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Search Results for " cd147 "

Targets Recommended: Autophagy

5

抑制剂 & 化合物

10

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14091	AC-73	Autophagy	Autophagy
	AC-73 是一种可口服的 Cluster of Differentiation 147 (CD147) 抑制剂，具有很高的生物利用，可选择性破坏 CD147 的二聚化 (结合位点在 CD147 的 N 端 IgC2 域中包括 Glu64 和 Glu73)，从而对 CD147/ERK1/2/STAT3/MMP-2 途径产生抑制，并抑制肝癌细胞的运动和侵袭。AC-73 具有抗增殖活性，诱导白血病细胞自噬。
T12981	SP-8356	Autophagy	Autophagy
	SP-8356 是一种有效的、口服活性的分化簇 147 (CD147) 抑制剂，具有抗动脉粥样硬化作用。
T9931	meplazumab	Others	Others
	meplazumab 是一种人源化抗 CD147 抗体，作为 COVID-19 肺炎患者的附加疗法。
T82331	Gavilimomab ABX-CBL
	Gavilimomab (ABX-CBL)为IgM亚型小鼠单克隆抗体，针对细胞表面的CD147进行特异性识别，并通过激活补体系统引发的细胞裂解实现细胞杀伤作用。该抗体主要用于移植物抗宿主病（GVHD）研究领域。
T80726	Ziralimumab ABX-RB2
	Ziralimumab (ABX-RB2)为针对人类CD147/BSG的单克隆抗体，其应用于免疫抑制。

化合物

Cat.No: T14091

Target: Autophagy

Cat.No: T12981

Target: Autophagy

Cat.No: T9931

Target: Others

Cat.No: T82331

Synonym: ABX-CBL

Cat.No: T80726

Synonym: ABX-RB2

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01334	EMMPRIN/CD147 Protein, Canine, Recombinant (His) Basigin,BSG,M6,OK,5F7,TCSF,CD147	Canine	HEK293 Cells
	CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
TMPY-00685	EMMPRIN/CD147 Protein, Human, Recombinant CD147,TCSF,5F7,Basigin,OK,M6,basigin (Ok b...	Human	HEK293 Cells
	EMMPRIN/CD147 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.7 kDa and the accession number is P35613-2.
TMPY-00684	EMMPRIN/CD147 Protein, Human, Recombinant (hFc) EMMPRIN,CD147,OK,M6,TCSF,Basigin,5F7,basig...	Human	HEK293 Cells
	EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is P35613-2.
TMPJ-00159	EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated Membrane glycoprotein gp42,Basigin,HT7 antigen,Bsg,Basic imm...	Human	HEK293 Cells
	Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore...
TMPY-01316	EMMPRIN/CD147 Protein, Mouse, Recombinant (His) CD147,HT-7,AI115436,AI325119,EMMPRIN,basig...	Mouse	HEK293 Cells
	EMMPRIN/CD147 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P18572-2.
TMPY-01315	EMMPRIN/CD147 Protein, Mouse, Recombinant (His & hFc) AI325119,CD147,basigin (Ok blood group),HT...	Mouse	HEK293 Cells
	EMMPRIN/CD147 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 48.6 kDa and the accession number is P18572-2.
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His) 5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived Collagena...	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,...
TMPH-00998	CD147 Protein, Human, Recombinant (aa 138-323, hFc) HAb18G,BSG,Basigin,CD147,EMMPRIN,Extracell...	Human	HEK293 Cells
	CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.
TMPY-06019	EMMPRIN/CD147 Protein, Cynomolgus, Recombinant (His) basigin (Ok blood group)	Cynomolgus	HEK293 Cells
	EMMPRIN/CD147 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.4 kDa and the accession number is XP_005587354.1.
TMPJ-00352	CD98 Protein, Human, Recombinant (mFc) Lymphocyte activation antigen 4F2 large subunit,4F2 cell-sur...	Human	HEK293 Cells
	CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin 1 function to promote cyclosporine B-induced cell adhesion and p44/p42 MAPK activation following PI3K activation. CD98 heavy chain has been studied to be a key player in tumorigenesis due to its role in activating integrin signaling to promote tumor progression via angiogenesis,...

重组蛋白

EMMPRIN/CD147 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01334

Species: Canine

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant

Cat.No: TMPY-00685

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00684

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00159

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01316

Species: Mouse

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01315

Species: Mouse

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00160

Species: Human

Expression System: HEK293 Cells

CD147 Protein, Human, Recombinant (aa 138-323, hFc)

Cat.No: TMPH-00998

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06019

Species: Cynomolgus

Expression System: HEK293 Cells

CD98 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00352

Species: Human

Expression System: HEK293 Cells

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