (His & Avi) is... | |||
TMPK-00230 |
DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated
CD226,PTA1,CD226 molecul... |
Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weig... | |||
TMPY-01804 |
CD229 Protein, Mouse, Recombinant (His)
T100,SLAMF3,CD229,AI893573,Lgp100,lymphocy... |
Mouse | HEK293 Cells |
CD229 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is Q01965. |